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8Q0P
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BU of 8q0p by Molmil
Crystal Structure of an N-terminal Domain of Variant Surface Glycoprotein 21 (VSG21) of Trypanosome brucei brucei Lister 427
Descriptor: Variant surface glycoprotein MITat 1.21
Authors:Zeelen, J.P, Stebbins, C.E.
Deposit date:2023-07-28
Release date:2023-09-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8Q0E
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BU of 8q0e by Molmil
Crystal Structure of the N-terminal Domain of Variant Surface Glycoprotein 545 (VSG545) of Trypanosome brucei brucei Lister 427
Descriptor: Variant surface glycoprotein 545
Authors:van Straaten, M, Stebbins, C.E.
Deposit date:2023-07-28
Release date:2023-09-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
6Z7E
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BU of 6z7e by Molmil
Variant Surface Glycoprotein VSGsur mutant H122A soaked in 7.7 mM suramin
Descriptor: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E.
Deposit date:2020-05-30
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.663 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7C
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BU of 6z7c by Molmil
Variant Surface Glycoprotein VSGsur mutant H122A
Descriptor: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E.
Deposit date:2020-05-30
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z8G
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BU of 6z8g by Molmil
Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure.
Descriptor: BROMIDE ION, SULFATE ION, Variant surface glycoprotein MITat 1.13, ...
Authors:Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J.
Deposit date:2020-06-02
Release date:2021-03-17
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7B
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BU of 6z7b by Molmil
Variant Surface Glycoprotein VSGsur bound to suramin
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E, Jeffrey, P.
Deposit date:2020-05-30
Release date:2021-03-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7D
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BU of 6z7d by Molmil
Variant Surface Glycoprotein VSGsur mutant H122A soaked in 0.77 mM Suramin.
Descriptor: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E.
Deposit date:2020-05-30
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z79
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BU of 6z79 by Molmil
Variant Surface Glycoprotein VSGsur, I3C ("Magic Triangle") derivative used for phasing of the structure and subsequently as a model for molecular replacement of native, mutants, and drug soaks.
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E.
Deposit date:2020-05-30
Release date:2021-03-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z8H
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BU of 6z8h by Molmil
Crystal structure of Variant Surface Glycoprotein VSG13
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variant surface glycoprotein MITat 1.13, ...
Authors:Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J.
Deposit date:2020-06-02
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7A
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BU of 6z7a by Molmil
Variant Surface Glycoprotein VSGsur
Descriptor: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zeelen, J.P, Straaten van, M, Stebbins, C.E, Hashemi, H.
Deposit date:2020-05-30
Release date:2021-05-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:A Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Nat Microbiol, 6, 2021
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PDB entries from 2024-10-09

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