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8APM
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BU of 8apm by Molmil
Vaccinia virus DNA helicase D5 residues 323-785 hexamer with bound DNA processed in C1
Descriptor: DNA (5'-D(P*CP*CP*GP*AP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*TP*CP*GP*G)-3'), Primase D5
Authors:Burmeister, W.P, Hutin, S, Ling, W.L, Grimm, C, Schoehn, G.
Deposit date:2022-08-10
Release date:2022-11-09
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:The Vaccinia Virus DNA Helicase Structure from Combined Single-Particle Cryo-Electron Microscopy and AlphaFold2 Prediction.
Viruses, 14, 2022
6RIE
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BU of 6rie by Molmil
Structure of Vaccinia Virus DNA-dependent RNA polymerase co-transcriptional capping complex
Descriptor: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ...
Authors:Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P.
Deposit date:2019-04-23
Release date:2019-12-18
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Cell, 179, 2019
6RID
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BU of 6rid by Molmil
Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex
Descriptor: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ...
Authors:Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P.
Deposit date:2019-04-23
Release date:2019-12-18
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Cell, 179, 2019
2VY2
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BU of 2vy2 by Molmil
Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AG-I promoter
Descriptor: 5'-D(*AP*TP*TP*TP*AP*AP*TP*CP*CP*AP *AP*TP*GP*GP*TP*TP*AP*CP*AP*A)-3', PROTEIN LEAFY
Authors:Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W.
Deposit date:2008-07-16
Release date:2008-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins.
Embo J., 27, 2008
2VY1
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BU of 2vy1 by Molmil
Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AP1 promoter
Descriptor: 5'-D(*TP*TP*AP*CP*GP*GP*AP*CP*CP*AP *CP*TP*GP*GP*TP*CP*CP*TP*TP*CP)-3', PROTEIN LEAFY
Authors:Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W.
Deposit date:2008-07-16
Release date:2008-09-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins.
Embo J., 27, 2008
7O6R
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BU of 7o6r by Molmil
Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with 1H-Indazole
Descriptor: 1H-indazole, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Zehe, M, Grimm, C, Sotriffer, C.
Deposit date:2021-04-12
Release date:2022-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct.
Acs Chem.Biol., 2024
7ODI
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BU of 7odi by Molmil
Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with methanesulfonamide
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ...
Authors:Zehe, M, Grimm, C, Sotriffer, C.
Deposit date:2021-04-29
Release date:2022-06-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct.
Acs Chem.Biol., 2024
7ODB
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BU of 7odb by Molmil
Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with triazine-derivative
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-5-sulfanylidene-2H-1,2,4-triazin-3-one, GLYCEROL, ...
Authors:Zehe, M, Grimm, C, Sotriffer, C.
Deposit date:2021-04-29
Release date:2022-06-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct.
Acs Chem.Biol., 2024
7ODD
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BU of 7odd by Molmil
Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with tricine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ...
Authors:Zehe, M, Grimm, C, Sotriffer, C.
Deposit date:2021-04-29
Release date:2022-06-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.984 Å)
Cite:Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct.
Acs Chem.Biol., 2024
7BB3
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BU of 7bb3 by Molmil
Structure of S. pombe YG-box oligomer
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Survival motor neuron-like protein 1,Survival motor neuron-like protein 1
Authors:Veepaschit, J, Grimm, C, Fischer, U.
Deposit date:2020-12-16
Release date:2021-01-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.158 Å)
Cite:Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.
Nucleic Acids Res., 49, 2021
7BBL
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BU of 7bbl by Molmil
Structure of human Gemin6/Gemin7/Gemin8 trimeric complex
Descriptor: Gem-associated protein 6, Gem-associated protein 7, Gem-associated protein 8
Authors:Viswanathan, A, Grimm, C, Fischer, U.
Deposit date:2020-12-17
Release date:2021-01-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.
Nucleic Acids Res., 49, 2021
8C8H
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BU of 8c8h by Molmil
Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme
Descriptor: Core protein E11, DNA-directed RNA polymerase 133 kDa polypeptide, DNA-directed RNA polymerase 147 kDa polypeptide, ...
Authors:Grimm, G, Bartuli, J, Fischer, U.
Deposit date:2023-01-20
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme
To Be Published
8QAM
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BU of 8qam by Molmil
vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K
Descriptor: GLYCEROL, SULFATE ION, Uracil-DNA glycosylase
Authors:Tarbouriech, N, Burmeister, W.P.
Deposit date:2023-08-23
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus.
Plos Pathog., 20, 2024
8OUO
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BU of 8ouo by Molmil
Human TPC2 in Complex with Antagonist (S)-SG-094
Descriptor: (1S)-6-methoxy-2-methyl-7-phenoxy-1-[(4-phenoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
Authors:Chi, G, Pike, A.C.W, Maclean, E.M, Li, H, Mukhopadhyay, S.M.M, Bohstedt, T, Wang, D, McKinley, G, Fernandez-Cid, A, Duerr, K.
Deposit date:2023-04-24
Release date:2024-06-12
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
Structure, 32, 2024
2X6U
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BU of 2x6u by Molmil
Crystal structure of human TBX5 in the DNA-free form
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5
Authors:Stirnimann, C.U, Mueller, C.W.
Deposit date:2010-02-22
Release date:2010-04-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
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