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The Jak1 kinase domain in complex with compound 37
Descriptor:	(1R,2S)-2-{[8-oxo-2-(1H-pyrazol-4-yl)-5,8-dihydropyrido[3,4-d]pyrimidin-4-yl]amino}cyclopentanecarbonitrile, Tyrosine-protein kinase JAK1
Authors:	Fong, R, Lupardus, P.J.
Deposit date:	2013-04-16
Release date:	2013-10-02
Last modified:	2013-10-23
Method:	X-RAY DIFFRACTION (2.73 Å)
Cite:	Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013

JAK1 kinase (JH1 domain) in complex with compound 6
Descriptor:	4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-8(7H)-one, Tyrosine-protein kinase JAK1
Authors:	Eigenbrot, C, Shia, S.
Deposit date:	2013-04-16
Release date:	2013-10-02
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013