5LG3
 
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with chlorpromazine | | Descriptor: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Gamma-aminobutyric-acid receptor subunit beta-1 | | Authors: | Nys, M, Wijckmans, E, Farinha, A, Brams, M, Spurny, R, Ulens, C. | | Deposit date: | 2016-07-05 | | Release date: | 2016-10-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.567 Å) | | Cite: | Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5LID
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromopromazine | | Descriptor: | Cys-loop ligand-gated ion channel, bromopromazine | | Authors: | Nys, M, Wijckmans, E, Farinha, A, Brams, M, Spurny, R, Ulens, C. | | Deposit date: | 2016-07-14 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6CKF
 | | Structure of a new ShKT peptide from the sea anemone Oulactis sp: OspTx2a-p2 | | Descriptor: | OspTx2a-p2 | | Authors: | Sunanda, P, Krishnarjuna, B, Norton, R.S. | | Deposit date: | 2018-02-28 | | Release date: | 2019-03-06 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | Identification, chemical synthesis, structure, and function of a new KV1 channel blocking peptide from Oulactis sp.
Peptide Science, 110, 2018
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6CKD
 | | Structure of a new ShKT peptide from the sea anemone Oulactis sp: OspTx2a-p1 | | Descriptor: | OspTx2a-p1 | | Authors: | Sunanda, P, Krishnarjuna, B, Norton, R.S. | | Deposit date: | 2018-02-27 | | Release date: | 2019-02-27 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Identification, chemical synthesis, structure, and function of a new KV1 channel blocking peptide from Oulactis sp.
Peptide Science, 110, 2018
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6BTV
 | | Solution NMR structures for CcoTx-II | | Descriptor: | Beta-theraphotoxin-Cm1b | | Authors: | Agwa, A.J, Schroeder, C.I. | | Deposit date: | 2017-12-07 | | Release date: | 2018-05-09 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
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6BUC
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6BR0
 | | Solution NMR structure for CcoTx-I | | Descriptor: | Beta-theraphotoxin-Cm1a | | Authors: | Agwa, A.J, Schroeder, C.I. | | Deposit date: | 2017-11-29 | | Release date: | 2018-05-16 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
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2MQU
 | | Spatial structure of Hm-3, a membrane-active spider toxin affecting sodium channels | | Descriptor: | Neurotoxin Hm-3 | | Authors: | Myshkin, M.Y, Shenkarev, Z.O, Paramonov, A.S, Berkut, A.A, Grishin, E.V, Vassilevski, A.A. | | Deposit date: | 2014-06-27 | | Release date: | 2014-11-05 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
J. Biol. Chem., 290, 2015
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2KGH
 | | Solution structure of Brachyperma ruhnaui toxin 2 | | Descriptor: | Venom peptide 2 | | Authors: | Corzo, G, Bernard, C, Clement, H, Bosmans, F, Tygat, J, Possani, L.D, Darbon, H, Alagon, A. | | Deposit date: | 2009-03-12 | | Release date: | 2009-12-15 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochim.Biophys.Acta, 1794, 2009
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6AZA
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6BL9
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6ENA
 | | Nemertide alpha-1 | | Descriptor: | Nemertide alpha-1 | | Authors: | Jacobsson, E, Rosengren, K.J, Goransson, U. | | Deposit date: | 2017-10-04 | | Release date: | 2018-03-14 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Lineus longissimus, the longest animal on earth, expresses peptide toxins targeting voltage gated sodium channels
Sci Rep, 2018
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2M6A
 | | NMR spatial structure of the antimicrobial peptide Tk-Amp-X2 | | Descriptor: | Predicted protein | | Authors: | Usmanova, D.R, Mineev, K.S, Arseniev, A.S, Berkut, A.A, Oparin, P.B, Grishin, E.V, Vassilevski, A.A. | | Deposit date: | 2013-03-28 | | Release date: | 2014-04-02 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Structural similarity between defense peptide from wheat and scorpion neurotoxin permits rational functional design
J.Biol.Chem., 289, 2014
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