2NQI
| Calpain 1 proteolytic core inactivated by WR13(R,R), an epoxysuccinyl-type inhibitor. | Descriptor: | CALCIUM ION, Calpain-1 catalytic subunit, N~2~-[(2S)-2-{[(2R)-4-ETHOXY-2-HYDROXY-4-OXOBUTANOYL]AMINO}PENT-4-ENOYL]-L-ARGINYL-L-TRYPTOPHANAMIDE | Authors: | Cuerrier, D, Davies, P.L, Campbell, R.L, Moldoveanu, T. | Deposit date: | 2006-10-31 | Release date: | 2007-01-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries J.Biol.Chem., 282, 2007
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2NQG
| Calpain 1 proteolytic core inactivated by WR18(S,S), an epoxysuccinyl-type inhibitor. | Descriptor: | 5-AZANYLIDYNE-N-[(2S)-4-ETHOXY-2-HYDROXY-4-OXOBUTANOYL]-L-NORVALYL-L-ARGINYL-L-TRYPTOPHANAMIDE, CALCIUM ION, Calpain-1 catalytic subunit | Authors: | Cuerrier, D, Davies, P.L, Campbell, R.L, Moldoveanu, T. | Deposit date: | 2006-10-31 | Release date: | 2007-01-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries J.Biol.Chem., 282, 2007
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2R9C
| Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide | Descriptor: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | Authors: | Qian, J, Campbell, R.L, Davies, P.L. | Deposit date: | 2007-09-12 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions. J.Med.Chem., 51, 2008
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2R9F
| Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide | Descriptor: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | Authors: | Qian, J, Campbell, R.L, Davies, P.L. | Deposit date: | 2007-09-12 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions. J.Med.Chem., 51, 2008
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2IPP
| Crystal Structure of the tetragonal form of human liver cathepsin B | Descriptor: | 2-PYRIDINETHIOL, Cathepsin B | Authors: | Huber, C.P, Campbell, R.L, Hasnain, S, Hirama, T, To, R. | Deposit date: | 2006-10-12 | Release date: | 2006-12-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of the tetragonal form of human liver cathepsin B To be Published
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1I5R
| TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX | Descriptor: | GLYCEROL, O5'-[9-(3,17B-DIHYDROXY-1,3,5(10)-ESTRATRIEN-16B-YL)-NONANOYL]ADENOSINE, TYPE 1 17 BETA-HYDROXYSTEROID DEHYDROGENASE | Authors: | Qiu, W, Campbell, R.L, Boivin, P, Poirier, D, Lin, S.-X. | Deposit date: | 2001-02-28 | Release date: | 2003-03-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors:
estradiol-adenosine hybrids with high affinity FASEB J., 16, 2002
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1IGI
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1IGJ
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5K8G
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5IRB
| Structural insight into host cell surface retention of a 1.5-MDa bacterial ice-binding adhesin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Guo, S, Phippen, S, Campbell, R, Davies, P. | Deposit date: | 2016-03-12 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Sci Adv, 3, 2017
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3DF0
| Calcium-dependent complex between m-calpain and calpastatin | Descriptor: | CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ... | Authors: | Moldoveanu, T, Gehring, K, Green, D.R. | Deposit date: | 2008-06-11 | Release date: | 2008-11-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature, 456, 2008
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5IX9
| Cell surface anchoring domain | Descriptor: | Antifreeze protein | Authors: | Guo, S, Langelaan, D. | Deposit date: | 2016-03-23 | Release date: | 2017-06-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Sci Adv, 3, 2017
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5J6Y
| Crystal structure of PA14 domain of MpAFP Antifreeze protein | Descriptor: | Antifreeze protein, CALCIUM ION, alpha-D-glucopyranose, ... | Authors: | Guo, S. | Deposit date: | 2016-04-05 | Release date: | 2017-06-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Sci Adv, 3, 2017
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5JUH
| Crystal structure of C-terminal domain (RV) of MpAFP | Descriptor: | Antifreeze protein, CALCIUM ION | Authors: | Guo, S. | Deposit date: | 2016-05-10 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Sci Adv, 3, 2017
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6W78
| crystal structure of a plant ice-binding protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antifreeze polypeptide | Authors: | Wang, Y.N, Zhang, H.Q. | Deposit date: | 2020-03-18 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.311 Å) | Cite: | Carrot 'antifreeze' protein has an irregular ice-binding site that confers weak freezing point depression but strong inhibition of ice recrystallization. Biochem.J., 477, 2020
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1MAJ
| SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | Descriptor: | IGG2A-KAPPA 26-10 FV (LIGHT CHAIN) | Authors: | Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L. | Deposit date: | 1993-09-16 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of an isolated antibody VL domain. J.Mol.Biol., 236, 1994
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1MAK
| SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | Descriptor: | IGG2A-KAPPA 26-10 FV (LIGHT CHAIN) | Authors: | Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L. | Deposit date: | 1993-09-16 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of an isolated antibody VL domain. J.Mol.Biol., 236, 1994
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