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7VAS
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BU of 7vas by Molmil
V1EG domain of V/A-ATPase from Thermus thermophilus at low ATP concentration, state1-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7VAV
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BU of 7vav by Molmil
V1EG of V/A-ATPase from Thermus thermophilus at low ATP concentration, state3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7VAU
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BU of 7vau by Molmil
V1EG of V/A-ATPase from Thermus thermophilus at low ATP concentration, state2-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7VAY
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BU of 7vay by Molmil
V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7XKH
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BU of 7xkh by Molmil
Nucleotide-depleted F1 domain of FoF1-ATPase from Bacillus PS3, state1
Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ...
Authors:Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-04-19
Release date:2022-09-21
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase.
Pnas Nexus, 1, 2022
7XKO
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BU of 7xko by Molmil
F1 domain of epsilon C-terminal domain deleted FoF1 from Bacillus PS3,state1,nucleotide depeleted
Descriptor: ATP synthase gamma chain, ATP synthase subunit alpha, ATP synthase subunit beta, ...
Authors:Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-04-20
Release date:2022-09-21
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase.
Pnas Nexus, 1, 2022
7XKQ
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BU of 7xkq by Molmil
F1 domain of FoF1-ATPase with the down form of epsilon subunit from Bacillus PS3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
Authors:Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-04-20
Release date:2022-09-21
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase.
Pnas Nexus, 1, 2022
7XKR
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BU of 7xkr by Molmil
F1 domain of FoF1-ATPase with the up form of epsilon subunit from Bacillus PS3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
Authors:Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-04-20
Release date:2022-09-21
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase.
Pnas Nexus, 1, 2022
7XKP
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BU of 7xkp by Molmil
F1 domain of epsilon C-terminal domain deleted FoF1 from Bacillus PS3,state1,unisite condition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma chain, ATP synthase subunit alpha, ...
Authors:Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-04-20
Release date:2022-09-21
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase.
Pnas Nexus, 1, 2022
6CKX
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BU of 6ckx by Molmil
Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide
Descriptor: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ...
Authors:Klein, M.G.
Deposit date:2018-03-01
Release date:2018-08-29
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J. Med. Chem., 61, 2018
8HH8
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BU of 8hh8 by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3,post-hyd,lowATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
8HH6
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BU of 8hh6 by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3,step waiting,highATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
8HH7
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BU of 8hh7 by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3, 81 degrees, lowATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
8HH5
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BU of 8hh5 by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3,120 degrees,highATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
5URM
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BU of 5urm by Molmil
Crystal structure of human BRR2 in complex with T-1206548
Descriptor: 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Klein, M.G, Tjhen, R, Qin, L.
Deposit date:2017-02-11
Release date:2017-07-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
5URJ
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BU of 5urj by Molmil
Crystal structure of human BRR2 in complex with T-3905516
Descriptor: 6-benzyl-3-[(2R)-2-(3-fluoropyridin-2-yl)-6-methyl-3,4-dihydro-2H-1-benzopyran-7-yl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(3H,8H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Klein, M.G, Tjhen, R, Qin, L.
Deposit date:2017-02-10
Release date:2017-07-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
5URK
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BU of 5urk by Molmil
Crystal structure of human BRR2 in complex with T-3935799
Descriptor: 6-benzyl-3-[3-(benzyloxy)phenyl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Qin, L, Tjhen, R, Klein, M.G.
Deposit date:2017-02-10
Release date:2017-07-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
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