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1LI7
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BU of 1li7 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase with Cysteine Substrate Bound
Descriptor: CYSTEINE, CYSTEINYL-TRNA SYNTHETASE, ZINC ION
Authors:Newberry, K.J, Hou, Y.-M, Perona, J.J.
Deposit date:2002-04-17
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1ZJW
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BU of 1zjw by Molmil
Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ...
Authors:Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J.
Deposit date:2005-05-01
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase.
J.Biol.Chem., 280, 2005
1KC6
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BU of 1kc6 by Molmil
HincII Bound to Cognate DNA
Descriptor: 5'-D(P*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, TYPE II RESTRICTION ENZYME HINCII
Authors:Horton, N.C, Dorner, L.F, Perona, J.J.
Deposit date:2001-11-07
Release date:2001-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation.
Nat.Struct.Biol., 9, 2002
2I9K
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BU of 2i9k by Molmil
Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI
Descriptor: 5'-D(*T*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3', Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Youngblood, B, Shieh, F.K, De Los Rios, S, Perona, J.J, Reich, N.O.
Deposit date:2006-09-05
Release date:2006-10-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI
J.Mol.Biol., 362, 2006
2GQQ
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BU of 2gqq by Molmil
Crystal Structure of E. coli Leucine-responsive regulatory protein (Lrp)
Descriptor: Leucine-responsive regulatory protein
Authors:de los Rios, S, Perona, J.J.
Deposit date:2006-04-21
Release date:2007-03-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the Escherichia coli Leucine-responsive Regulatory Protein Lrp Reveals a Novel Octameric Assembly.
J.Mol.Biol., 366, 2007
1GTR
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BU of 1gtr by Molmil
STRUCTURAL BASIS OF ANTICODON LOOP RECOGNITION BY GLUTAMINYL-TRNA SYNTHETASE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLUTAMINYL-tRNA SYNTHETASE, RNA (74-MER)
Authors:Rould, M.A, Perona, J.J, Steitz, T.A.
Deposit date:1993-09-15
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase.
Nature, 352, 1991
1EUY
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BU of 1euy by Molmil
GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA MUTANT AND AN ACTIVE SITE INHIBITOR
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
Authors:Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
Deposit date:2000-04-19
Release date:2000-06-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
1EOP
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BU of 1eop by Molmil
ECORV BOUND TO COGNATE DNA
Descriptor: DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV
Authors:Horton, N.C, Perona, J.J.
Deposit date:2000-03-23
Release date:2000-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic snapshots along a protein-induced DNA-bending pathway.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EUQ
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BU of 1euq by Molmil
CRYSTAL STRUCTURE OF GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA-GLN MUTANT AND AN ACTIVE-SITE INHIBITOR
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
Authors:Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
Deposit date:2000-04-17
Release date:2000-06-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
1U0B
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BU of 1u0b by Molmil
Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys
Descriptor: Cysteine--tRNA ligase, ZINC ION, cysteinyl tRNA
Authors:Hauenstein, S, Zhang, C.M, Hou, Y.M, Perona, J.J.
Deposit date:2004-07-13
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Shape-selective RNA recognition by cysteinyl-tRNA synthetase
Nat.Struct.Mol.Biol., 11, 2004
1STX
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BU of 1stx by Molmil
Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+
Descriptor: 5'-D(*AP*AP*AP*GP*AP*T)-3', 5'-D(P*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, ...
Authors:Horton, N.C, Perona, J.J.
Deposit date:2004-03-25
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites
Biochemistry, 43, 2004
1RV5
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BU of 1rv5 by Molmil
COMPLEX OF ECORV ENDONUCLEASE WITH D(AAAGAT)/D(ATCTT)
Descriptor: 5'-D(*AP*AP*AP*GP*AP*T*AP*TP*CP*TP*T)-3', ECORV ENDONUCLEASE
Authors:Horton, N.C, Perona, J.J.
Deposit date:1998-06-01
Release date:1998-11-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d(AAAGAT) + d(ATCTT).
J.Mol.Biol., 277, 1998
1SX8
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BU of 1sx8 by Molmil
EcoRV bound to cognate DNA and Mn2+
Descriptor: 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, Type II restriction enzyme EcoRV
Authors:Horton, N.C, Perona, J.J.
Deposit date:2004-03-30
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites
Biochemistry, 43, 2004
1SUZ
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BU of 1suz by Molmil
The structure of K92A EcoRV bound to cognate DNA and Mg2+
Descriptor: 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MAGNESIUM ION, SODIUM ION, ...
Authors:Horton, N.C, Perona, J.J.
Deposit date:2004-03-26
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites.
Biochemistry, 43, 2004
1SX5
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BU of 1sx5 by Molmil
K38A EcoRV bound to cleaved DNA and Mn2+: P1 crystal form
Descriptor: 5'-D(*AP*AP*AP*GP*AP*T)-3', 5'-D(P*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, ...
Authors:Horton, N.C, Perona, J.J.
Deposit date:2004-03-30
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:DNA cleavage by EcoRV endonuclease: Two metal ions in three metal ion binding sites
Biochemistry, 43, 2004
1TX3
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BU of 1tx3 by Molmil
HINCII BOUND TO COGNATE DNA
Descriptor: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HindII
Authors:Horton, N.C, Dorner, L.F, Perona, J.J.
Deposit date:2004-07-01
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Biochemistry, 43, 2004
1EXD
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BU of 1exd by Molmil
CRYSTAL STRUCTURE OF A TIGHT-BINDING GLUTAMINE TRNA BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE TRNA APTAMER, GLUTAMINYL-TRNA SYNTHETASE, ...
Authors:Bullock, T.L, Sherlin, L.D, Perona, J.J.
Deposit date:2000-05-02
Release date:2000-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Tertiary core rearrangements in a tight binding transfer RNA aptamer.
Nat.Struct.Biol., 7, 2000
1AZ4
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BU of 1az4 by Molmil
ECORV ENDONUCLEASE, UNLIGANDED, FORM B, T93A MUTANT
Descriptor: ECORV ENDONUCLEASE
Authors:Perona, J, Martin, A.
Deposit date:1997-11-24
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1AZ3
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BU of 1az3 by Molmil
ECORV ENDONUCLEASE, UNLIGANDED, FORM B
Descriptor: ECORV ENDONUCLEASE
Authors:Perona, J, Martin, A.
Deposit date:1997-11-24
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1QRS
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BU of 1qrs by Molmil
GLUTAMINYL-TRNA SYNTHETASE MUTANT D235N COMPLEXED WITH GLUTAMINE TRANSFER RNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN2
Authors:Arnez, J.G, Steitz, T.A.
Deposit date:1996-06-14
Release date:1996-12-07
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP.
Biochemistry, 35, 1996
1QRT
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BU of 1qrt by Molmil
GLUTAMINYL-TRNA SYNTHETASE MUTANT D235G COMPLEXED WITH GLUTAMINE TRANSFER RNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN2
Authors:Arnez, J.G, Steitz, T.A.
Deposit date:1996-06-14
Release date:1996-12-07
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP.
Biochemistry, 35, 1996
1QRU
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BU of 1qru by Molmil
GLUTAMINYL-TRNA SYNTHETASE MUTANT I129T COMPLEXED WITH GLUTAMINE TRANSFER RNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN2
Authors:Arnez, J.G, Steitz, T.A.
Deposit date:1996-06-14
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP.
Biochemistry, 35, 1996
1NYL
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BU of 1nyl by Molmil
Unliganded glutaminyl-tRNA synthetase
Descriptor: Glutaminyl-tRNA synthetase
Authors:Sherlin, L.D, Perona, J.P.
Deposit date:2003-02-12
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:tRNA-Dependent Active Site Assembly in a Class I Aminoacyl-tRNA Synthetase.
Structure, 11, 2003
1BGB
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BU of 1bgb by Molmil
ECORV ENDONUCLEASE COMPLEX WITH 5'-CGGGATATCCC DNA
Descriptor: DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), ECORV ENDONUCLEASE
Authors:Perona, J, Horton, N.C.
Deposit date:1998-05-28
Release date:1998-10-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts.
J.Biol.Chem., 273, 1998
3TL4
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BU of 3tl4 by Molmil
Crystal Structure of the tRNA Binding Domain of Glutaminyl-tRNA Synthetase from Saccharomyces cerevisiae
Descriptor: Glutaminyl-tRNA synthetase
Authors:Grant, T.D, Snell, E.H.
Deposit date:2011-08-29
Release date:2011-11-30
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase.
Nucleic Acids Res., 40, 2012

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