2XWK

SiaP R147A mutant in complex with Neu5Ac

Summary for 2XWK

Entry DOI	10.2210/pdb2xwk/pdb
Related	2CEX 2CEY 2V4C 2WX9 2WYK 2WYP 2XA5 2XWI 2XWO 2XWV 2XXK
Descriptor	SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, N-acetyl-beta-neuraminic acid (3 entities in total)
Functional Keywords	transport protein, periplasmic binding protein, trap transporter, sugar transport
Biological source	HAEMOPHILUS INFLUENZAE
Total number of polymer chains	1
Total formula weight	35255.77
Authors	Fischer, M.,Hubbard, R.E. (deposition date: 2010-11-04, release date: 2011-11-23, Last modification date: 2023-12-20)
Primary citation	Fischer, M.,Hopkins, A.P.,Severi, E.,Hawkhead, J.,Bawdon, D.,Watts, A.G.,Hubbard, R.E.,Thomas, G.H. Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding. J.Biol.Chem., 290:27113-, 2015 Cited by PubMed: 26342690 DOI: 10.1074/JBC.M115.656603 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation