4Y12

Crystal structure of the S/T protein kinase PknG from Mycobacterium tuberculosis in complex with AGS

Summary for 4Y12

• Entry DOI: 10.2210/pdb4y12/pdb
• Related: 4Y0X
• Descriptor: Serine/threonine-protein kinase PknG, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION, ... (5 entities in total)
• Functional Keywords: s/t protein kinase, pkng, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Cellular location: Cytoplasm: P9WI73
• Total number of polymer chains: 1
• Total formula weight: 41596.60

Authors

Lisa, M.N.,Alzari, P.M. (deposition date: 2015-02-06, release date: 2015-05-20, Last modification date: 2024-01-10)

• Primary citation: Lisa, M.N.,Gil, M.,Andre-Leroux, G.,Barilone, N.,Duran, R.,Biondi, R.M.,Alzari, P.M.; Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis.; Structure, 23:1039-1048, 2015; PubMed: 25960409; DOI: 10.1016/j.str.2015.04.001

Experimental method

X-RAY DIFFRACTION (1.9 Å)