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1FT8
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BU of 1ft8 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: TIP ASSOCIATING PROTEIN
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-09-12
Release date:2000-12-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
4IFD
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BU of 4ifd by Molmil
Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Exosome complex component CSL4, ...
Authors:Makino, D.L, Conti, E.
Deposit date:2012-12-14
Release date:2013-02-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
Nature, 495, 2013
1FO1
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BU of 1fo1 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: NUCLEAR RNA EXPORT FACTOR 1
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-08-24
Release date:2000-11-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
4JHK
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BU of 4jhk by Molmil
Crystal structure of Danio rerio SLIP1 in complex with SLBP
Descriptor: MIF4G domain-containing protein B, SULFATE ION, Sb:cb157 protein
Authors:von Moeller, H, Conti, E.
Deposit date:2013-03-05
Release date:2013-07-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.507 Å)
Cite:Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
Nucleic Acids Res., 41, 2013
4JHJ
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BU of 4jhj by Molmil
Crystal structure of Danio rerio Slip1 in complex with Dbp5
Descriptor: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast), MIF4G domain-containing protein B
Authors:Von Moeller, H, Conti, E.
Deposit date:2013-03-05
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
Nucleic Acids Res., 41, 2013
5OOQ
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BU of 5ooq by Molmil
Structure of the Mtr4 Nop53 Complex
Descriptor: ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION
Authors:Falk, S, Basquin, J, Conti, E.
Deposit date:2017-08-08
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
4Q8H
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BU of 4q8h by Molmil
Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase-RNase module
Descriptor: MAGNESIUM ION, PAB-dependent poly(A)-specific ribonuclease subunit PAN2
Authors:Schaefer, I.B, Conti, E.
Deposit date:2014-04-27
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
4Q8G
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BU of 4q8g by Molmil
Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase
Descriptor: PAB-dependent poly(A)-specific ribonuclease subunit PAN2, ZINC ION
Authors:Schaefer, I.B, Conti, E.
Deposit date:2014-04-27
Release date:2014-06-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
4TXD
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BU of 4txd by Molmil
Crystal structure of Thermofilum pendens Csc2
Descriptor: Csc2, ZINC ION
Authors:Hrle, A, Conti, E.
Deposit date:2014-07-03
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.
Rna Biol., 11, 2014
4U4C
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BU of 4u4c by Molmil
The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities
Descriptor: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ...
Authors:Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E.
Deposit date:2014-07-23
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities.
Mol.Cell, 55, 2014
6H25
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BU of 6h25 by Molmil
Human nuclear RNA exosome EXO-10-MPP6 complex
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Gerlach, P, Schuller, J.M, Falk, S, Basquin, J, Conti, E.
Deposit date:2018-07-13
Release date:2018-08-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Distinct and evolutionary conserved structural features of the human nuclear exosome complex.
Elife, 7, 2018
4ZRL
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BU of 4zrl by Molmil
Structure of the non canonical Poly(A) polymerase complex GLD-2 - GLD-3
Descriptor: CHLORIDE ION, Defective in germ line development protein 3, Poly(A) RNA polymerase gld-2
Authors:Nakel, K, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2015-05-12
Release date:2015-07-08
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3.
Proc.Natl.Acad.Sci.USA, 112, 2015
2BR2
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BU of 2br2 by Molmil
RNase PH core of the archaeal exosome
Descriptor: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2
Authors:lorentzen, E, Fribourg, S, Conti, E.
Deposit date:2005-04-30
Release date:2005-06-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits.
Nat.Struct.Mol.Biol., 12, 2005
1A0E
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BU of 1a0e by Molmil
XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA
Descriptor: COBALT (II) ION, XYLOSE ISOMERASE
Authors:Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D.
Deposit date:1997-11-28
Release date:1998-06-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
2C37
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BU of 2c37 by Molmil
RNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA
Descriptor: 5-O-phosphono-beta-D-ribofuranose, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-04
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
1OL6
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BU of 1ol6 by Molmil
Structure of unphosphorylated D274N mutant of Aurora-A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, SERINE/THREONINE KINASE 6
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle.
Mol.Cell, 12, 2003
1OL5
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BU of 1ol5 by Molmil
Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ...
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OL7
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BU of 1ol7 by Molmil
Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SERINE/THREONINE KINASE 6
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OF5
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BU of 1of5 by Molmil
Crystal structure of Mex67-Mtr2
Descriptor: MERCURY (II) ION, MRNA EXPORT FACTOR MEX67, MRNA TRANSPORT REGULATOR MTR2
Authors:Fribourg, S, Conti, E.
Deposit date:2003-04-08
Release date:2003-07-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15.
EMBO Rep., 4, 2003
2C38
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BU of 2c38 by Molmil
RNase PH core of the archaeal exosome in complex with A5 RNA
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-04
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
8BFI
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BU of 8bfi by Molmil
human CNOT1-CNOT10-CNOT11 module
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
Authors:Basquin, J, Ozgur, S, Conti, E.
Deposit date:2022-10-26
Release date:2022-12-28
Last modified:2023-02-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
8BFH
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BU of 8bfh by Molmil
CNOT11
Descriptor: CCR4-NOT transcription complex subunit 11
Authors:Basquin, J, Ozgur, S, Conti, E.
Deposit date:2022-10-26
Release date:2022-12-28
Last modified:2023-02-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
8BFJ
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BU of 8bfj by Molmil
CNOT11-GGNBP2 complex
Descriptor: 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2
Authors:Basquin, J, Ozgur, S, Conti, E.
Deposit date:2022-10-26
Release date:2022-12-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
2C39
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BU of 2c39 by Molmil
RNase PH core of the archaeal exosome in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, PROBABLE EXOSOME COMPLEX EXONUCLEASE 2
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-05
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
5C0X
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BU of 5c0x by Molmil
Structure of a 12-subunit nuclear exosome complex bound to structured RNA
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Makino, D.L, Conti, E.
Deposit date:2015-06-12
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015

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