5OFV
 
 | | Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-fluoro-2-methylbenzoic acid | | Descriptor: | 5-fluoranyl-2-methyl-benzoic acid, D-3-phosphoglycerate dehydrogenase | | Authors: | Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. | | Deposit date: | 2017-07-11 | | Release date: | 2017-08-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.
Oncotarget, 9, 2018
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7NJW
 | | Mycobacterium smegmatis ATP synthase Fo combined class 3 | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKJ
 | | Mycobacterium smegmatis ATP synthase F1 state 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.17 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJK
 | | Mycobacterium smegmatis ATP synthase state 1a | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJU
 | | Mycobacterium smegmatis ATP synthase Fo combined class 1 | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5NXB
 | | Mouse galactocerebrosidase in complex with saposin A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Graham, S.C, Hill, C.H, Deane, J.E. | | Deposit date: | 2017-05-09 | | Release date: | 2017-05-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure.
Nat Commun, 9, 2018
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7NKH
 | | Mycobacterium smegmatis ATP synthase F1 state 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJR
 | | Mycobacterium smegmatis ATP synthase state 3b | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJY
 | | Mycobacterium smegmatis ATP synthase Fo combined class 5 | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKK
 | | Mycobacterium smegmatis ATP synthase rotor state 2 | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NL9
 | | Mycobacterium smegmatis ATP synthase Fo state 3 | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-22 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJL
 | | Mycobacterium smegmatis ATP synthase state 1b | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJN
 | | Mycobacterium smegmatis ATP synthase state 1d | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJS
 | | Mycobacterium smegmatis ATP synthase state 3c | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.46 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5NZP
 | | Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-Hydroxybenzisoxazole | | Descriptor: | 1,2-benzoxazol-3-ol, D-3-phosphoglycerate dehydrogenase | | Authors: | Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. | | Deposit date: | 2017-05-14 | | Release date: | 2017-06-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.
Oncotarget, 9, 2018
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7NJT
 | | Mycobacterium smegmatis ATP synthase Fo combined all classes | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJM
 | | Mycobacterium smegmatis ATP synthase state 1c | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJX
 | | Mycobacterium smegmatis ATP synthase Fo combined class 4 | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.32 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKB
 | | Mycobacterium smegmatis ATP synthase rotor state 1 | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKQ
 | | Mycobacterium smegmatis ATP synthase b-delta state 3 | | Descriptor: | ATP synthase subunit alpha, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJQ
 | | Mycobacterium smegmatis ATP synthase state 3a | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKP
 | | Mycobacterium smegmatis ATP synthase Fo state 2 | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-18 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.06 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NK7
 | | Mycobacterium smegmatis ATP synthase F1 state 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.11 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJV
 | | Mycobacterium smegmatis ATP synthase Fo combined class 2 | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJP
 | | Mycobacterium smegmatis ATP synthase state 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-10-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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