2QAS
 
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1ZSZ
 | | Crystal structure of a computationally designed SspB heterodimer | | Descriptor: | MAGNESIUM ION, Stringent starvation protein B homolog | | Authors: | Bolon, D.N, Grant, R.A, Baker, T.A, Sauer, R.T. | | Deposit date: | 2005-05-25 | | Release date: | 2005-08-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specificity versus stability in computational protein design.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1YFN
 | | Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex | | Descriptor: | Sigma-E factor negative regulatory protein, Stringent starvation protein B | | Authors: | Levchenko, I, Grant, R.A, Flynn, J.M, Sauer, R.T, Baker, T.A. | | Deposit date: | 2005-01-03 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
Nat.Struct.Mol.Biol., 12, 2005
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3LGU
 | | Y162A mutant of the DegS-deltaPDZ protease | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGY
 | | R178A mutant of the DegS-deltaPDZ protease | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGV
 | | H198P mutant of the DegS-deltaPDZ protease | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.734 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGW
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3LGI
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3LGT
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3LH3
 | | DFP modified DegS delta PDZ | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3O1F
 | | P1 crystal form of E. coli ClpS at 1.4 A resolution | | Descriptor: | ATP-dependent Clp protease adapter protein clpS | | Authors: | Roman-Hernandez, G, Hou, J.Y, Grant, R.A, Sauer, R.T, Baker, T.A. | | Deposit date: | 2010-07-21 | | Release date: | 2011-07-27 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease.
Mol.Cell, 43, 2011
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3O2H
 | | E. coli ClpS in complex with a Leu N-end rule peptide | | Descriptor: | ATP-dependent Clp protease adaptor protein ClpS, DNA protection during starvation protein | | Authors: | Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A. | | Deposit date: | 2010-07-22 | | Release date: | 2011-12-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol.Cell, 43, 2011
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3O2O
 | | Structure of E. coli ClpS ring complex | | Descriptor: | ATP-dependent Clp protease adaptor protein ClpS | | Authors: | Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A. | | Deposit date: | 2010-07-22 | | Release date: | 2011-12-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol.Cell, 43, 2011
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3O2B
 | | E. coli ClpS in complex with a Phe N-end rule peptide | | Descriptor: | ATP-dependent Clp protease adaptor protein ClpS, CHLORIDE ION, Phe N-end rule peptide, ... | | Authors: | Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A. | | Deposit date: | 2010-07-22 | | Release date: | 2011-12-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol.Cell, 43, 2011
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3OTP
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6PP7
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6POD
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PP5
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PPE
 | | ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PO3
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6POS
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PO1
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PP6
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PP8
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PXI
 | | The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | | Deposit date: | 2019-07-26 | | Release date: | 2020-07-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.447 Å) | | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
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