6PO1
 
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
|
|
6PP8
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
|
|
6PP6
 | | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
|
|
6PXI
 | | The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | | Deposit date: | 2019-07-26 | | Release date: | 2020-07-29 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (3.447 Å) | | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
|
|
6PXL
 | | 3.74 Angstroms resolution structure of HlsU with an axial-channel plug | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, MAGNESIUM ION, ... | | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | | Deposit date: | 2019-07-26 | | Release date: | 2020-07-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.741 Å) | | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
|
|
6PXK
 | | 3.65 Angstroms resolution structure of HslU with an axial-channel plug | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ... | | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | | Deposit date: | 2019-07-26 | | Release date: | 2020-07-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.647 Å) | | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
|
|
4I34
 | | Crystal Structure of W-W-W ClpX Hexamer | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | | Deposit date: | 2012-11-23 | | Release date: | 2013-05-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (4.1218 Å) | | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
|
|
4I81
 | | Crystal Structure of ATPgS bound ClpX Hexamer | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SULFATE ION | | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | | Deposit date: | 2012-12-01 | | Release date: | 2013-05-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.8182 Å) | | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
|
|
4I4L
 | | Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | | Deposit date: | 2012-11-27 | | Release date: | 2013-05-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.6981 Å) | | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
|
|
1YFN
 | | Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex | | Descriptor: | Sigma-E factor negative regulatory protein, Stringent starvation protein B | | Authors: | Levchenko, I, Grant, R.A, Flynn, J.M, Sauer, R.T, Baker, T.A. | | Deposit date: | 2005-01-03 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
Nat.Struct.Mol.Biol., 12, 2005
|
|
1ZSZ
 | | Crystal structure of a computationally designed SspB heterodimer | | Descriptor: | MAGNESIUM ION, Stringent starvation protein B homolog | | Authors: | Bolon, D.N, Grant, R.A, Baker, T.A, Sauer, R.T. | | Deposit date: | 2005-05-25 | | Release date: | 2005-08-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specificity versus stability in computational protein design.
Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
4YKA
 | | The structure of Agrobacterium tumefaciens ClpS2 in complex with L-tyrosinamide | | Descriptor: | ATP-dependent Clp protease adapter protein ClpS 2, L-TYROSINAMIDE, SULFATE ION | | Authors: | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | | Deposit date: | 2015-03-04 | | Release date: | 2016-01-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Structural Basis of an N-Degron Adaptor with More Stringent Specificity.
Structure, 24, 2016
|
|
4YJX
 | | The structure of Agrobacterium tumefaciens ClpS2 bound to L-phenylalaninamide | | Descriptor: | ATP-dependent Clp protease adapter protein ClpS 2, PHENYLALANINE AMIDE, SULFATE ION | | Authors: | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | | Deposit date: | 2015-03-03 | | Release date: | 2016-01-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.547 Å) | | Cite: | Structural Basis of an N-Degron Adaptor with More Stringent Specificity.
Structure, 24, 2016
|
|
4YJM
 | |
2QAZ
 | |
2QF0
 | |
2QAS
 | |
2QF3
 | | Structure of the delta PDZ truncation of the DegS protease | | Descriptor: | PHOSPHATE ION, Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2007-06-26 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Allosteric activation of DegS, a stress sensor PDZ protease.
Cell(Cambridge,Mass.), 131, 2007
|
|
2QGR
 | |
4U0G
 | | Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist | | Descriptor: | ADEP-2B5Me, ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, ... | | Authors: | Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T. | | Deposit date: | 2014-07-11 | | Release date: | 2014-10-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.1978 Å) | | Cite: | Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4U0H
 | | Crystal Structure of M. tuberculosis ClpP1P1 | | Descriptor: | ATP-dependent Clp protease proteolytic subunit 1, SULFATE ION | | Authors: | Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T. | | Deposit date: | 2014-07-11 | | Release date: | 2014-10-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2479 Å) | | Cite: | Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2RCE
 | |
5JI2
 | | HslU L199Q in HslUV complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | | Authors: | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | | Deposit date: | 2016-04-21 | | Release date: | 2016-11-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.307 Å) | | Cite: | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
|
|
5JI3
 | | HslUV complex | | Descriptor: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV | | Authors: | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | | Deposit date: | 2016-04-21 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
|
|
3ES2
 | |
