5JGI
| X-ray structure of neuropilin-1 b1 domain complexed with M45 compound | Descriptor: | N-ALPHA-L-ACETYL-ARGININE, Neuropilin-1 | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-04-20 | Release date: | 2017-05-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
|
|
5L73
| MAM domain of human neuropilin-1 | Descriptor: | BICINE, CALCIUM ION, Neuropilin-1, ... | Authors: | Yelland, T, Djordjevic, S. | Deposit date: | 2016-06-01 | Release date: | 2016-10-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture. Structure, 24, 2016
|
|
5DN2
| Human NRP2 b1 domain in complex with the peptide corresponding to the C-terminus of VEGF-A | Descriptor: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Neuropilin-2, ... | Authors: | Tsai, Y.C.I, Frankel, P, Fotinou, C, Rana, R, Zachary, I, Djordjevic, S. | Deposit date: | 2015-09-09 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket. Febs J., 283, 2016
|
|
5DQ0
| Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
|
|
1LW1
| |
6FMF
| Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid | Authors: | Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. | Deposit date: | 2018-01-31 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.811 Å) | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
|
|
6FMC
| Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | Authors: | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | Deposit date: | 2018-01-30 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
|
|
6TJT
| Neuropilin2-b1 domain in a complex with the C-terminal VEGFC peptide | Descriptor: | 1,2-ETHANEDIOL, Neuropilin-2, SULFATE ION, ... | Authors: | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | Deposit date: | 2019-11-26 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | NRP2-b1 domain in a complex with the C-terminal VEGFC peptide To Be Published
|
|
6TKK
| Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide | Descriptor: | 1,2-ETHANEDIOL, ACE-ARG-PRO-GLN-PRO-ARG, Neuropilin-1 | Authors: | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | Deposit date: | 2019-11-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide To Be Published
|
|
6TDB
| Neuropilin2-b1 domain in a complex with the C-terminal VEGFB167 peptide | Descriptor: | 1,2-ETHANEDIOL, ACETYL GROUP, C-terminal VEGFB167 peptide, ... | Authors: | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | Deposit date: | 2019-11-08 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | NRP2-b1 domain in a complex with the C-terminal VEGFB167 peptide To Be Published
|
|
1EVV
| |
3ZXO
| CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | Descriptor: | ACETATE ION, GLYCEROL, REDOX SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS, ... | Authors: | Cho, H.Y, Cho, H.J, Kang, B.S. | Deposit date: | 2011-08-13 | Release date: | 2011-08-24 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Activation of ATP Binding for the Autophosphorylation of Doss, a Mycobacterium Tuberculosis Histidine Kinase Lacking an ATP-Lid Motif. J.Biol.Chem., 288, 2013
|
|
3ZXQ
| |
1CHD
| CHEB METHYLESTERASE DOMAIN | Descriptor: | CHEB METHYLESTERASE | Authors: | West, A.H, Martinez-Hackert, E, Stock, A.M. | Deposit date: | 1995-03-09 | Release date: | 1996-01-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the catalytic domain of the chemotaxis receptor methylesterase, CheB. J.Mol.Biol., 250, 1995
|
|