3W6V

Crystal structure of the DNA-binding domain of AdpA, the global transcriptional factor, in complex with a target DNA

Summary for 3W6V

• Entry DOI: 10.2210/pdb3w6v/pdb
• Descriptor: AdpA, DNA (5'-D(*CP*TP*GP*TP*GP*AP*AP*CP*CP*CP*GP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*AP*GP*GP*TP*TP*GP*GP*CP*GP*GP*GP*TP*TP*CP*AP*C)-3'), ... (4 entities in total)
• Functional Keywords: h-t-h motif, sequence-specific dna binding transcription factor activity, dna-binding, intracellular, transcription activator-dna complex, transcription activator/dna
• Biological source: Streptomyces griseus
• Total number of polymer chains: 3
• Total formula weight: 26542.15

Authors

Yao, M.D.,Ohtsuka, J.,Nagata, K.,Miyazono, K.,Ohnishi, Y.,Tanokura, M. (deposition date: 2013-02-22, release date: 2013-09-18, Last modification date: 2023-11-08)

• Primary citation: Yao, M.D.,Ohtsuka, J.,Nagata, K.,Miyazono, K.,Zhi, Y.,Ohnishi, Y.,Tanokura, M.; Complex Structure of the DNA-binding Domain of AdpA, the Global Transcription Factor in Streptomyces griseus, and a Target Duplex DNA Reveals the Structural Basis of Its Tolerant DNA Sequence Specificity; J.Biol.Chem., 288:31019-31029, 2013; PubMed: 24019524; DOI: 10.1074/jbc.M113.473611

Experimental method

X-RAY DIFFRACTION (2.95 Å)