6EXJ

PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2

Summary for 6EXJ

Entry DOI	10.2210/pdb6exj/pdb
Related	5OVA 5OVC 5OVP 5OVV
Descriptor	SH3 and multiple ankyrin repeat domains protein 3, SSTR2 (3 entities in total)
Functional Keywords	pdz domain, peptide binding, post-synaptic density, c terminus, protein binding
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	4
Total formula weight	22203.54
Authors	Ponna, S.K.,Keller, C.,Ruskamo, S.,Myllykoski, M.,Boeckers, T.M.,Kursula, P. (deposition date: 2017-11-08, release date: 2018-03-07, Last modification date: 2024-01-17)
Primary citation	Ponna, S.K.,Ruskamo, S.,Myllykoski, M.,Keller, C.,Boeckers, T.M.,Kursula, P. Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3. J. Neurochem., 145:449-463, 2018 Cited by PubMed: 29473168 DOI: 10.1111/jnc.14322 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation