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2MQI
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BU of 2mqi by Molmil
human Fyn SH2 free state
Descriptor: Tyrosine-protein kinase Fyn
Authors:Huculeci, R, Buts, L, Lenaerts, T, VanNuland, N.
Deposit date:2014-06-20
Release date:2015-07-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity.
Structure, 24, 2016
3OEZ
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BU of 3oez by Molmil
crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain complexed with imatinib
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ACETATE ION, GLYCEROL, ...
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3OF0
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BU of 3of0 by Molmil
crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain
Descriptor: Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3QLG
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BU of 3qlg by Molmil
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib
Descriptor: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published
3QLF
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BU of 3qlf by Molmil
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5
Descriptor: 1-{4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published
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PDB entries from 2024-11-20

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