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5KQ4
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BU of 5kq4 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2 and synthetic cap analog
Descriptor: Proline-rich nuclear receptor coactivator 2, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate, mRNA decapping complex subunit 2, ...
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
5KQ1
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BU of 5kq1 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2
Descriptor: Proline-rich nuclear receptor coactivator 2, mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
7T7H
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BU of 7t7h by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356
Descriptor: 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION
Authors:Peters, J.K, Gross, J.D.
Deposit date:2021-12-15
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78000259 Å)
Cite:Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9.
Acs Chem.Biol., 17, 2022
2JVB
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BU of 2jvb by Molmil
Solution Structure of Catalytic Domain of yDcp2
Descriptor: mRNA-decapping enzyme subunit 2
Authors:Deshmukh, M, Gross, J.
Deposit date:2007-09-16
Release date:2008-03-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2.
Mol.Cell, 29, 2008
6AM0
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BU of 6am0 by Molmil
Crystal structure of K. lactis Edc1-Dcp1-Dcp2-Edc3 decapping complex with synthetic cap substrate analog
Descriptor: KLLA0A01474p, KLLA0A11308p, KLLA0E01827p, ...
Authors:Mugridge, J.S, Gross, J.D.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.
Nat Commun, 9, 2018
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