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3C52
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BU of 3c52 by Molmil
Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with phosphoglycolohydroxamic acid, a competitive inhibitor
Descriptor: CALCIUM ION, Fructose-bisphosphate aldolase, PHOSPHOGLYCOLOHYDROXAMIC ACID, ...
Authors:Coincon, M, Sygusch, J.
Deposit date:2008-01-30
Release date:2008-08-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics.
Chemistry, 14, 2008
7MXJ
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BU of 7mxj by Molmil
Crystal structure of the S/T protein kinase PknG from Corynebacterium glutamicum (residues 130-433) in complex with AMP-PNP, isoform 1
Descriptor: MAGNESIUM ION, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Serine/threonine protein kinases
Authors:Lisa, M.N, Alzari, P.M.
Deposit date:2021-05-19
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG.
Mbio, 12, 2021
7MXB
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BU of 7mxb by Molmil
Crystal structure of the S/T protein kinase PknG from Corynebacterium glutamicum in complex with AMP-PNP
Descriptor: MAGNESIUM ION, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Serine/threonine protein kinases
Authors:Lisa, M.N, Alzari, P.M.
Deposit date:2021-05-18
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG.
Mbio, 12, 2021
7MXK
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BU of 7mxk by Molmil
Crystal structure of the S/T protein kinase PknG from Corynebacterium glutamicum (residues 130-433) in complex with AMP-PNP, isoform 2
Descriptor: MAGNESIUM ION, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Serine/threonine protein kinases
Authors:Lisa, M.N, Alzari, P.M.
Deposit date:2021-05-19
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG.
Mbio, 12, 2021
6I2S
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BU of 6i2s by Molmil
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (R802A) in complex with GarA, following 2-oxoglutarate soak
Descriptor: (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, CALCIUM ION, Glycogen accumulation regulator GarA, ...
Authors:Wagner, T, Bellinzoni, M, Alzari, P.M.
Deposit date:2018-11-01
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
6I2R
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BU of 6i2r by Molmil
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA
Descriptor: CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ...
Authors:Wagner, T, Bellinzoni, M, Alzari, P.M.
Deposit date:2018-11-01
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
6I2Q
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BU of 6i2q by Molmil
Crystal structure of the wild-type SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), in complex with GarA
Descriptor: CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ...
Authors:Wagner, T, Bellinzoni, M, Alzari, P.M.
Deposit date:2018-11-01
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
4Y12
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BU of 4y12 by Molmil
Crystal structure of the S/T protein kinase PknG from Mycobacterium tuberculosis in complex with AGS
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PknG, ...
Authors:Lisa, M.N, Alzari, P.M.
Deposit date:2015-02-06
Release date:2015-05-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis.
Structure, 23, 2015
4Y0X
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BU of 4y0x by Molmil
Crystal structure of the S/T protein kinase PknG from Mycobacterium tuberculosis in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase PknG, ...
Authors:Lisa, M.N, Alzari, P.M.
Deposit date:2015-02-06
Release date:2015-05-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis.
Structure, 23, 2015
4APA
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BU of 4apa by Molmil
Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318A in apo form
Descriptor: FUMARATE HYDRATASE CLASS II
Authors:Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
Deposit date:2012-03-31
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4ADL
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BU of 4adl by Molmil
Crystal structures of Rv1098c in complex with malate
Descriptor: (2S)-2-hydroxybutanedioic acid, FUMARATE HYDRATASE CLASS II
Authors:Mechaly, A.E, Haouz, A, Miras, I, Weber, P, Shepard, W, Cole, S, Alzari, P.M, Bellinzoni, M.
Deposit date:2011-12-26
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4ADM
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BU of 4adm by Molmil
Crystal structure of Rv1098c in complex with meso-tartrate
Descriptor: FUMARATE HYDRATASE CLASS II, GLYCEROL, S,R MESO-TARTARIC ACID
Authors:Mechaly, A.E, Haouz, A, Miras, I, Weber, P, Shepard, W, Cole, S, Alzari, P.M, Bellinzoni, M.
Deposit date:2011-12-27
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4APB
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BU of 4apb by Molmil
Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318C in complex with fumarate
Descriptor: CALCIUM ION, FUMARATE HYDRATASE CLASS II, FUMARIC ACID
Authors:Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
Deposit date:2012-03-31
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
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