3DXD
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5E4W
| Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail | Descriptor: | CALCIUM ION, GLYCEROL, Inner membrane protein ALBINO3, ... | Authors: | Horn, A, Ahmed, Y.L, Wild, K, Sinning, I. | Deposit date: | 2015-10-07 | Release date: | 2015-12-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015
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3DXE
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4EV1
| Anabaena Tic22 (protein transport) | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Anabena Tic22, ... | Authors: | Koenig, P, Schleiff, E, Sinning, I, Tews, I. | Deposit date: | 2012-04-25 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Functional conservation of Tic22 in cyanobacterial outer membrane protein assembly and chloroplast translocation. TO BE PUBLISHED
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4P3G
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2J28
| MODEL OF E. COLI SRP BOUND TO 70S RNCS | Descriptor: | 23S RIBOSOMAL RNA, 4.5S SIGNAL RECOGNITION PARTICLE RNA, 50S ribosomal protein L11, ... | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | Deposit date: | 2006-08-16 | Release date: | 2006-11-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Following the Signal Sequence from Ribosomal Tunnel Exit to Signal Recognition Particle Nature, 444, 2006
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1GSD
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4P3E
| Structure of the human SRP S domain | Descriptor: | MAGNESIUM ION, SRP RNA (124-mer), Signal recognition particle 19 kDa protein, ... | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | Deposit date: | 2014-03-07 | Release date: | 2014-04-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation. Science, 344, 2014
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2J37
| MODEL OF MAMMALIAN SRP BOUND TO 80S RNCS | Descriptor: | 60S RIBOSOMAL PROTEIN L23, RIBOSOMAL PROTEIN L31, RIBOSOMAL PROTEIN L35, ... | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | Deposit date: | 2006-08-18 | Release date: | 2006-11-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature, 444, 2006
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1GSF
| GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID | Descriptor: | ETHACRYNIC ACID, GLUTATHIONE TRANSFERASE A1-1 | Authors: | L'Hermite, G, Sinning, I, Cameron, A.D, Jones, T.A. | Deposit date: | 1995-06-09 | Release date: | 1995-09-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate. Structure, 3, 1995
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4P3F
| Structure of the human SRP68-RBD | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Signal recognition particle subunit SRP68 | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | Deposit date: | 2014-03-07 | Release date: | 2014-04-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation. Science, 344, 2014
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1FTS
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1J8Y
| Signal Recognition Particle conserved GTPase domain from A. ambivalens T112A mutant | Descriptor: | SIGNAL RECOGNITION 54 KDA PROTEIN | Authors: | Montoya, G, te Kaat, K, Moll, R, Schaerfer, G, Sinning, I. | Deposit date: | 2001-05-23 | Release date: | 2001-06-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex. Structure Fold.Des., 8, 2000
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7Q73
| Structure of Pla1 apo | Descriptor: | GLYCEROL, Poly(A) polymerase pla1 | Authors: | Soni, K, Wild, K, Sinning, I. | Deposit date: | 2021-11-09 | Release date: | 2022-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
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7Q74
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7OLD
| Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OLC
| Thermophilic eukaryotic 80S ribosome at idle POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OVU
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7OVV
| Crystal structure of the Arabidopsis thaliana thialysine acetyltransferase AtNATA2 | Descriptor: | Probable acetyltransferase NATA1-like, [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate | Authors: | Layer, D, Kopp, J, Sinning, I. | Deposit date: | 2021-06-15 | Release date: | 2022-12-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into the Arabidopsis thaliana thialysine acetyltransferase AtNATA2 To Be Published
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3UI2
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5L3W
| Structure of the crenarchaeal FtsY GTPase bound to GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle receptor FtsY | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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4ADS
| Crystal structure of plasmodial PLP synthase complex | Descriptor: | PDX2 PROTEIN, PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, ... | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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4ADT
| Crystal structure of plasmodial PLP synthase | Descriptor: | PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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4ADU
| Crystal structure of plasmodial PLP synthase with bound R5P intermediate | Descriptor: | 1,2-ETHANEDIOL, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE, ... | Authors: | Guedez, G, Sinning, I, Tews, I. | Deposit date: | 2012-01-03 | Release date: | 2012-01-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
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4D2U
| Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP) | Descriptor: | CHAPERONE PROTEIN CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-13 | Release date: | 2014-06-04 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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