3AEE

Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5

Summary for 3AEE

• Entry DOI: 10.2210/pdb3aee/pdb
• Related: 3ABV 3AE1 3AE2 3AE3 3AE4 3AE5 3AE6 3AE7 3AE8 3AE9 3AEA 3AEB 3AEC 3AED 3AEF 3AEG
• Descriptor: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, 3-[(2S,4S,5R)-5,6-DICHLORO-2,4-DIMETHYL-1-OXOHEXYL]-4-HYDROXY-5,6-DIMETHOXY-2(1H)-PYRIDINONE, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, ... (10 entities in total)
• Functional Keywords: respiratory complex ii, inhibitors, electron transport, iron, iron-sulfur, metal-binding, mitochondrion, mitochondrion inner membrane, oxidoreductase, transit peptide, transport, tricarboxylic acid cycle, heme, transmembrane, fad-binding protein, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Sus scrofa (Pig); More
• Cellular location: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side : Q0QF01 Q007T0; Mitochondrion inner membrane ; Multi-pass membrane protein : D0VWV4 A5GZW8
• Total number of polymer chains: 4
• Total formula weight: 125909.76

Authors

Harada, S.,Sasaki, T.,Shindo, M.,Kido, Y.,Inaoka, D.K.,Omori, J.,Osanai, A.,Sakamoto, K.,Mao, J.,Matsuoka, S.,Inoue, M.,Honma, T.,Tanaka, A.,Kita, K. (deposition date: 2010-02-04, release date: 2011-02-09, Last modification date: 2023-11-01)

• Primary citation: Harada, S.,Sasaki, T.,Shindo, M.,Kido, Y.,Inaoka, D.K.,Omori, J.,Osanai, A.,Sakamoto, K.,Mao, J.,Matsuoka, S.,Inoue, M.,Honma, T.,Tanaka, A.,Kita, K.; Crystal structure of porcine heart mitochondrial complex II bound with Atpenin A5; To be Published,

Experimental method

X-RAY DIFFRACTION (3.22 Å)