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8CP7
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BU of 8cp7 by Molmil
Structure of the disulfide-locked substrate binding protein HiSiaP.
Descriptor: N-acetyl-beta-neuraminic acid, Sialic acid-binding periplasmic protein SiaP, ZINC ION
Authors:Kim, Y, Peter, M.F, Hagelueken, G.
Deposit date:2023-03-02
Release date:2023-12-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP.
Nat Commun, 15, 2024
6Z3C
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BU of 6z3c by Molmil
High resolution structure of RgNanOx
Descriptor: CITRATE ANION, Gfo/Idh/MocA family oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Naismith, J.H, Lee, M.O.
Deposit date:2020-05-19
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria.
J.Biol.Chem., 295, 2020
7QE5
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BU of 7qe5 by Molmil
Structure of the membrane domains of the sialic acid TRAP transporter HiSiaQM from Haemophilus influenzae
Descriptor: Megabody3, Sialic acid TRAP transporter permease protein SiaT
Authors:Peter, M.F, Hagelueken, G.
Deposit date:2021-12-01
Release date:2022-07-27
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 13, 2022
6H76
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BU of 6h76 by Molmil
SiaP in complex with Neu5Ac (RT)
Descriptor: CESIUM ION, CHLORIDE ION, N-acetyl-beta-neuraminic acid, ...
Authors:Fischer, M, Darby, J.F, Brannigan, J.A, Turkenburg, J, Hubbard, R.E.
Deposit date:2018-07-30
Release date:2019-08-14
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Water Networks Can Determine the Affinity of Ligand Binding to Proteins.
J.Am.Chem.Soc., 141, 2019
6H75
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BU of 6h75 by Molmil
SiaP A11N in complex with Neu5Ac (RT)
Descriptor: N-acetyl-beta-neuraminic acid, Sialic acid-binding periplasmic protein SiaP
Authors:Fischer, M, Darby, J.F, Brannigan, J.A, Turkenburg, J, Hubbard, R.E.
Deposit date:2018-07-30
Release date:2019-08-14
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Water Networks Can Determine the Affinity of Ligand Binding to Proteins.
J.Am.Chem.Soc., 141, 2019
8AY0
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BU of 8ay0 by Molmil
Crystal Structure of the peptide binding protein DppE from Bacillus subtilis in complex with murein tripeptide
Descriptor: 1,2-ETHANEDIOL, Dipeptide-binding protein DppE, L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC ACID, ...
Authors:Hughes, A.M, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-09-01
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8ARN
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BU of 8arn by Molmil
Crystal structure of the peptide binding protein, OppA, from Bacillus subtilis in complex with an endogenous tetrapeptide
Descriptor: Endogenous tetrapeptide (SER-ASN-SER-SER), Oligopeptide-binding protein OppA
Authors:Hughes, A, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-08-17
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8ARE
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BU of 8are by Molmil
Crystal structure of the peptide binding protein, OppA, from Bacillus subtilis in complex with a PhrE-derived pentapeptide
Descriptor: Oligopeptide-binding protein OppA, Phosphatase RapE inhibitor, SULFATE ION
Authors:Hughes, A, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-08-16
Release date:2023-02-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8AZB
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BU of 8azb by Molmil
Crystal Structure of the peptide binding protein DppE from Bacillus subtilis in the unliganded state
Descriptor: Dipeptide-binding protein DppE
Authors:Hughes, A.M, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-09-05
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
2V4C
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BU of 2v4c by Molmil
Structure of sialic acid binding protein (SiaP) in the presence of KDN
Descriptor: SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, deamino-beta-neuraminic acid
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2008-09-18
Release date:2010-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2WYK
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BU of 2wyk by Molmil
SiaP in complex with Neu5Gc
Descriptor: N-glycolyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, THIOCYANATE ION
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-16
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2XWK
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BU of 2xwk by Molmil
SiaP R147A mutant in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XWI
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BU of 2xwi by Molmil
SiaP R147K mutant in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2WX9
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BU of 2wx9 by Molmil
Crystal structure of the sialic acid binding periplasmic protein SiaP
Descriptor: N-glycolyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-05
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2WYP
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BU of 2wyp by Molmil
Crystal structure of sialic acid binding protein
Descriptor: SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, deamino-beta-neuraminic acid
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-18
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2XWV
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BU of 2xwv by Molmil
SiaP complex
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-05
Release date:2011-11-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XXK
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BU of 2xxk by Molmil
SiaP complex
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-10
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Siap Complex
To be Published
2XWO
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BU of 2xwo by Molmil
SiaP R147E mutant in complex with sialylamide
Descriptor: (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxamide, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XA5
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BU of 2xa5 by Molmil
Structure of substrate binding protein SiaP (A11N) in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-03-26
Release date:2011-04-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
6RB7
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BU of 6rb7 by Molmil
Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICINE, DI(HYDROXYETHYL)ETHER, ...
Authors:Owen, C.D, Bell, A, Juge, N, Walsh, M.A.
Deposit date:2019-04-09
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
Nat Microbiol, 4, 2019
6RAB
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BU of 6rab by Molmil
Ruminococcus gnavus sialic acid aldolase Wild Type
Descriptor: Putative N-acetylneuraminate lyase
Authors:Owen, C.D, Bell, A, Juge, N, Walsh, M.A.
Deposit date:2019-04-05
Release date:2019-09-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
Nat Microbiol, 4, 2019
6RD1
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BU of 6rd1 by Molmil
Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant in complex with sialic acid
Descriptor: 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, Putative N-acetylneuraminate lyase
Authors:Owen, C.D, Bell, A, Juge, N, Walsh, M.A.
Deposit date:2019-04-12
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
Nat Microbiol, 4, 2019
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