1OU5
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![BU of 1ou5 by Molmil](/molmil-images/mine/1ou5) | Crystal structure of human CCA-adding enzyme | Descriptor: | tRNA CCA-adding enzyme | Authors: | Augustin, M.A, Reichert, A.S, Betat, H, Huber, R, Moerl, M, Steegborn, C. | Deposit date: | 2003-03-24 | Release date: | 2003-05-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization J.Mol.Biol., 328, 2003
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1P3Y
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![BU of 1p3y by Molmil](/molmil-images/mine/1p3y) | MrsD from Bacillus sp. HIL-Y85/54728 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MrsD protein | Authors: | Blaesse, M, Kupke, T, Huber, R, Steinbacher, S. | Deposit date: | 2003-04-19 | Release date: | 2003-08-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structure of MrsD, an FAD-binding protein of the HFCD family. Acta Crystallogr.,Sect.D, 59, 2003
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1P0N
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![BU of 1p0n by Molmil](/molmil-images/mine/1p0n) | IPP:DMAPP isomerase type II, FMN complex | Descriptor: | FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase | Authors: | Steinbacher, S, Kaiser, J, Gerhardt, S, Eisenreich, W, Huber, R, Bacher, A, Rohdich, F. | Deposit date: | 2003-04-10 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase from Bacillus subtilis J.Mol.Biol., 329, 2003
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1JAO
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![BU of 1jao by Molmil](/molmil-images/mine/1jao) | COMPLEX OF 3-MERCAPTO-2-BENZYLPROPANOYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), N-[(2S)-2-benzyl-3-sulfanylpropanoyl]-L-alanylglycinamide, ... | Authors: | Grams, F, Reinemer, P, Powers, J.C, Kleine, T, Piper, M, Tschesche, H, Huber, R, Bode, W. | Deposit date: | 1996-03-11 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. Eur.J.Biochem., 228, 1995
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1JAP
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![BU of 1jap by Molmil](/molmil-images/mine/1jap) | COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), PRO-LEU-GLY-HYDROXYLAMINE, ... | Authors: | Bode, W, Reinemer, P, Huber, R, Kleine, T, Schnierer, S, Tschesche, H. | Deposit date: | 1996-03-11 | Release date: | 1996-07-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. EMBO J., 13, 1994
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1JAN
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![BU of 1jan by Molmil](/molmil-images/mine/1jan) | COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (PHE79 FORM) | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (PHE79 FORM), PRO-LEU-GLY-HYDROXYLAMINE INHIBITOR, ... | Authors: | Reinemer, P, Grams, F, Huber, R, Kleine, T, Schnierer, S, Pieper, M, Tschesche, H, Bode, W. | Deposit date: | 1996-03-11 | Release date: | 1996-07-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural implications for the role of the N terminus in the 'superactivation' of collagenases. A crystallographic study. FEBS Lett., 338, 1994
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1PIX
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![BU of 1pix by Molmil](/molmil-images/mine/1pix) | Crystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme A decarboxylase | Descriptor: | FORMIC ACID, Glutaconyl-CoA decarboxylase A subunit, SULFATE ION | Authors: | Wendt, K.S, Schall, I, Huber, R, Buckel, W, Jacob, U. | Deposit date: | 2003-05-30 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase Embo J., 22, 2003
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1PKQ
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![BU of 1pkq by Molmil](/molmil-images/mine/1pkq) | Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex | Descriptor: | (8-18C5) chimeric Fab, heavy chain, light chain, ... | Authors: | Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2003-06-06 | Release date: | 2003-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein Proc.Natl.Acad.Sci.USA, 100, 2003
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1JAQ
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![BU of 1jaq by Molmil](/molmil-images/mine/1jaq) | COMPLEX OF 1-HYDROXYLAMINE-2-ISOBUTYLMALONYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), N-[(2R)-2-(hydroxycarbamoyl)-4-methylpentanoyl]-L-alanylglycinamide, ... | Authors: | Grams, F, Reinemer, P, Powers, J.C, Kleine, T, Piper, M, Tschesche, H, Huber, R, Bode, W. | Deposit date: | 1996-03-11 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. Eur.J.Biochem., 228, 1995
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1PKO
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![BU of 1pko by Molmil](/molmil-images/mine/1pko) | Myelin Oligodendrocyte Glycoprotein (MOG) | Descriptor: | Myelin Oligodendrocyte Glycoprotein | Authors: | Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2003-06-06 | Release date: | 2003-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein Proc.Natl.Acad.Sci.USA, 100, 2003
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1N05
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![BU of 1n05 by Molmil](/molmil-images/mine/1n05) | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold | Descriptor: | putative Riboflavin kinase | Authors: | Bauer, S, Kemter, K, Bacher, A, Huber, R, Fischer, M, Steinbacher, S. | Deposit date: | 2002-10-11 | Release date: | 2003-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold J.Mol.Biol., 326, 2003
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1N8P
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![BU of 1n8p by Molmil](/molmil-images/mine/1n8p) | Crystal Structure of cystathionine gamma-lyase from yeast | Descriptor: | Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Messerschmidt, A, Worbs, M, Steegborn, C, Wahl, M.C, Huber, R, Clausen, T. | Deposit date: | 2002-11-21 | Release date: | 2002-12-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Determinants of Enzymatic Specificity in the Cys-Met-Metabolism PLP-Dependent Enzymes Family: Crystal Structure of Cystathionine gamma-lyase from Yeast and Intrafamiliar Structural Comparison BIOL.CHEM., 384, 2003
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1OXF
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![BU of 1oxf by Molmil](/molmil-images/mine/1oxf) | Expansion of the Genetic Code Enables Design of a Novel "Gold" Class of Green Fluorescent Proteins | Descriptor: | cyan fluorescent protein cfp | Authors: | Hyun Bae, J, Rubini, M, Jung, G, Wiegand, G, Seifert, M.H, Azim, M.K, Kim, J.S, Zumbusch, A, Holak, T.A, Moroder, L, Huber, R, Budisa, N. | Deposit date: | 2003-04-02 | Release date: | 2003-12-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Expansion of the Genetic Code Enables Design of a Novel "Gold" Class of Green Fluorescent Proteins J.Mol.Biol., 328, 2003
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1ONP
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![BU of 1onp by Molmil](/molmil-images/mine/1onp) | IspC complex with Mn2+ and fosmidomycin | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MANGANESE (II) ION | Authors: | Steinbacher, S, Kaiser, J, Eisenreich, W, Huber, R, Bacher, A, Rohdich, F. | Deposit date: | 2003-02-28 | Release date: | 2003-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol
4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria
drug development. J.BIOL.CHEM., 278, 2003
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1JK3
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![BU of 1jk3 by Molmil](/molmil-images/mine/1jk3) | Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, MACROPHAGE METALLOELASTASE, ... | Authors: | Lang, R, Kocourek, A, Braun, M, Tschesche, H, Huber, R, Bode, W, Maskos, K. | Deposit date: | 2001-07-11 | Release date: | 2001-09-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J.Mol.Biol., 312, 2001
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1QDB
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![BU of 1qdb by Molmil](/molmil-images/mine/1qdb) | CYTOCHROME C NITRITE REDUCTASE | Descriptor: | CALCIUM ION, CYTOCHROME C NITRITE REDUCTASE, HEME C, ... | Authors: | Einsle, O, Messerschmidt, A, Stach, P, Huber, R, Kroneck, P.M.H. | Deposit date: | 1999-05-19 | Release date: | 1999-08-18 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of cytochrome c nitrite reductase. Nature, 400, 1999
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1YDS
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![BU of 1yds by Molmil](/molmil-images/mine/1yds) | Structure of CAMP-dependent protein kinase, alpha-catalytic subunit in complex with H8 protein kinase inhibitor [N-(2-methylamino)ethyl]-5-isoquinolinesulfonamide | Descriptor: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | Authors: | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | Deposit date: | 1996-07-24 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1YDR
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![BU of 1ydr by Molmil](/molmil-images/mine/1ydr) | STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE | Descriptor: | 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, C-AMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR PEPTIDE | Authors: | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | Deposit date: | 1996-07-24 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1YDT
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![BU of 1ydt by Molmil](/molmil-images/mine/1ydt) | STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H89 PROTEIN KINASE INHIBITOR N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE | Descriptor: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | Authors: | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | Deposit date: | 1996-07-24 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1M4Y
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![BU of 1m4y by Molmil](/molmil-images/mine/1m4y) | Crystal structure of HslV from Thermotoga maritima | Descriptor: | ATP-dependent protease hslV, SODIUM ION | Authors: | Song, H.K, Ramachandran, R, Bochtler, M.B, Hartmann, C, Azim, M.K, Huber, R. | Deposit date: | 2002-07-05 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. BIOPHYS.CHEM., 100, 2003
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2NAP
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![BU of 2nap by Molmil](/molmil-images/mine/2nap) | DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Dias, J.M, Than, M, Humm, A, Huber, R, Bourenkov, G, Bartunik, H, Bursakov, S, Calvete, J, Caldeira, J, Carneiro, C, Moura, J, Moura, I, Romao, M.J. | Deposit date: | 1998-09-18 | Release date: | 1999-09-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the first dissimilatory nitrate reductase at 1.9 A solved by MAD methods. Structure Fold.Des., 7, 1999
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2DSP
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![BU of 2dsp by Molmil](/molmil-images/mine/2dsp) | Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins | Descriptor: | Insulin-like growth factor IB, Insulin-like growth factor-binding protein 4 | Authors: | Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. | Deposit date: | 2006-07-05 | Release date: | 2006-08-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1U9L
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![BU of 1u9l by Molmil](/molmil-images/mine/1u9l) | Structural basis for a NusA- protein N interaction | Descriptor: | GOLD ION, Lambda N, Transcription elongation protein nusA | Authors: | Bonin, I, Muehlberger, R, Bourenkov, G.P, Huber, R, Bacher, A, Richter, G, Wahl, M.C. | Deposit date: | 2004-08-10 | Release date: | 2004-08-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the interaction of Escherichia coli NusA with protein N of phage lambda Proc.Natl.Acad.Sci.Usa, 101, 2004
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1TSP
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![BU of 1tsp by Molmil](/molmil-images/mine/1tsp) | CRYSTAL STRUCTURE OF P22 TAILSPIKE PROTEIN: INTERDIGITATED SUBUNITS IN A THERMOSTABLE TRIMER | Descriptor: | TAILSPIKE-PROTEIN | Authors: | Steinbacher, S, Seckler, R, Miller, S, Steipe, B, Huber, R, Reinemer, P. | Deposit date: | 1994-06-16 | Release date: | 1995-09-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science, 265, 1994
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1KLO
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![BU of 1klo by Molmil](/molmil-images/mine/1klo) | |