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6W2V
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BU of 6w2v by Molmil
Junction 23, DHR14-DHR18
Descriptor: Junction 23 DHR14-DHR18
Authors:Bick, M.J, Brunette, T.J, Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3W
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BU of 6w3w by Molmil
An enumerative algorithm for de novo design of proteins with diverse pocket structures
Descriptor: DENOVO NTF2, NITRATE ION
Authors:Bera, A.K, Basanta, B, Dimaio, F, Sankaran, B, Baker, D.
Deposit date:2020-03-09
Release date:2020-04-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
7UDK
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BU of 7udk by Molmil
Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide
Descriptor: 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDL
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BU of 7udl by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide
Descriptor: 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDN
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BU of 7udn by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 2
Descriptor: Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UR7
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BU of 7ur7 by Molmil
17_bp_sh3, a small beta-barrel de novo designed protein
Descriptor: 17_bp_sh3
Authors:Bera, A.K, Kim, D, Baker, D.
Deposit date:2022-04-21
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:De novo design of small beta barrel proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
7UHC
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BU of 7uhc by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-03-26
Release date:2022-06-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-03-26
Release date:2022-06-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7UR8
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BU of 7ur8 by Molmil
170_h_ob, a small beta-barrel de novo designed protein
Descriptor: 170_h_ob
Authors:Bera, A.K, Kim, D, Baker, D.
Deposit date:2022-04-21
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De novo design of small beta barrel proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
7UDM
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BU of 7udm by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide)
Descriptor: 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDO
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BU of 7udo by Molmil
Crystal structure of designed helical repeat protein RPB_LRP2_R4 (proteolysis fragment?), forming pseudopolymeric filaments
Descriptor: 1,2-ETHANEDIOL, Designed helical repeat protein (DHR) RPB_LRP2_R4, PHOSPHATE ION
Authors:Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDJ
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BU of 7udj by Molmil
Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide
Descriptor: 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4
Authors:Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UE2
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BU of 7ue2 by Molmil
Crystal structure of designed helical repeat protein RPB_PLP3_R6 bound to PLPx6 peptide
Descriptor: PLPx6 peptide, RPB_PLP3_R6
Authors:Chang, Y, Ekiert, D.C, Bhabha, G.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7K3H
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BU of 7k3h by Molmil
Crystal structure of deep network hallucinated protein 0217
Descriptor: Network hallucinated protein 0217
Authors:Pellock, S.J, Anishchenko, I, Chidyausiku, T.M, Bera, A.K, DiMaio, F, Baker, D.
Deposit date:2020-09-11
Release date:2021-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:De novo protein design by deep network hallucination.
Nature, 600, 2021
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