5W2L
 
 | | Structure of a central domain of human Ctc1 | | Descriptor: | CST complex subunit CTC1, MERCURY (II) ION | | Authors: | Rice, C, Skordalakes, E. | | Deposit date: | 2017-06-06 | | Release date: | 2017-11-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.
Nucleic Acids Res., 46, 2018
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5UN7
 | | Structure of the human POT1-TPP1 telomeric complex | | Descriptor: | Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ... | | Authors: | Rice, C, Doukov, T, Skordalakes, E. | | Deposit date: | 2017-01-30 | | Release date: | 2017-04-12 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun, 8, 2017
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7S1O
 | | Structure of human POT1C | | Descriptor: | Protection of telomeres protein 1, ZINC ION | | Authors: | Aramburu, T, Skordalakes, E. | | Deposit date: | 2021-09-02 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
Comput Struct Biotechnol J, 20, 2022
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7S1T
 | | Structure of the human POT1-TPP1 complex | | Descriptor: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | | Authors: | Aramburu, T, Skordalakes, E. | | Deposit date: | 2021-09-02 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
Comput Struct Biotechnol J, 20, 2022
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7S1U
 | | Structure of human POT1C | | Descriptor: | Protection of telomeres protein 1, ZINC ION | | Authors: | Aramburu, T, Skordalakes, E. | | Deposit date: | 2021-09-02 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
Comput Struct Biotechnol J, 20, 2022
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4JQF
 | | Structure of the C-terminal domain of human telomeric Stn1 | | Descriptor: | CST complex subunit STN1 | | Authors: | Bryan, C.F, Rice, C.T, Harkisheimer, M, Schultz, D, Skordalakes, E. | | Deposit date: | 2013-03-20 | | Release date: | 2013-06-05 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
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4JOI
 | | Crystal structure of the human telomeric Stn1-Ten1 complex | | Descriptor: | CST complex subunit STN1, CST complex subunit TEN1 | | Authors: | Bryan, C, Rice, C, Harkisheimer, M, Schultz, D, Skordalakes, E. | | Deposit date: | 2013-03-18 | | Release date: | 2013-05-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
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1ROC
 | | Crystal structure of the histone deposition protein Asf1 | | Descriptor: | Anti-silencing protein 1, BROMIDE ION | | Authors: | Daganzo, S.M, Erzberger, J.P, Lam, W.M, Skordalakes, E, Zhang, R, Franco, A.A, Brill, S.J, Adams, P.D, Berger, J.M, Kaufman, P.D. | | Deposit date: | 2003-12-02 | | Release date: | 2003-12-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure and function of the conserved core of histone deposition protein Asf1.
Curr.Biol., 13, 2003
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1AIX
 | | HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROVAL | | Descriptor: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ... | | Authors: | Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J. | | Deposit date: | 1997-04-30 | | Release date: | 1997-10-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Protein Sci., 1, 1992
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1AI8
 | | HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG | | Descriptor: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIB, ... | | Authors: | Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J. | | Deposit date: | 1997-05-01 | | Release date: | 1997-10-15 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Protein Sci., 1, 1992
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1ZMR
 | | Crystal Structure of the E. coli Phosphoglycerate Kinase | | Descriptor: | CALCIUM ION, Phosphoglycerate kinase | | Authors: | Marqusee, S. | | Deposit date: | 2005-05-10 | | Release date: | 2006-05-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability.
J.Mol.Biol., 368, 2007
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