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8RZU
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BU of 8rzu by Molmil
Structure of human SETD2 L1609P mutant in complex with SAM and H3K36M peptide
Descriptor: Histone H3, Histone-lysine N-methyltransferase SETD2, S-ADENOSYLMETHIONINE, ...
Authors:Mechaly, A.E, Michail, C, Haouz, A, Rodrigues-Lima, F.
Deposit date:2024-02-13
Release date:2025-03-05
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structure of human SETD2 L1609P mutant in complex with SAM and H3K36M peptide
To Be Published
8SP7
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BU of 8sp7 by Molmil
LINE-1 retrotransposon endonuclease domain complex with tranexamic acid
Descriptor: LINE-1 retrotransposon endonuclease, SULFATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:D'Ordine, A.M, Jogl, G, Sedivy, J.M.
Deposit date:2023-05-02
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease.
Nat Commun, 15, 2024
9FHT
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BU of 9fht by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex hexaguluronic acid at pH 3.5
Descriptor: Alginate lyase family protein, SULFATE ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FI4
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BU of 9fi4 by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant Q173N at pH 8
Descriptor: Alginate lyase family protein
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9CXP
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BU of 9cxp by Molmil
Cyan thermostable protein (CTP) 0.75 at pH 7.4
Descriptor: Cyan thermostable protein 0.75
Authors:Jurkowski, A.J, DeVore, N.M.
Deposit date:2024-07-31
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cyan Thermal Proteins Derived From Thermal Green Protein.
Proteins, 2025
9FI5
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BU of 9fi5 by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant Y298F in complex tetramannuronic acid at pH 3.5
Descriptor: Alginate lyase family protein, SULFATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9QEM
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BU of 9qem by Molmil
Crystal structure of YTHDF2 in complex with compound 3 (AI-DF2-11)
Descriptor: 5-[[(3-methoxyphenyl)amino]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione, CHLORIDE ION, GLYCEROL, ...
Authors:Nai, F, Invernizzi, A, Caflisch, A.
Deposit date:2025-03-10
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Discovery of YTHDF2 Ligands by Fragment-Based Design
Acs Bio Med Chem Au, 2025
9QEO
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BU of 9qeo by Molmil
Crystal structure of YTHDF2 in complex with compound 5 (AI-DF2-36)
Descriptor: 2-(methylamino)pyridine-3-carboxamide, CHLORIDE ION, GLYCEROL, ...
Authors:Nai, F, Invernizzi, A, Caflisch, A.
Deposit date:2025-03-10
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Discovery of YTHDF2 Ligands by Fragment-Based Design
Acs Bio Med Chem Au, 2025
9QFL
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BU of 9qfl by Molmil
Crystal structure of YTHDF2 in complex with compound 15 (AI-DF2-68)
Descriptor: 6-sulfanylidene-1,7-dihydropyrazolo[3,4-d]pyrimidin-4-one, GLYCEROL, SULFATE ION, ...
Authors:Nai, F, Invernizzi, A, Caflisch, A.
Deposit date:2025-03-11
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of YTHDF2 Ligands by Fragment-Based Design
Acs Bio Med Chem Au, 2025
9DR9
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BU of 9dr9 by Molmil
Binary product complex of DNA polymerase iota with DNA
Descriptor: DNA (5'-D(P*AP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*CP*T)-3'), DNA polymerase iota
Authors:Frevert, Z, Reusch, D, Freudenthal, B, Washington, M.T.
Deposit date:2024-09-25
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Visualizing DNA polymerase iota catalyze Hoogsteen-directed DNA synthesis
Nat Commun, 16, 2025
9C23
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BU of 9c23 by Molmil
Cyan thermostable protein (CTP) 1.0 at pH 6.5
Descriptor: Cyan thermostable protein 1.0
Authors:Jurkowski, A.J, DeVore, N.M.
Deposit date:2024-05-30
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cyan Thermal Proteins Derived From Thermal Green Protein.
Proteins, 2025
9C25
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BU of 9c25 by Molmil
Cyan thermostable protein (CTP) 1.0 at pH 8.5
Descriptor: Cyan thermostable protein 1.0, GLYCEROL
Authors:Jurkowski, A.J, Criblez, T.A, DeVore, N.M.
Deposit date:2024-05-30
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cyan Thermal Proteins Derived From Thermal Green Protein.
Proteins, 2025
9C26
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BU of 9c26 by Molmil
Cyan thermostable protein (CTP) 0.5 at pH 6.5
Descriptor: Cyan thermostable protein 0.5
Authors:Jurkowski, A.J, Brown, A, DeVore, N.M.
Deposit date:2024-05-30
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyan Thermal Proteins Derived From Thermal Green Protein.
Proteins, 2025
9DDR
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BU of 9ddr by Molmil
Ternary substrate complex of DNA polymerase iota with DNA (template A), Ca2+, and dTTP
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ...
Authors:Frevert, Z, Reusch, D, Freudenthal, B, Washington, M.T.
Deposit date:2024-08-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Visualizing DNA polymerase iota catalyze Hoogsteen-directed DNA synthesis
Nat Commun, 16, 2025
9DRB
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BU of 9drb by Molmil
Binary complex of DNA polymerase iota with product DNA
Descriptor: DNA (5'-D(P*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*CP*T)-3'), DNA polymerase iota
Authors:Frevert, Z, Reusch, D, Freudenthal, B, Washington, M.T.
Deposit date:2024-09-25
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Visualizing DNA polymerase iota catalyze Hoogsteen-directed DNA synthesis
Nat Commun, 16, 2025
9DRC
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BU of 9drc by Molmil
Ternary substrate complex of DNA polymerase iota R71A mutant with DNA (template A) and dTTP
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ...
Authors:Frevert, Z, Reusch, D, Freudenthal, B, Washington, M.T.
Deposit date:2024-09-25
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Visualizing DNA polymerase iota catalyze Hoogsteen-directed DNA synthesis
Nat Commun, 16, 2025
9NRC
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BU of 9nrc by Molmil
TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2025-03-14
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:A TMPRSS6-inhibiting mAb improves disease in a beta-thalassemia mouse model and reduces iron in healthy humans.
JCI Insight, 10, 2025
9FHU
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BU of 9fhu by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex hexamannuluronic acid at pH 3.5
Descriptor: Alginate lyase family protein, SULFATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FHW
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BU of 9fhw by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex tetraguluronic acid at pH 8
Descriptor: Alginate lyase family protein, SULFATE ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FHV
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BU of 9fhv by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex pentasaccharide (ManGul)3 at pH 3.5
Descriptor: Alginate lyase family protein, SULFATE ION, beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FHX
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BU of 9fhx by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex tetramannuronic acid at pH 8
Descriptor: Alginate lyase family protein, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FHY
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BU of 9fhy by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex with an unsaturated mannuronic acid tetramer at pH 3.5
Descriptor: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase family protein, SULFATE ION
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FHZ
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BU of 9fhz by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex unsaturated guluronic acid tetramer at pH 3.5
Descriptor: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, Alginate lyase family protein, ...
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FI0
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BU of 9fi0 by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant D108N
Descriptor: Alginate lyase family protein
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025
9FI2
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BU of 9fi2 by Molmil
Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant N242A at pH 3.5
Descriptor: Alginate lyase family protein
Authors:Tandrup, T, Wilkens, C.
Deposit date:2024-05-28
Release date:2025-07-09
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota.
J.Am.Chem.Soc., 2025

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PDB entries from 2025-07-09

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