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5HBN
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BU of 5hbn by Molmil
ClpC N-terminal domain with bound phospho-arginine
Descriptor: ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
Authors:Suskiewicz, M.J, Clausen, T.
Deposit date:2016-01-01
Release date:2016-10-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature, 539, 2016
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
Descriptor: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
Authors:Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
Deposit date:2020-09-03
Release date:2021-08-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
Authors:Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
Deposit date:2020-09-08
Release date:2021-10-06
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
4OHY
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BU of 4ohy by Molmil
C. Elegans Clp1 bound to ssRNA dinucleotide GC, AMP-PNP, and Mg2+(inhibited substrate bound state)
Descriptor: MAGNESIUM ION, NONAETHYLENE GLYCOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OI4
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BU of 4oi4 by Molmil
Protein complex of Clp1 bound to ATP and Mg2+ with Pcf11deltaN454deltaC563 of S. cerevisiae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OI0
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BU of 4oi0 by Molmil
bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set I)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OHX
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BU of 4ohx by Molmil
C. Elegans Clp1 bound to ADP and Mg2+ (RNA released state)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OHZ
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BU of 4ohz by Molmil
bound to ssRNA tetranucleotide GAAA, ADP, and Mg2+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OHV
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BU of 4ohv by Molmil
C. Elegans Clp1 bound to AMP-PNP, and Mg2+
Descriptor: MAGNESIUM ION, NONAETHYLENE GLYCOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OHW
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BU of 4ohw by Molmil
C. Elegans Clp1 bound to ATP, and Mn2+(ATP-bound state)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OI2
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BU of 4oi2 by Molmil
C. Elegans Clp1 and ADP and Mg2+ (turnover state)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
4OI1
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BU of 4oi1 by Molmil
Clp1 bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set II)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A.
Deposit date:2014-01-18
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
1KY9
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BU of 1ky9 by Molmil
Crystal Structure of DegP (HtrA)
Descriptor: PROTEASE DO
Authors:Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T.
Deposit date:2002-02-04
Release date:2002-04-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
4KK3
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BU of 4kk3 by Molmil
YwlE arginine phosphatase - wildtype
Descriptor: Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION
Authors:Fuhrmann, J, Clausen, T.
Deposit date:2013-05-05
Release date:2013-07-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Cell Rep, 3, 2013
4KK4
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BU of 4kk4 by Molmil
YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine
Descriptor: Low molecular weight protein-tyrosine-phosphatase YwlE
Authors:Fuhrmann, J, Clausen, T.
Deposit date:2013-05-05
Release date:2013-07-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Cell Rep, 3, 2013
4C2E
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BU of 4c2e by Molmil
Crystal structure of the protease CtpB(S309A) present in a resting state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2H
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BU of 4c2h by Molmil
Crystal structure of the CtpB(V118Y) mutant
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
1C7N
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BU of 1c7n by Molmil
CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE COFACTOR
Descriptor: CYSTALYSIN, PYRIDOXAL-5'-PHOSPHATE
Authors:Krupka, H.I, Huber, R, Holt, S.C, Clausen, T.
Deposit date:2000-03-16
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
EMBO J., 19, 2000
1C7O
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BU of 1c7o by Molmil
CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE-L-AMINOETHOXYVINYLGLYCINE COMPLEX
Descriptor: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, CYSTALYSIN
Authors:Krupka, H.I, Huber, R, Holt, S.C, Clausen, T.
Deposit date:2000-03-16
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
EMBO J., 19, 2000
4C2D
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BU of 4c2d by Molmil
Crystal structure of the protease CtpB in an active state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2C
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BU of 4c2c by Molmil
Crystal structure of the protease CtpB in an active state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2F
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BU of 4c2f by Molmil
Crystal structure of the CtpB R168A mutant present in an active conformation
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2G
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BU of 4c2g by Molmil
Crystal structure of CtpB(S309A) in complex with a peptide having a Val-Pro-Ala C-terminus
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
1EG5
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BU of 1eg5 by Molmil
NIFS-LIKE PROTEIN
Descriptor: AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Kaiser, J.T, Clausen, T, Bourenkow, G.P, Bartunik, H.-D, Steinbacher, S, Huber, R.
Deposit date:2000-02-13
Release date:2000-04-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J.Mol.Biol., 297, 2000
4A8A
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BU of 4a8a by Molmil
Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme
Descriptor: LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
Deposit date:2011-11-20
Release date:2011-12-28
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (14.2 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012

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