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5ZDR
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BU of 5zdr by Molmil
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative
Descriptor: 3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ...
Authors:Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
3VVA
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BU of 3vva by Molmil
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative
Descriptor: 3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ...
Authors:Shiba, T, Kido, Y, Sakamoto, K, Inaoka, D.K, Tsuge, C, Tatsumi, R, Balogun, E.O, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Saimoto, H, Moore, A.L, Harada, S, Kita, K.
Deposit date:2012-07-17
Release date:2013-03-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
3VV9
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BU of 3vv9 by Molmil
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei
Descriptor: Alternative oxidase, mitochondrial, FE (III) ION, ...
Authors:Shiba, T, Kido, Y, Sakamoto, K, Inaoka, D.K, Tsuge, C, Tatsumi, R, Balogun, E.O, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Saimoto, H, Moore, A.L, Harada, S, Kita, K.
Deposit date:2012-07-17
Release date:2013-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
3WXK
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BU of 3wxk by Molmil
Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol
Descriptor: GLYCEROL, Glycerol kinase, HEXANE-1,6-DIOL
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Kido, Y, Tsuge, C, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Michels, P.A.M, Kita, K, Harada, S.
Deposit date:2014-08-01
Release date:2014-12-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol.Microbiol., 94, 2014
3W54
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BU of 3w54 by Molmil
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with colletochlorin B
Descriptor: 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ...
Authors:Shiba, T, Kido, Y, Sakamoto, K, Inaoka, D.K, Tsuge, C, Tatsumi, R, Takahashi, G, Balogun, E.O, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Saimoto, H, Moore, A.L, Harada, S, Kita, K.
Deposit date:2013-01-21
Release date:2013-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
3WXL
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BU of 3wxl by Molmil
Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with adp, mg2+, and glycerol
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Glycerol kinase, ...
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Kido, Y, Tsuge, C, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Michels, P.A.M, Kita, K, Harada, S.
Deposit date:2014-08-01
Release date:2014-12-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol.Microbiol., 94, 2014
3WXI
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BU of 3wxi by Molmil
Crystal structure of trypanosoma brucei gambiense glycerol kinase (ligand-free form)
Descriptor: Glycerol kinase
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Kido, Y, Tsuge, T, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Michels, P.A.M, Kita, K, Harada, S.
Deposit date:2014-08-01
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol.Microbiol., 94, 2014
3WXJ
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BU of 3wxj by Molmil
Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol 3-phosphate
Descriptor: GLYCEROL, Glycerol kinase, SN-GLYCEROL-3-PHOSPHATE
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Kido, Y, Tsuge, C, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Michels, P.A.M, Kita, K, Harada, S.
Deposit date:2014-08-01
Release date:2014-12-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol.Microbiol., 94, 2014
3AED
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BU of 3aed by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamide
Descriptor: 2-iodo-N-phenylbenzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-phenyl-benzamide
To be Published
3AEG
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BU of 3aeg by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with N-Biphenyl-3-yl-2-iodo-benzamide
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with N-Biphenyl-3-yl-2-iodo-benzamide
To be Published
3AE8
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BU of 3ae8 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-2-trifluoromethylbenzamide
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-2-trifluoromethylbenzamide
To be Published
3AE5
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BU of 3ae5 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Methyl-N-(3-isopropoxy-phenyl)-benzamide
Descriptor: 2-methyl-N-[3-(1-methylethoxy)phenyl]benzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Methyl-N-(3-isopropoxy-phenyl)-benzamide
To be Published
3AE2
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BU of 3ae2 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide
Descriptor: 2-hydroxy-N-phenylbenzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide
To be Published
3AEE
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BU of 3aee by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5
Descriptor: 3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5
To be Published
3AE3
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BU of 3ae3 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Nitro-N-phenyl-benzamide
Descriptor: 2-nitro-N-phenylbenzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Nitro-N-phenyl-benzamide
To be Published
3AEB
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BU of 3aeb by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Phenoxy-phenyl)-2-trifluoromethyl-benzamide
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Phenoxy-phenyl)-2-trifluoromethyl-benzamide
To be Published
3AEF
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BU of 3aef by Molmil
Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket
To be Published
3AE6
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BU of 3ae6 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid
Descriptor: 2-{[3-(1-methylethoxy)phenyl]carbamoyl}benzoic acid, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid
To be Published
3AE4
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BU of 3ae4 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-methyl-benzamide
Descriptor: 2-iodo-N-methylbenzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-methyl-benzamide
To be Published
3AE1
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BU of 3ae1 by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with N-Phenyl-2-(trifluoromethyl)-benzamide
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.139 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with N-Phenyl-2-(trifluoromethyl)-benzamide
to be published
3AEC
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BU of 3aec by Molmil
Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-(1-methylethyl)-benzamid
Descriptor: 2-iodo-N-(1-methylethyl)benzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K.
Deposit date:2010-02-04
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-(1-methylethyl)-benzamid
To be Published
6J9V
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BU of 6j9v by Molmil
Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with ADP.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Glycerol kinase
Authors:Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T.
Deposit date:2019-01-24
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Reaction mechanism of the reverse reaction of African human trypanosomes glycerol kinase.
To Be Published
1UK1
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BU of 1uk1 by Molmil
Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
Descriptor: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1
Authors:Kinoshita, T.
Deposit date:2003-08-14
Release date:2004-09-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase
J.Med.Chem., 47, 2004
5AZI
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BU of 5azi by Molmil
Crystal structure of glycerol kinase from Trypanosoma brucei gambiense complexed with 4NP
Descriptor: 4-NITROPHENYL PHOSPHATE, GLYCEROL, Glycerol kinase
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Tokuoka, S.M, Tokumasu, F, Sakamoto, K, Michels, P.A.M, Harada, S, Kita, K.
Deposit date:2015-10-08
Release date:2016-10-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Biochim Biophys Acta Gen Subj, 1861, 2017
5AZJ
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BU of 5azj by Molmil
Crystal structure of glycerol kinase from Trypanosoma brucei gambiense complexed with 4NP (with disulfide bridge)
Descriptor: 4-NITROPHENYL PHOSPHATE, GLYCEROL, Glycerol kinase
Authors:Balogun, E.O, Inaoka, D.K, Shiba, T, Tokuoka, S.M, Tokumasu, F, Sakamoto, K, Michels, P.A.M, Harada, S, Kita, K.
Deposit date:2015-10-08
Release date:2016-10-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Biochim Biophys Acta Gen Subj, 1861, 2017

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