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5LJK
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BU of 5ljk by Molmil
Crystal structure of human apo CRBP1
Descriptor: Retinol-binding protein 1, SODIUM ION
Authors:Zanotti, G, Vallese, F, Berni, R, Menozzi, I.
Deposit date:2016-07-18
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
J. Struct. Biol., 197, 2017
5LJE
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BU of 5lje by Molmil
Crystal structure of holo human CRBP1/K40L,Q108L mutant
Descriptor: RETINOL, Retinol-binding protein 1, SODIUM ION
Authors:Zanotti, G, Vallese, F, Berni, R, Menozzi, I.
Deposit date:2016-07-18
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
J. Struct. Biol., 197, 2017
7OH1
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BU of 7oh1 by Molmil
Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Descriptor: FAB TT110, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021
7OH0
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BU of 7oh0 by Molmil
Tetanus neurotoxin HC domain in complex with TT104-Fab1
Descriptor: Fab TT104, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021
3TLM
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BU of 3tlm by Molmil
Crystal Structure of Endoplasmic Reticulum Ca2+-ATPase (SERCA) From Bovine Muscle
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Sacchetto, R, Bertipaglia, I, Giannetti, S, Cendron, L, Mascarello, F, Damiani, E, Carafoli, E, Zanotti, G.
Deposit date:2011-08-30
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) from bovine muscle.
J.Struct.Biol., 178, 2012
4XFW
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BU of 4xfw by Molmil
Crystal structure of the monoclinic form of alpha-carbonic anhydrase from the human pathogen Helicobacter pylori
Descriptor: ACETIC ACID, Alpha-carbonic anhydrase, CHLORIDE ION, ...
Authors:Compostella, M.E, Vallese, F, Berto, P, Zanotti, G.
Deposit date:2014-12-29
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:Structure of alpha-carbonic anhydrase from the human pathogen Helicobacter pylori.
Acta Crystallogr.,Sect.F, 71, 2015
1F0Q
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BU of 1f0q by Molmil
CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF PROTEIN KINASE CK2 IN COMPLEX WITH THE NUCLEOTIDE COMPETITIVE INHIBITOR EMODIN
Descriptor: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, PROTEIN KINASE CK2, ALPHA SUBUNIT
Authors:Battistutta, R, Sarno, S, De Moliner, E, Papinutto, E, Zanotti, G, Pinna, L.A.
Deposit date:2000-05-17
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
J.Biol.Chem., 275, 2000
2G3V
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BU of 2g3v by Molmil
Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori
Descriptor: (UNK)(UNK)(UNK)(UNK)(UNK)(MSE)(UNK), CAG pathogenicity island protein 13
Authors:Cendron, L, Tasca, E, Angelini, A, Seydel, A, Battistutta, R, Montecucco, C, Zanotti, G.
Deposit date:2006-02-21
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of CagS from helicobacter pylori
To be Published
4MTC
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BU of 4mtc by Molmil
Crystal structure of human C53A DJ-1
Descriptor: 1,2-ETHANEDIOL, Protein DJ-1
Authors:Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L.
Deposit date:2013-09-19
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
4N12
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BU of 4n12 by Molmil
Crystal structure of human E18D DJ-1 in complex with Cu
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, Protein DJ-1
Authors:Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L.
Deposit date:2013-10-03
Release date:2014-03-05
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.478 Å)
Cite:DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
2RD3
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BU of 2rd3 by Molmil
Crystal structure of TenA homologue (HP1287) from Helicobacter pylori
Descriptor: Transcriptional regulator
Authors:Barison, N, Cendron, L, Trento, A, Angelini, A, Zanotti, G.
Deposit date:2007-09-21
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural and functional characterization of HP1287 from Helicobacter pylori demonstrates it is a TenA homologue
To be Published
4TSD
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BU of 4tsd by Molmil
Crystal structure of Helicobacter pylori HP1029
Descriptor: 1,2-ETHANEDIOL, HP1029, ZINC ION
Authors:Vallese, F, Percudani, R, Zanotti, G.
Deposit date:2014-06-18
Release date:2015-06-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The crystal structure of Helicobacter pylori HP1029 highlights the functional diversity of the sialic acid-related DUF386 family.
Febs J., 282, 2015
2FJC
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BU of 2fjc by Molmil
Crystal structure of antigen TpF1 from Treponema pallidum
Descriptor: Antigen TpF1, FE (III) ION
Authors:Thumiger, A, Polenghi, A, Papinutto, E, Battistutta, R, Montecucco, C, Zanotti, G.
Deposit date:2006-01-02
Release date:2006-01-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of antigen TpF1 from Treponema pallidum.
Proteins, 62, 2006
3KVD
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BU of 3kvd by Molmil
Crystal structure of the Neisseria meningitidis Factor H binding protein, fHbp (GNA1870) at 2.0 A resolution
Descriptor: Lipoprotein
Authors:Cendron, L, Veggi, D, Girardi, E, Zanotti, G.
Deposit date:2009-11-30
Release date:2010-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Acta Crystallogr.,Sect.F, 67, 2011
2G3X
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BU of 2g3x by Molmil
Crystal structure of Transthyretin mutant I84S at acidic pH
Descriptor: Transthyretin
Authors:Pasquato, N, Folli, C, Berni, R, Zanotti, G.
Deposit date:2006-02-21
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
J.Mol.Biol., 366, 2007
2G4G
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BU of 2g4g by Molmil
Crystal structure of human transthyretin at pH 4.6
Descriptor: Transthyretin
Authors:Pasquato, N, Folli, C, Berni, R, Zanotti, G.
Deposit date:2006-02-22
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
J.Mol.Biol., 366, 2007
2G4E
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BU of 2g4e by Molmil
Crystal structure of transthyretin mutant I84A at neutral pH
Descriptor: Transthyretin
Authors:Pasquato, N, Folli, C, Berni, R, Zanotti, G.
Deposit date:2006-02-22
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
J.Mol.Biol., 366, 2007
2G3Z
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BU of 2g3z by Molmil
Crystal structure of Transthyretin mutant I84A at low pH
Descriptor: Transthyretin
Authors:Pasquato, N, Folli, C, Berni, R, Zanotti, G.
Deposit date:2006-02-21
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
J.Mol.Biol., 366, 2007
6R66
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BU of 6r66 by Molmil
Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue
Descriptor: 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R67
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BU of 6r67 by Molmil
Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue
Descriptor: (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R68
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BU of 6r68 by Molmil
Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue
Descriptor: (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R6I
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BU of 6r6i by Molmil
Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue
Descriptor: 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-27
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.467 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R7G
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BU of 6r7g by Molmil
Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family
Descriptor: Coat protein, polyU RNA
Authors:Grinzato, A, Kandiah, E, Lico, C, Betti, C, Baschieri, S, Zanotti, G.
Deposit date:2019-03-28
Release date:2020-03-18
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family.
Nat.Chem.Biol., 16, 2020
4OW6
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BU of 4ow6 by Molmil
Crystal structure of Diphtheria Toxin at acidic pH
Descriptor: Diphtheria toxin
Authors:Leka, O, Vallese, F, Pirazzini, M, Berto, P, Montecucco, C, Zanotti, G.
Deposit date:2014-01-31
Release date:2014-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Diphtheria toxin conformational switching at acidic pH.
Febs J., 281, 2014
2B5S
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BU of 2b5s by Molmil
Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens
Descriptor: HEPTANE, LAURIC ACID, Non-specific lipid transfer protein, ...
Authors:Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, R.J, Zanotti, G.
Deposit date:2005-09-29
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens
J.Mol.Biol., 356, 2006

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