3PBX
 
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3GNK
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3GOO
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3GOM
 | | Barium bound to the Holliday junction sequence d(TCGGCGCCGA)4 | | Descriptor: | 5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3', BARIUM ION | | Authors: | Naseer, A, Cardin, C.J. | | Deposit date: | 2009-03-19 | | Release date: | 2009-04-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3GOJ
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6RSO
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2GWA
 | | Crystal Structure of a Complex Formed Between the DNA Holliday Junction and a Bis-Acridine Molecule. | | Descriptor: | 5'-D(*Tp*Cp*Gp*Gp*Tp*Ap*Cp*Cp*Gp*A)-3', 9,9'-(HEXANE-1,6-DIYLDIIMINO)BIS{N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE}, SPERMINE | | Authors: | Brogden, A.L, Hopcroft, N.H, Cardin, C.J, Searcey, M. | | Deposit date: | 2006-05-04 | | Release date: | 2006-06-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Ligand bridging of the DNA Holliday junction: molecular recognition of a stacked-X four-way junction by a small molecule.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2GJB
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2GB9
 | | d(CGTACG)2 crosslinked bis-acridine complex | | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', 9,9'-(HEXANE-1,6-DIYLDIIMINO)BIS{N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE}, STRONTIUM ION | | Authors: | Hopcroft, N.H, Brogden, A.L, Searcey, M, Cardin, C.J. | | Deposit date: | 2006-03-10 | | Release date: | 2006-04-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative.
Nucleic Acids Res., 34, 2006
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6RSP
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367D
 | | 1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX | | Descriptor: | 5'-D(*CP*GP*(BRU)P*AP*CP*G)-3', 5-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE, BROMIDE ION | | Authors: | Todd, A.K, Adams, A, Thorpe, J.H, Denny, W.A, Cardin, C.J. | | Deposit date: | 1997-12-19 | | Release date: | 2003-03-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethlyamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5Br-U)ACG)2 at 1.3-angstrom resolution
J.Med.Chem., 42, 1999
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344D
 | | DETERMINATION BY MAD-DM OF THE STRUCTURE OF THE DNA DUPLEX D(ACGTACG(5-BRU))2 AT 1.46A AND 100K | | Descriptor: | DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*(BRU))-3') | | Authors: | Todd, A.R, Adams, A, Powell, H.R, Cardin, C.J. | | Deposit date: | 1997-08-04 | | Release date: | 1997-09-26 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | Determination by MAD-DM of the structure of the DNA duplex d[ACGTACG(5-BrU)]2 at 1.46 A and 100 K.
Acta Crystallogr.,Sect.D, 55, 1999
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366D
 | | 1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX | | Descriptor: | 6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE, DNA (5'-D(*CP*GP*(BRU)P*AP*CP*G)-3') | | Authors: | Todd, A.K, Adams, A, Thorpe, J.H, Denny, W.A, Cardin, C.J. | | Deposit date: | 1997-12-19 | | Release date: | 1999-04-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution.
J.Med.Chem., 42, 1999
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4IZQ
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1M6G
 | | Structural Characterisation of the Holliday Junction TCGGTACCGA | | Descriptor: | 5'-D(*TP*CP*GP*GP*TP*AP*CP*CP*GP*A)-3', STRONTIUM ION | | Authors: | Thorpe, J.H, Gale, B.C, Teixeira, S.C.M, Cardin, C.J. | | Deposit date: | 2002-07-16 | | Release date: | 2003-05-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.652 Å) | | Cite: | Conformational and hydration effects of site-selective sodium, calcium and
strontium ion binding to the DNA Holliday junction structure
d(TCGGTACCGA)(4)
J.Mol.Biol., 327, 2003
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1L4J
 | | Holliday Junction TCGGTACCGA with Na and Ca Binding Sites. | | Descriptor: | 5'-D(*TP*CP*GP*GP*TP*AP*CP*CP*GP*A)-3', CALCIUM ION, SODIUM ION | | Authors: | Thorpe, J.H, Gale, B.C, Teixeira, S.C.M, Cardin, C.J. | | Deposit date: | 2002-03-05 | | Release date: | 2003-03-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Conformational and Hydration Effects of Site-selective Sodium, Calcium and
Strontium Ion Binding to the DNA Holliday Junction Structure
d(TCGGTACCGA)4
J.Mol.Biol., 327, 2003
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1M69
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1MF5
 | | GCATGCT Quadruplex | | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT HEXAMMINE(III) | | Authors: | Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Cardin, C.J. | | Deposit date: | 2002-08-09 | | Release date: | 2003-02-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Crystal structure of the complementary quadruplex formed by d(GCATGCT) at atomic
resolution
Nucleic Acids Res., 31, 2003
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1JUC
 | | Crystal Structure Analysis of a Holliday Junction Formed by CCGGTACCGG | | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3' | | Authors: | Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Cardin, C.J. | | Deposit date: | 2001-08-24 | | Release date: | 2002-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural characterization of a new crystal form of the four-way Holliday junction formed by the DNA sequence d(CCGGTACCGG)2: sequence versus lattice?
Acta Crystallogr.,Sect.D, 58, 2002
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1K2L
 | | STRUCTURAL CHARACTERIZATION OF BISINTERCALATION IN HIGHER-ORDER DNA AT A JUNCTION-LIKE QUADRUPLEX | | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', BIS-(9-OCTYLAMINO(2-DIMETHYLAMINOETHYL)ACRIDINE-4-CARBOXAMIDE, COBALT (II) ION | | Authors: | Teixeira, S.C.M, Thorpe, J.H, Todd, A.K, Powell, H.R, Adams, A, Wakelin, L.P.G, Denny, W.A, Cardin, C.J. | | Deposit date: | 2001-09-28 | | Release date: | 2002-10-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Characterisation of Bisintercalation in Higher-order DNA at a Junction-like Quadruplex
J.MOL.BIOL., 323, 2002
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8OYR
 | | DNA Major Groove Binding by lambda-[Ru(phen)2(phi)]2+ | | Descriptor: | DNA (5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3'), STRONTIUM ION, ruthenium polypyridyl complex (lambda enantiomer) | | Authors: | Prieto-Otoya, T.D, Cardin, C.J, McQuaid, K.T, Paterson, N.G. | | Deposit date: | 2023-05-05 | | Release date: | 2024-03-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Probing a Major DNA Weakness: Resolving the Groove and Sequence Selectivity of the Diimine Complex Lambda-[Ru(phen) 2 phi] 2.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8P6B
 | | Ruthenium complex bound to an antiparallel G-quadruplex | | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION, Ruthenium bis-(phenanthroline) 12,17-dihydro-naphthodipyridophenazine-12,17-dione | | Authors: | McQuaid, K.T, Cardin, C.J. | | Deposit date: | 2023-05-25 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Ruthenium complex bound to an antiparallel G-quadruplex
To Be Published
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8PJL
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8PIP
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8BAG
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