8DGS
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![BU of 8dgs by Molmil](/molmil-images/mine/8dgs) | Cryo-EM structure of a RAS/RAF complex (state 1) | Descriptor: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Eck, M.J, Jeon, H, Park, E, Rawson, S. | Deposit date: | 2022-06-24 | Release date: | 2023-07-05 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of a RAS/RAF recruitment complex. Nat Commun, 14, 2023
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8W69
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![BU of 8w69 by Molmil](/molmil-images/mine/8w69) | DegQ-b-casein complex | Descriptor: | Casein fragment, peptidase Do | Authors: | Lee, I.-G, Jeon, H. | Deposit date: | 2023-08-28 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of E. coli Deg-b-casein complex To Be Published
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6Q0J
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![BU of 6q0j by Molmil](/molmil-images/mine/6q0j) | Structure of a MAPK pathway complex | Descriptor: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Park, E, Rawson, S, Jeon, H, Eck, M.J. | Deposit date: | 2019-08-01 | Release date: | 2019-10-09 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
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6Q0K
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![BU of 6q0k by Molmil](/molmil-images/mine/6q0k) | Structure of a MAPK pathway complex | Descriptor: | 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf | Authors: | Park, E, Rawson, S, Jeon, H, Eck, M.J. | Deposit date: | 2019-08-01 | Release date: | 2019-10-09 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
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1NU2
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![BU of 1nu2 by Molmil](/molmil-images/mine/1nu2) | Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1, peptide derived from murine Apolipoprotein E Receptor-2 | Authors: | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | Deposit date: | 2003-01-30 | Release date: | 2003-04-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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1NTV
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![BU of 1ntv by Molmil](/molmil-images/mine/1ntv) | Crystal Structure of the Disabled-1 (Dab1) PTB domain-ApoER2 peptide complex | Descriptor: | Apolipoprotein E Receptor-2 peptide, Disabled homolog 1, PHOSPHATE ION | Authors: | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | Deposit date: | 2003-01-30 | Release date: | 2003-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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3MCD
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![BU of 3mcd by Molmil](/molmil-images/mine/3mcd) | Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor | Descriptor: | Cell division topological specificity factor | Authors: | Kang, G.B, Song, H.E, Kim, M.K, Youn, H.S, Lee, J.G, An, J.Y, Jeon, H, Chun, J.S, Eom, S.H. | Deposit date: | 2010-03-29 | Release date: | 2010-05-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor Mol.Microbiol., 76, 2010
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8KIC
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![BU of 8kic by Molmil](/molmil-images/mine/8kic) | Bacterial serine protease | Descriptor: | Lysozyme fragment (unknown sequence), peptidase Do | Authors: | Lee, I.-G, Jeon, H. | Deposit date: | 2023-08-23 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structure of bacterial serine protease To Be Published
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3QX1
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![BU of 3qx1 by Molmil](/molmil-images/mine/3qx1) | Crystal structure of FAF1 UBX domain | Descriptor: | FAS-associated factor 1, SULFATE ION | Authors: | Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E. | Deposit date: | 2011-03-01 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Dissection of the interaction between FAF1 UBX and p97 To be Published
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3QWZ
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![BU of 3qwz by Molmil](/molmil-images/mine/3qwz) | Crystal structure of FAF1 UBX-p97N-domain complex | Descriptor: | FAS-associated factor 1, Transitional endoplasmic reticulum ATPase | Authors: | Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E. | Deposit date: | 2011-02-28 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dissection of the interaction between FAF1 UBX and p97 To be Published
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1XFE
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![BU of 1xfe by Molmil](/molmil-images/mine/1xfe) | Solution structure of the LA7-EGFA pair from the LDL receptor | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor | Authors: | Beglova, N, Jeon, H, Fisher, C, Blacklow, S.C. | Deposit date: | 2004-09-14 | Release date: | 2004-11-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Cooperation between Fixed and Low pH-Inducible Interfaces Controls Lipoprotein Release by the LDL Receptor Mol.Cell, 16, 2004
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7VGX
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![BU of 7vgx by Molmil](/molmil-images/mine/7vgx) | Neuropeptide Y Y1 Receptor (NPY1R) in Complex with G Protein and its endogeneous Peptide-Agonist Neuropeptide Y (NPY) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Park, C, Kim, J, Jeong, H, Kang, H, Bang, I, Choi, H.-J. | Deposit date: | 2021-09-19 | Release date: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of neuropeptide Y signaling through Y1 receptor Nat Commun, 13, 2022
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8TKP
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![BU of 8tkp by Molmil](/molmil-images/mine/8tkp) | Structure of the C. elegans TMC-2 complex | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Clark, S, Jeong, H, Goehring, A, Posert, R, Gouaux, E. | Deposit date: | 2023-07-25 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proc.Natl.Acad.Sci.USA, 121, 2024
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8GVW
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![BU of 8gvw by Molmil](/molmil-images/mine/8gvw) | Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class2 | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | Authors: | Won, J, Jeong, H, Lee, H.H. | Deposit date: | 2022-09-16 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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8GVX
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![BU of 8gvx by Molmil](/molmil-images/mine/8gvx) | Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2 | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Won, J, Jeong, H, Lee, H.H. | Deposit date: | 2022-09-16 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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8HKP
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![BU of 8hkp by Molmil](/molmil-images/mine/8hkp) | Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry) | Descriptor: | Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-11-27 | Release date: | 2023-03-22 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7X6C
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![BU of 7x6c by Molmil](/molmil-images/mine/7x6c) | Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1 | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | Authors: | Won, J, Jeong, H, Lee, H.H. | Deposit date: | 2022-03-07 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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7X6I
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![BU of 7x6i by Molmil](/molmil-images/mine/7x6i) | Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1 | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Won, J, Jeong, H, Lee, H.H. | Deposit date: | 2022-03-07 | Release date: | 2023-04-26 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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6L3T
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![BU of 6l3t by Molmil](/molmil-images/mine/6l3t) | Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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6L3V
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![BU of 6l3v by Molmil](/molmil-images/mine/6l3v) | The R15G mutant of human Cx31.3/GJC3 connexin hemichannel | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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6L3U
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![BU of 6l3u by Molmil](/molmil-images/mine/6l3u) | Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium | Descriptor: | CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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7XNH
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![BU of 7xnh by Molmil](/molmil-images/mine/7xnh) | Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-28 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKI
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![BU of 7xki by Molmil](/molmil-images/mine/7xki) | Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562 | Authors: | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | Deposit date: | 2022-04-19 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XNV
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![BU of 7xnv by Molmil](/molmil-images/mine/7xnv) | Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-29 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKT
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![BU of 7xkt by Molmil](/molmil-images/mine/7xkt) | Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | Deposit date: | 2022-04-20 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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