1XP7
 
 | | HIV-1 subtype F genomic RNA Dimerization Initiation Site | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, SODIUM ION, ... | | Authors: | Ennifar, E, Dumas, P. | | Deposit date: | 2004-10-08 | | Release date: | 2005-10-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies
J.Mol.Biol., 356, 2006
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1XPF
 | | HIV-1 subtype A genomic RNA Dimerization Initiation Site | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, SODIUM ION, ... | | Authors: | Ennifar, E, Dumas, P. | | Deposit date: | 2004-10-08 | | Release date: | 2005-10-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies
J.Mol.Biol., 356, 2006
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1XPE
 | | HIV-1 subtype B genomic RNA Dimerization Initiation Site | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*CP*GP*CP*GP*CP*AP*CP*GP*GP*CP*AP*AP*G)-3', CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Ennifar, E, Dumas, P. | | Deposit date: | 2004-10-08 | | Release date: | 2005-10-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies
J.Mol.Biol., 356, 2006
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1Y95
 | | HIV-1 Dis(Mal) Duplex Pb-Soaked | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', LEAD (II) ION, MAGNESIUM ION | | Authors: | Ennifar, E, Walter, P, Dumas, P. | | Deposit date: | 2004-12-14 | | Release date: | 2004-12-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
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1Y6T
 | | HIV-1 Dis(Mal) Duplex Co Hexamine-Soaked | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', COBALT (III) ION, SODIUM ION | | Authors: | Ennifar, E, Walter, P, Dumas, P. | | Deposit date: | 2004-12-07 | | Release date: | 2004-12-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
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1Y99
 | | HIV-1 subtype A DIS RNA duplex | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION | | Authors: | Ennifar, E, Yusupov, M, Walter, P, Marquet, R, Ehresmann, B, Ehresmann, C, Dumas, P. | | Deposit date: | 2004-12-15 | | Release date: | 2004-12-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges
Structure Fold.Des., 7, 1999
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1Y3O
 | | HIV-1 DIS RNA subtype F- Mn soaked | | Descriptor: | 5'-R(*CP*UP*(5BU)P*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MANGANESE (II) ION, SODIUM ION | | Authors: | Ennifar, E, Dumas, P. | | Deposit date: | 2004-11-26 | | Release date: | 2005-11-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies.
J.Mol.Biol., 356, 2006
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1Y6S
 | | HIV-1 DIS(Mal) duplex Ba-soaked | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', BARIUM ION | | Authors: | Ennifar, E, Walter, P, Dumas, P. | | Deposit date: | 2004-12-07 | | Release date: | 2004-12-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
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1Y3S
 | | HIV-1 DIS RNA subtype F- MPD form | | Descriptor: | 5'-R(*CP*UP*(5BU)P*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, POTASSIUM ION | | Authors: | Ennifar, E, Dumas, P. | | Deposit date: | 2004-11-26 | | Release date: | 2005-11-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies.
J.Mol.Biol., 356, 2006
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1Y73
 | | HIV-1 Dis(Mal) Duplex Pt-Soaked | | Descriptor: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, PLATINUM (IV) ION | | Authors: | Ennifar, E, Walter, P, Dumas, P. | | Deposit date: | 2004-12-08 | | Release date: | 2004-12-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
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7L3R
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3S8U
 | | Crystal structure of a 2-azido-adenine-modified RNA | | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2011-05-31 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
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3S7C
 | | Crystal structure of a 2'-azido-uridine-modified RNA | | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2011-05-26 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
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4Y27
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7QP2
 | | 1-deazaguanosine modified-RNA Sarcin Ricin Loop | | Descriptor: | GLYCEROL, RNA (27-MER) | | Authors: | Ennifar, E, Micura, R, Bereiter, R, Renard, E, Kreutz, C. | | Deposit date: | 2021-12-30 | | Release date: | 2022-07-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (0.9 Å) | | Cite: | 1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis.
J.Am.Chem.Soc., 144, 2022
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6XUS
 | | RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base, SODIUM ION | | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | | Deposit date: | 2020-01-21 | | Release date: | 2021-02-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL).
Angew.Chem.Int.Ed.Engl., 59, 2020
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6XUR
 | | RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | | Deposit date: | 2020-01-21 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL).
Angew.Chem.Int.Ed.Engl., 59, 2020
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7QSH
 | | 23S ribosomal RNA Sarcin Ricin Loop 27-nt fragment containing a Xanthosine residue at position 2648 | | Descriptor: | 23S ribosomal RNA Sarcin Ricin Loop 27-nucleotide fragment, 9-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[[tris(oxidanyl)-$l^{5}-phosphanyl]oxymethyl]oxolan-2-yl]-2-oxidanyl-1~{H}-purin-6-one, GLYCEROL, ... | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2022-01-13 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (0.86 Å) | | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.
Nucleic Acids Res., 50, 2022
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7QUA
 | | Duplex RNA containing Xanthosine-Cytosine base pairs | | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*GP*CP*GP*(XAN)P*AP*UP*UP*AP*GP*CP*G)-3'), SODIUM ION | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2022-01-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.
Nucleic Acids Res., 50, 2022
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7QTN
 | | Duplex RNA containing Xanthosine-Cytosine base pairs | | Descriptor: | RNA (5'-R(*GP*GP*UP*AP*(RY)P*UP*GP*CP*GP*(XAN)P*UP*AP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*AP*CP*UP*GP*CP*GP*(XAM)P*UP*AP*CP*C)-3') | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2022-01-14 | | Release date: | 2023-01-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.
Nucleic Acids Res., 50, 2022
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5MRX
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6ZXZ
 | | Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | | Descriptor: | POTASSIUM ION, SODIUM ION, Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | | Authors: | Ennifar, E. | | Deposit date: | 2020-07-30 | | Release date: | 2020-12-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | 2'- O -Trifluoromethylated RNA - a powerful modification for RNA chemistry and NMR spectroscopy.
Chem Sci, 11, 2020
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6ZYB
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8PUT
 | | IF5A in complex with Deoxyhypusine synthase | | Descriptor: | DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable deoxyhypusine synthase, ... | | Authors: | Ennifar, E, D'agostino, M. | | Deposit date: | 2023-07-17 | | Release date: | 2024-07-03 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of archaeal IF5A-DHS complex reveals insights into the hypusination mechanism.
Structure, 32, 2024
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3ISN
 | | Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor | | Descriptor: | 6-ethenyl-N,N-dimethyl-2-(methylsulfonyl)pyrimidin-4-amine, Reverse transcriptase/ribonuclease H, p51 RT | | Authors: | Ennifar, E, Freisz, S, Bec, G, Dumas, P, Botta, M, Radi, M. | | Deposit date: | 2009-08-26 | | Release date: | 2010-03-16 | | Last modified: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action
Angew.Chem.Int.Ed.Engl., 49, 2010
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