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7OG1
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BU of 7og1 by Molmil
AP2 clathrin adaptor core in complex with cargo peptide and FCHO2
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OI5
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BU of 7oi5 by Molmil
Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved)
Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OIQ
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BU of 7oiq by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OFP
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BU of 7ofp by Molmil
Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor
Descriptor: AP-2 complex subunit mu, CITRIC ACID, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHO
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BU of 7oho by Molmil
Crystal structure of AP2 FCHO2 chimera
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7Z5C
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BU of 7z5c by Molmil
Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R.
Deposit date:2022-03-09
Release date:2022-05-11
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
8QQF
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BU of 8qqf by Molmil
TBC1D23 PH domain complexed with STX16 TLY motif
Descriptor: GLYCEROL, PHOSPHATE ION, Syntaxin-16, ...
Authors:Kaufman, J.G, Owen, D.J.
Deposit date:2023-10-04
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23.
Sci Adv, 10, 2024
1UTC
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BU of 1utc by Molmil
Clathrin terminal domain complexed with TLPWDLWTT
Descriptor: AMPHIPHYSIN, CLATHRIN HEAVY CHAIN
Authors:Miele, A.E, Evans, P.R, Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
5FJZ
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BU of 5fjz by Molmil
Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWxV peptide
Descriptor: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-14
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJX
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BU of 5fjx by Molmil
Yeast delta-COP-I mu-homology domain complexed with Gcs1 WxxF peptide
Descriptor: ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN GCS1, COATOMER SUBUNIT DELTA
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-13
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FK0
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BU of 5fk0 by Molmil
Yeast delta-COP-I mu-homology domain
Descriptor: CALCIUM ION, COATOMER SUBUNIT DELTA
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-14
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJW
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BU of 5fjw by Molmil
Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWx(MSE) peptide
Descriptor: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-13
Release date:2015-11-11
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5JP2
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BU of 5jp2 by Molmil
Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
Descriptor: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J, Wrobel, A, Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
1Z2X
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BU of 1z2x by Molmil
Crystal structure of mouse Vps29
Descriptor: Vacuolar protein sorting 29
Authors:Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
1Z2W
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BU of 1z2w by Molmil
Crystal structure of mouse Vps29 complexed with Mn2+
Descriptor: GLYCEROL, MANGANESE (II) ION, Vacuolar protein sorting 29
Authors:Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
6H7W
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BU of 6h7w by Molmil
Model of retromer-Vps5 complex assembled on membrane.
Descriptor: Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ...
Authors:Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
3ZYL
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BU of 3zyl by Molmil
Structure of a truncated CALM (PICALM) ANTH domain
Descriptor: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYM
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BU of 3zym by Molmil
Structure of CALM (PICALM) in complex with VAMP8
Descriptor: GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ...
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYK
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BU of 3zyk by Molmil
Structure of CALM (PICALM) ANTH domain
Descriptor: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
Authors:Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
Deposit date:2011-08-23
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
4AFI
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BU of 4afi by Molmil
Complex between Vamp7 longin domain and fragment of delta-adaptin from AP3
Descriptor: AP-3 COMPLEX SUBUNIT DELTA-1, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7, PRASEODYMIUM ION
Authors:Kent, H.M, Evans, P.R, Luzio, J.P, Peden, A.A, Owen, D.J.
Deposit date:2012-01-19
Release date:2012-05-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of the Intracellular Sorting of the Snare Vamp7 by the Ap3 Adaptor Complex
Dev.Cell, 22, 2012
1GYW
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BU of 1gyw by Molmil
Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, CHLORIDE ION
Authors:Evans, P.R, Miele, A.E, Owen, D.J, McMahon, H.M, Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002
1GYV
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BU of 1gyv by Molmil
Gamma-adaptin appendage domain from clathrin adaptor AP1, L762E mutant
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT
Authors:Evans, P.R, Owen, D.J, McMahon, H.M, Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002
1GYU
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BU of 1gyu by Molmil
Gamma-adaptin appendage domain from clathrin adaptor AP1
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT
Authors:Evans, P.R, Owen, D.J, McMahon, H.M, Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Gamma-Adaptin Appendage Domain. Structure and Binding Site for Eps15 and Gamma-Synergin
Structure, 10, 2002
2YNO
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BU of 2yno by Molmil
yeast betaprime COP 1-304H6
Descriptor: COATOMER SUBUNIT BETA', POLY ALA
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012
2YNP
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BU of 2ynp by Molmil
yeast betaprime COP 1-604 with KTKTN motif
Descriptor: COATOMER SUBUNIT BETA', KTKTN MOTIF
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.962 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012

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