3VS9
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![BU of 3vs9 by Molmil](/molmil-images/mine/3vs9) | Crystal structure of type III PKS ArsC mutant | Descriptor: | SODIUM ION, TETRAETHYLENE GLYCOL, Type III polyketide synthase | Authors: | Satou, R, Miyanaga, A, Ozawa, H, Funa, N, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | Deposit date: | 2012-04-23 | Release date: | 2013-04-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity J.Biol.Chem., 288, 2013
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3VS8
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![BU of 3vs8 by Molmil](/molmil-images/mine/3vs8) | Crystal structure of type III PKS ArsC | Descriptor: | SODIUM ION, Type III polyketide synthase | Authors: | Satou, R, Miyanaga, A, Ozawa, H, Funa, N, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | Deposit date: | 2012-04-23 | Release date: | 2013-04-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity J.Biol.Chem., 288, 2013
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3VVU
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![BU of 3vvu by Molmil](/molmil-images/mine/3vvu) | Crystal structure of reconstructed bacterial ancestral NDK, Bac1 | Descriptor: | Nucleoside diphosphate kinase | Authors: | Nemoto, N, Miyazono, K, Kimura, M, Yokobori, S, Akanuma, S, Tanokura, M, Yamagishi, A. | Deposit date: | 2012-07-27 | Release date: | 2013-06-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Experimental evidence for the thermophilicity of ancestral life Proc.Natl.Acad.Sci.USA, 110, 2013
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3VVT
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![BU of 3vvt by Molmil](/molmil-images/mine/3vvt) | Crystal structure of reconstructed archaeal ancestral NDK, Arc1 | Descriptor: | Nucleoside diphosphate kinase | Authors: | Nemoto, N, Miyazono, K, Kimura, M, Yokobori, S, Akanuma, S, Tanokura, M, Yamagishi, A. | Deposit date: | 2012-07-27 | Release date: | 2013-06-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Experimental evidence for the thermophilicity of ancestral life Proc.Natl.Acad.Sci.USA, 110, 2013
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2EJX
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![BU of 2ejx by Molmil](/molmil-images/mine/2ejx) | Crystal structure of the hypothetical protein STK_08120 from Sulfolobus tokodaii | Descriptor: | STK_08120 | Authors: | Miyakawa, T, Miyazono, K, Sawano, Y, Hatano, K, Nagata, K, Tanokura, M. | Deposit date: | 2007-03-21 | Release date: | 2008-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | A thermoacidophile-specific protein family, DUF3211, functions as a fatty acid carrier with novel binding mode J.Bacteriol., 195, 2013
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3W6V
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![BU of 3w6v by Molmil](/molmil-images/mine/3w6v) | Crystal structure of the DNA-binding domain of AdpA, the global transcriptional factor, in complex with a target DNA | Descriptor: | AdpA, DNA (5'-D(*AP*GP*GP*TP*TP*GP*GP*CP*GP*GP*GP*TP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*TP*GP*TP*GP*AP*AP*CP*CP*CP*GP*CP*CP*AP*AP*C)-3') | Authors: | Yao, M.D, Ohtsuka, J, Nagata, K, Miyazono, K, Ohnishi, Y, Tanokura, M. | Deposit date: | 2013-02-22 | Release date: | 2013-09-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Complex Structure of the DNA-binding Domain of AdpA, the Global Transcription Factor in Streptomyces griseus, and a Target Duplex DNA Reveals the Structural Basis of Its Tolerant DNA Sequence Specificity J.Biol.Chem., 288, 2013
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3W9K
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![BU of 3w9k by Molmil](/molmil-images/mine/3w9k) | Crystal structure of thermoacidophile-specific protein STK_08120 complexed with myristic acid | Descriptor: | FATTY ACID-BINDING PROTEIN, MYRISTIC ACID | Authors: | Miyakawa, T, Sawano, Y, Miyazono, K, Miyauchi, Y, Hatano, K, Tanokura, M. | Deposit date: | 2013-04-05 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A thermoacidophile-specific protein family, DUF3211, functions as a fatty acid carrier with novel binding mode. J.Bacteriol., 195, 2013
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3OV2
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![BU of 3ov2 by Molmil](/molmil-images/mine/3ov2) | Curcumin synthase 1 from Curcuma longa | Descriptor: | 1,2-ETHANEDIOL, Curcumin synthase, MALONATE ION | Authors: | Katsuyama, Y, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | Deposit date: | 2010-09-15 | Release date: | 2010-12-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | A hydrophobic cavity discovered in a curcumin synthase facilitates utilization of a beta-keto acid as an extender substrate for the atypical type III polyleteide synthase To be Published
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3OV3
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![BU of 3ov3 by Molmil](/molmil-images/mine/3ov3) | G211F mutant of curcumin synthase 1 from Curcuma longa | Descriptor: | Curcumin synthase, MALONATE ION | Authors: | Katsuyama, Y, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | Deposit date: | 2010-09-15 | Release date: | 2010-12-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A hydrophobic cavity discovered in a curcumin synthase facilitates utilization of a beta-keto acid as an extender substrate for the atypical type III polyleteide synthase To be Published
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3AI1
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![BU of 3ai1 by Molmil](/molmil-images/mine/3ai1) | The crystal structure of L-sorbose reductase from Gluconobacter frateurii complexed with NADPH and L-sorbose reveals the structure bases of its catalytic mechanism and high substrate selectivity | Descriptor: | NADPH-sorbose reductase | Authors: | Kubota, K, Nagata, K, Okai, M, Miyazono, K, Tanokura, M. | Deposit date: | 2010-05-06 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose J.Mol.Biol., 407, 2011
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3AI3
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![BU of 3ai3 by Molmil](/molmil-images/mine/3ai3) | The crystal structure of L-Sorbose reductase from Gluconobacter frateurii complexed with NADPH and L-sorbose | Descriptor: | L-sorbose, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-sorbose reductase, ... | Authors: | Kubota, K, Nagata, K, Okai, M, Miyazono, K, Tanokura, M. | Deposit date: | 2010-05-07 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose J.Mol.Biol., 407, 2011
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3AI2
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![BU of 3ai2 by Molmil](/molmil-images/mine/3ai2) | The crystal structure of L-sorbose reductase from Gluconobacter frateurii complexed with NADPH | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-sorbose reductase | Authors: | Kubota, K, Nagata, K, Okai, M, Miyazono, K, Tanokura, M. | Deposit date: | 2010-05-07 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose J.Mol.Biol., 407, 2011
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2Z1N
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![BU of 2z1n by Molmil](/molmil-images/mine/2z1n) | Crystal structure of APE0912 from Aeropyrum pernix K1 | Descriptor: | SODIUM ION, dehydrogenase | Authors: | Ichimura, T, Yamamura, A, Mimoto, F, Ohtsuka, J, Miyazono, K, Okai, M, Kamo, M, Lee, W.-C, Nagata, K, Tanokura, M. | Deposit date: | 2007-05-10 | Release date: | 2008-03-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique catalytic triad revealed by the crystal structure of APE0912, a short-chain dehydrogenase/reductase family protein from Aeropyrum pernix K1 Proteins, 70, 2008
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3A2E
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![BU of 3a2e by Molmil](/molmil-images/mine/3a2e) | Crystal structure of ginkbilobin-2, the novel antifungal protein from Ginkgo biloba seeds | Descriptor: | Ginkbilobin-2 | Authors: | Miyakawa, T, Miyazono, K, Sawano, Y, Hatano, K, Tanokura, M. | Deposit date: | 2009-05-13 | Release date: | 2009-06-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Crystal structure of ginkbilobin-2 with homology to the extracellular domain of plant cysteine-rich receptor-like kinases Proteins, 77, 2009
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2ZUA
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![BU of 2zua by Molmil](/molmil-images/mine/2zua) | Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata | Descriptor: | Nucleoside diphosphate kinase | Authors: | Ichimura, T, Yamamura, A, Ohtsuka, J, Miyazono, K, Okai, M, Nagata, K, Tanokura, M. | Deposit date: | 2008-10-15 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases Biophys.J., 96, 2009
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2ZTS
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![BU of 2zts by Molmil](/molmil-images/mine/2zts) | |
7WAB
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![BU of 7wab by Molmil](/molmil-images/mine/7wab) | Crystal structure of the prolyl endoprotease, PEP, from Aspergillus niger | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPASS (Complex proteins associated with Set1p) component shg1 family protein, ... | Authors: | Miyazono, K, Kubota, K, Takahashi, K, Tanokura, M. | Deposit date: | 2021-12-14 | Release date: | 2022-01-12 | Last modified: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger. Biochem.Biophys.Res.Commun., 591, 2022
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6L2N
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![BU of 6l2n by Molmil](/molmil-images/mine/6l2n) | Crystal structure of the R.PabI(Y68F-K154A)-dsDNA(GTAC-3bp-GTAC) complex | Descriptor: | DNA (5'-D(*TP*CP*AP*GP*CP*AP*GP*TP*AP*CP*TP*AP*AP*GP*TP*AP*CP*TP*GP*CP*TP*GP*A)-3'), RE_R_Pab1 domain-containing protein | Authors: | Miyazono, K, Wang, D, Ito, T, Tanokura, M. | Deposit date: | 2019-10-05 | Release date: | 2020-03-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI. Nucleic Acids Res., 48, 2020
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6L2O
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![BU of 6l2o by Molmil](/molmil-images/mine/6l2o) | Crystal structure of the R.PabI(Y68F-K154A)-dsDNA(GTAC-5bp-GTAC) complex | Descriptor: | DNA (5'-D(*CP*A*GP*CP*AP*GP*TP*AP*CP*TP*TP*AP*AP*AP*GP*TP*AP*CP*TP*GP*CP*TP*G)-3'), RE_R_Pab1 domain-containing protein | Authors: | Miyazono, K, Wang, D, Ito, T, Tanokura, M. | Deposit date: | 2019-10-05 | Release date: | 2020-03-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI. Nucleic Acids Res., 48, 2020
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6M64
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![BU of 6m64 by Molmil](/molmil-images/mine/6m64) | Crystal structure of SMAD2 in complex with CBP | Descriptor: | CBP, Mothers against decapentaplegic homolog 2 | Authors: | Miyazono, K, Ito, T, Wada, H, Tanokura, M. | Deposit date: | 2020-03-13 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling. Sci.Signal., 13, 2020
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6M3L
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![BU of 6m3l by Molmil](/molmil-images/mine/6m3l) | Crystal structure of the R.PabI(Y68F-K154A)-dsDNA(nonspecific) complex | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*TP*CP*GP*AP*TP*TP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*GP*CP*G)-3'), RE_R_Pab1 domain-containing protein | Authors: | Miyazono, K, Wang, D, Ito, T, Tanokura, M. | Deposit date: | 2020-03-04 | Release date: | 2020-03-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI. Nucleic Acids Res., 48, 2020
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7CFA
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![BU of 7cfa by Molmil](/molmil-images/mine/7cfa) | |
7CO1
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![BU of 7co1 by Molmil](/molmil-images/mine/7co1) | Crystal structure of SMAD2 in complex with wild-type CBP | Descriptor: | CREB-binding protein, Mothers against decapentaplegic homolog 2 | Authors: | Miyazono, K, Wada, H, Ito, T, Tanokura, M. | Deposit date: | 2020-08-03 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling. Sci.Signal., 13, 2020
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5ZB8
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![BU of 5zb8 by Molmil](/molmil-images/mine/5zb8) | |
5ZOJ
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![BU of 5zoj by Molmil](/molmil-images/mine/5zoj) | Crystal structure of human SMAD2-MAN1 complex | Descriptor: | Inner nuclear membrane protein Man1, Mothers against decapentaplegic homolog 2 | Authors: | Miyazono, K, Ohno, Y, Ito, T, Tanokura, M. | Deposit date: | 2018-04-13 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Structural basis for receptor-regulated SMAD recognition by MAN1 Nucleic Acids Res., 46, 2018
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