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4Y1H
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BU of 4y1h by Molmil
Crystal structure of K33 linked tri-Ubiquitin
Descriptor: 1,2-ETHANEDIOL, Ubiquitin-40S ribosomal protein S27a
Authors:Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y.
Deposit date:2015-02-07
Release date:2015-03-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.
Biochem.J., 467, 2015
4XYZ
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BU of 4xyz by Molmil
Crystal structure of K33 linked di-Ubiquitin
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, IODIDE ION, ...
Authors:Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y.
Deposit date:2015-02-03
Release date:2015-03-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.
Biochem.J., 467, 2015
3KRN
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BU of 3krn by Molmil
Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5)
Descriptor: Protein C14A4.5, confirmed by transcript evidence
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S.
Deposit date:2009-11-19
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.918 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
4IKC
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BU of 4ikc by Molmil
Crystal Structure of catalytic domain of PTPRQ
Descriptor: CHLORIDE ION, Phosphotidylinositol phosphatase PTPRQ, SULFATE ION
Authors:Yu, K.R, Ryu, S.E, Kim, S.J.
Deposit date:2012-12-26
Release date:2013-07-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates
Acta Crystallogr.,Sect.D, 69, 2013
6IJ3
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BU of 6ij3 by Molmil
Crystal structure of PETase S121D, D186H mutant from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.J.
Deposit date:2018-10-08
Release date:2019-09-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation
Acs Catalysis, 9, 2019
6IJ5
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BU of 6ij5 by Molmil
Crystal structure of PETase P181A mutant from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.J.
Deposit date:2018-10-08
Release date:2019-09-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation
Acs Catalysis, 9, 2019
6IJ4
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BU of 6ij4 by Molmil
Crystal structure of PETase S121E, D186H mutant from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.J.
Deposit date:2018-10-08
Release date:2019-09-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation
Acs Catalysis, 9, 2019
8U08
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BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8U03
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BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
Descriptor: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8TZN
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BU of 8tzn by Molmil
Crystal structure of 10E8-GT10.2 HIV-1 MPER scaffold in complex with a non-human primate W3-01 Fab
Descriptor: 10E8-GT10.2 MPER scaffold, W3-01 Fab Heavy Chain, W3-01 Fab Light Chain
Authors:Lee, C.C.D, Wilson, I.A.
Deposit date:2023-08-27
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8TZW
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BU of 8tzw by Molmil
Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
5XJH
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BU of 5xjh by Molmil
Crystal structure of PETase from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.-J.
Deposit date:2017-05-01
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation.
Nat Commun, 9, 2018
6IJ6
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BU of 6ij6 by Molmil
Crystal structure of PETase S121E, D186H, R280A mutant from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.J.
Deposit date:2018-10-08
Release date:2019-09-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation
Acs Catalysis, 9, 2019
5F20
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BU of 5f20 by Molmil
Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:Skene, R.J.
Deposit date:2015-12-01
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.
J.Med.Chem., 59, 2016
5F1Z
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BU of 5f1z by Molmil
Structure of TYK2 with inhibitor 16: 3-azanyl-5-[(2~{S})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor: 3-azanyl-5-[(2~{S})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:Skene, R.J.
Deposit date:2015-12-01
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.
J.Med.Chem., 59, 2016
5YNS
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BU of 5yns by Molmil
Crystal structure of PETase R280A mutant from Ideonella sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Joo, S, Kim, K.-J.
Deposit date:2017-10-25
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation.
Nat Commun, 9, 2018
7BYK
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BU of 7byk by Molmil
Crystal structure of the Legionella pneumophila LegK7 effector kinase
Descriptor: LegK7
Authors:Park, S.C, Kim, T.H, Yoon, S.I.
Deposit date:2020-04-23
Release date:2020-12-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Activation of the Legionella pneumophila LegK7 Effector Kinase by the Host MOB1 Protein.
J.Mol.Biol., 433, 2020
7JU2
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BU of 7ju2 by Molmil
Crystal structure of the monomeric ETV6 PNT domain
Descriptor: FORMIC ACID, Transcription factor ETV6
Authors:Gerak, C.A.N, Kolesnikov, M, Murphy, M.E.P, McIntosh, L.P.
Deposit date:2020-08-19
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85002184 Å)
Cite:Biophysical characterization of the ETV6 PNT domain polymerization interfaces.
J.Biol.Chem., 296, 2021
5HZ2
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BU of 5hz2 by Molmil
Crystal structure of PhaC1 from Ralstonia eutropha
Descriptor: GLYCEROL, Poly-beta-hydroxybutyrate polymerase, SULFATE ION
Authors:Kim, J, Kim, K.-J.
Deposit date:2016-02-02
Release date:2016-12-07
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Ralstonia eutropha polyhydroxyalkanoate synthase C-terminal domain and reaction mechanisms.
Biotechnol J, 12, 2017
8SX3
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BU of 8sx3 by Molmil
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Descriptor: 10E8 Fab heavy chain, 10E8 light chain, 10E8-GT10.2 immunogen, ...
Authors:Huang, J, Ozorowski, G, Ward, A.B.
Deposit date:2023-05-19
Release date:2024-05-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
5JKN
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BU of 5jkn by Molmil
Crystal structure of deubiquitinase MINDY-1
Descriptor: DI(HYDROXYETHYL)ETHER, MERCURY (II) ION, PHOSPHATE ION, ...
Authors:Abdul Rehman, S.A, Kulathu, Y.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.
Mol.Cell, 63, 2016
5JQS
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BU of 5jqs by Molmil
Crystal structure of deubiquitinase MINDY-1 in complex with Ubiquitin
Descriptor: 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, Protein FAM63A, ...
Authors:Abdul Rehman, S.A, Kulathu, Y.
Deposit date:2016-05-05
Release date:2016-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.
Mol.Cell, 63, 2016
3HKM
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BU of 3hkm by Molmil
Crystal Structure of rice(Oryza sativa) Rrp46
Descriptor: Os03g0854200 protein
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S.
Deposit date:2009-05-25
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9845 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
7NFW
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BU of 7nfw by Molmil
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide
Descriptor: 14-3-3 protein sigma, Estrogen receptor
Authors:Roversi, P, Falcicchio, M, Doveston, R.
Deposit date:2021-02-08
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Cooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification.
Chem Sci, 12, 2021
7NIZ
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BU of 7niz by Molmil
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide and ligands Fusicoccin-A and WR-1065
Descriptor: 14-3-3 protein sigma, Estrogen receptor, FUSICOCCIN, ...
Authors:Roversi, P, Falcicchio, M, Doveston, R.
Deposit date:2021-02-14
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Cooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification.
Chem Sci, 12, 2021

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