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1PEG
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BU of 1peg by Molmil
Structural basis for the product specificity of histone lysine methyltransferases
Descriptor: Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
Authors:Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X.
Deposit date:2003-05-21
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
1F3L
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BU of 1f3l by Molmil
CRYSTAL STRUCTURE OF THE CONSERVED CORE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT3
Descriptor: PROTEIN ARGININE METHYLTRANSFERASE PRMT3, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Zhang, X, Zhou, L, Cheng, X.
Deposit date:2000-06-05
Release date:2001-03-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of the conserved core of protein arginine methyltransferase PRMT3.
EMBO J., 19, 2000
1NCN
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BU of 1ncn by Molmil
the receptor-binding domain of human B7-2
Descriptor: T lymphocyte activation antigen CD86
Authors:Zhang, X, Schwartz, J.D, Almo, S.C, Nathenson, S.G.
Deposit date:2002-12-05
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Receptor-Binding Domain of Human B7-2: Insights into Organization and Signaling
Proc.Natl.Acad.Sci.USA, 100, 2003
7W5B
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BU of 7w5b by Molmil
The cryo-EM structure of human C* complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2021-11-29
Release date:2022-06-22
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W5A
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BU of 7w5a by Molmil
The cryo-EM structure of human pre-C*-II complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2021-11-29
Release date:2022-06-22
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W59
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BU of 7w59 by Molmil
The cryo-EM structure of human pre-C*-I complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Zhan, X, Lu, Y, Shi, Y.
Deposit date:2021-11-29
Release date:2022-06-22
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
5XBM
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BU of 5xbm by Molmil
Structure of SCARB2-JL2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ...
Authors:Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L.
Deposit date:2017-03-20
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
1AI0
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BU of 1ai0 by Molmil
R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES
Descriptor: PHENOL, R6 INSULIN HEXAMER, ZINC ION
Authors:Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J.
Deposit date:1997-04-30
Release date:1997-11-12
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
1H0C
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BU of 1h0c by Molmil
The crystal structure of human alanine:glyoxylate aminotransferase
Descriptor: (AMINOOXY)ACETIC ACID, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Zhang, X, Danpure, C.J, Roe, S.M, Pearl, L.H.
Deposit date:2002-06-17
Release date:2003-06-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Alanine:Glyoxylate Aminotransferase and the Relationship between Genotype and Enzymatic Phenotype in Primary Hyperoxaluria Type 1.
J.Mol.Biol., 331, 2003
1AIY
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BU of 1aiy by Molmil
R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES
Descriptor: PHENOL, R6 INSULIN HEXAMER, ZINC ION
Authors:Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J.
Deposit date:1997-04-30
Release date:1997-11-12
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
8HMY
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BU of 8hmy by Molmil
Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex
Descriptor: Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ...
Authors:Zhang, X, Yang, F, Zhan, X, Shi, Y.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
8HMZ
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BU of 8hmz by Molmil
Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex
Descriptor: Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ...
Authors:Zhang, X, Yang, F, Zhan, X, Shi, Y.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
6IMB
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BU of 6imb by Molmil
Crystal structure of PDE4D complexed with a novel inhibitor
Descriptor: 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ...
Authors:Zhang, X, Su, H, Xu, Y.
Deposit date:2018-10-22
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMI
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BU of 6imi by Molmil
Crystal structure of PDE4D complexed with a novel inhibitor
Descriptor: 1,2-ETHANEDIOL, 6-ethoxy-7-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ...
Authors:Zhang, X, Su, H, Xu, Y.
Deposit date:2018-10-23
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMD
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BU of 6imd by Molmil
Crystal structure of PDE4D complexed with a novel inhibitor
Descriptor: 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ...
Authors:Zhang, X, Su, H, Xu, Y.
Deposit date:2018-10-22
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
5GTX
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BU of 5gtx by Molmil
Crystal structure of mutated buckwheat glutaredoxin
Descriptor: buckwheat glutaredoxin
Authors:Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H.
Deposit date:2016-08-23
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity
J. Inorg. Biochem., 173, 2017
5KQA
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BU of 5kqa by Molmil
Crystal structure of buckwheat glutaredoxin-glutathione complex
Descriptor: GLUTATHIONE, Glutaredoxin-glutathione complex
Authors:Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H.
Deposit date:2016-07-06
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity
J. Inorg. Biochem., 173, 2017
5Z58
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BU of 5z58 by Molmil
Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z56
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BU of 5z56 by Molmil
cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z57
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BU of 5z57 by Molmil
Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5T2A
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BU of 5t2a by Molmil
CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution
Descriptor: 18S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
1NUR
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BU of 1nur by Molmil
CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE
Descriptor: FKSG76, SULFATE ION
Authors:Zhang, X, Kurnasov, O.V, Karthikeyan, S, Grishin, N.V, Osterman, A.L, Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
5YZG
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BU of 5yzg by Molmil
The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y.
Deposit date:2017-12-14
Release date:2018-08-08
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of a human catalytic step I spliceosome
Science, 359, 2018
6AHD
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BU of 6ahd by Molmil
The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
Authors:Zhan, X, Yan, C, Zhang, X, Shi, Y.
Deposit date:2018-08-17
Release date:2018-11-14
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018

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