3QGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qgm by Molmil](/molmil-images/mine/3qgm) | p-nitrophenyl phosphatase from Archaeoglobus fulgidus | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, p-nitrophenyl phosphatase (Pho2) | Authors: | Osipiuk, J, Zheng, H, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-01-24 | Release date: | 2011-02-09 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | p-nitrophenyl phosphatase from Archaeoglobus fulgidus. To be Published
|
|
2BIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bik by Molmil](/molmil-images/mine/2bik) | Human Pim1 phosphorylated on Ser261 | Descriptor: | 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, CHLORIDE ION, PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1 | Authors: | Knapp, S, Debreczeni, J, Bullock, A, von Delft, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Guo, K. | Deposit date: | 2005-01-22 | Release date: | 2005-02-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Human Pim1 Phosphorylated on Ser261 To be Published
|
|
2C9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c9y by Molmil](/molmil-images/mine/2c9y) | Structure of human adenylate kinase 2 | Descriptor: | 1,2-ETHANEDIOL, ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL, ... | Authors: | Bunkoczi, G, Filippakopoulos, P, Debreczeni, J.E, Turnbull, A, Papagrigoriou, E, Savitsky, P, Colebrook, S, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Knapp, S. | Deposit date: | 2005-12-15 | Release date: | 2006-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Human Adenylate Kinase 2 To be Published
|
|
5CLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5clt by Molmil](/molmil-images/mine/5clt) | Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose | Descriptor: | 1,4-alpha-glucan-branching enzyme, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Krojer, T, Froese, D.S, Goubin, S, Strain-Damerell, C, Mahajan, P, Burgess-Brown, N, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Yue, W, Structural Genomics Consortium (SGC) | Deposit date: | 2015-07-16 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose To be published
|
|
1ZS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zs6 by Molmil](/molmil-images/mine/1zs6) | structure of human nucleoside-diphosphate kinase 3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3 | Authors: | Choe, J, Dimov, S, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2005-05-23 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of human nucleoside-diphosphate kinase 3 To be Published
|
|
1ZX1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zx1 by Molmil](/molmil-images/mine/1zx1) | Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954 | Descriptor: | 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, NRH dehydrogenase [quinone] 2, ... | Authors: | Jansson, A, Wu, X, Kavanagh, K, Kerr, D, Knox, R, Walton, R, Gunther, U, Ludwig, C, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2005-06-06 | Release date: | 2005-06-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954 To be Published
|
|
2AWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2awg by Molmil](/molmil-images/mine/2awg) | Structure of the PPIase domain of the Human FK506-binding protein 8 | Descriptor: | 38 kDa FK-506 binding protein | Authors: | Walker, J.R, Davis, T, Newman, E.M, Finerty, P, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-09-01 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the human FK-506 binding protein 8 To be Published
|
|
4CUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cuu by Molmil](/molmil-images/mine/4cuu) | Crystal structure of human BAZ2B in complex with fragment-6 N09645 | Descriptor: | (2R)-1,2,3,4-tetrahydroquinoline-2,7-diol, 1,2-ETHANEDIOL, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B | Authors: | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | Deposit date: | 2014-03-21 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Crystal Structure of Human Baz2B in Complex with Fragment-6 N09645 To be Published
|
|
2B05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b05 by Molmil](/molmil-images/mine/2b05) | Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide | Descriptor: | 14-3-3 protein gamma, peptide | Authors: | Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X. | Deposit date: | 2005-09-13 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide TO BE PUBLISHED
|
|
2BLE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ble by Molmil](/molmil-images/mine/2ble) | Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP | Descriptor: | GMP REDUCTASE I, GUANOSINE-5'-MONOPHOSPHATE, SODIUM ION | Authors: | Bunkoczi, G, Haroniti, A, Ng, S, von Delft, F, Oppermann, U, Arrowsmith, C, Sundstrom, M, Edwards, A, Gileadi, O. | Deposit date: | 2005-03-03 | Release date: | 2005-03-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp To be Published
|
|
4CUS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cus by Molmil](/molmil-images/mine/4cus) | Crystal structure of human BAZ2B in complex with fragment-4 N09496 | Descriptor: | 1,2-ETHANEDIOL, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, quinolin-4-ol | Authors: | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | Deposit date: | 2014-03-21 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | Crystal Structure of Human Baz2B in Complex with Fragment-4 N09496 To be Published
|
|
4CUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cuq by Molmil](/molmil-images/mine/4cuq) | Crystal structure of human BAZ2B in complex with fragment-2 N09594 | Descriptor: | 4-[(3S)-3-hydroxy-3-methoxypropyl]phenol, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B | Authors: | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | Deposit date: | 2014-03-21 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal Structure of Human Baz2B in Complex with Fragment-2 N09594 To be Published
|
|
4CUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cup by Molmil](/molmil-images/mine/4cup) | Crystal structure of human BAZ2B in complex with fragment-1 N09421 | Descriptor: | 4-Fluorobenzamidoxime, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, METHANOL | Authors: | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | Deposit date: | 2014-03-21 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal Structure of Human Baz2B in Complex with Fragment-1 N09421 To be Published
|
|
3RAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rao by Molmil](/molmil-images/mine/3rao) | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. | Descriptor: | Putative Luciferase-like Monooxygenase, SULFATE ION | Authors: | Domagalski, M.J, Chruszcz, M, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-03-28 | Release date: | 2011-05-11 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. To be Published
|
|
3QUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3quf by Molmil](/molmil-images/mine/3quf) | The structure of a family 1 extracellular solute-binding protein from Bifidobacterium longum subsp. infantis | Descriptor: | ACETIC ACID, Extracellular solute-binding protein, family 1, ... | Authors: | Cuff, M.E, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-23 | Release date: | 2011-05-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of a family 1 extracellular solute-binding protein from Bifidobacterium longum subsp. infantis TO BE PUBLISHED
|
|
3QVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qvo by Molmil](/molmil-images/mine/3qvo) | Structure of a Rossmann-fold NAD(P)-binding family protein from Shigella flexneri. | Descriptor: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, NmrA family protein | Authors: | Cuff, M.E, Xu, X, Cui, H, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-25 | Release date: | 2011-06-01 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a Rossmann-fold NAD(P)-binding family protein from Shigella flexneri. TO BE PUBLISHED
|
|
2C95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c95 by Molmil](/molmil-images/mine/2c95) | Structure of adenylate kinase 1 in complex with P1,P4-di(adenosine) tetraphosphate | Descriptor: | ADENYLATE KINASE 1, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, MALONATE ION | Authors: | Bunkoczi, G, Filippakopoulos, P, Jansson, A, Longman, E, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S. | Deposit date: | 2005-12-09 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structure of Adenylate Kinase 1 in Complex with P1, P4-Di(Adenosine)Tetraphosphate To be Published
|
|
2CLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2clp by Molmil](/molmil-images/mine/2clp) | Crystal structure of human aflatoxin B1 aldehyde reductase member 3 | Descriptor: | AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, CALCIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Debreczeni, J.E, Marsden, B.D, Johansson, C, Kavanagh, K, Guo, K, Smee, C, Gileadi, O, Turnbull, A, Papagrigoriou, E, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Oppermann, U. | Deposit date: | 2006-04-28 | Release date: | 2006-05-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Human Aflatoxin B1 Aldehyde Reductase Member 3 To be Published
|
|
4CUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cur by Molmil](/molmil-images/mine/4cur) | Crystal structure of human BAZ2B in complex with fragment-3 N09555 | Descriptor: | 1,2-ETHANEDIOL, 2-(hydroxymethyl)-6-methylpyridin-3-ol, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B | Authors: | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | Deposit date: | 2014-03-21 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.842 Å) | Cite: | Crystal Structure of Human Baz2B in Complex with Fragment-3 N09553 To be Published
|
|
2AX4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ax4 by Molmil](/molmil-images/mine/2ax4) | Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 | Authors: | Rabeh, W.M, Nedyalkova, L, Ismail, S, Park, H, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-09-02 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the kinase domain of PAPSS 2 To be Published
|
|
3QTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qtd by Molmil](/molmil-images/mine/3qtd) | Crystal structure of putative modulator of gyrase (PmbA) from Pseudomonas aeruginosa PAO1 | Descriptor: | GLYCEROL, PmbA protein | Authors: | Tkaczuk, K.L, Chruszcz, M, Evdokimova, E, Liu, F, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-22 | Release date: | 2011-03-30 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of putative modulator of gyrase (PmbA) from Pseudomonas aeruginosa PAO1 To be Published
|
|
2WZS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wzs by Molmil](/molmil-images/mine/2wzs) | Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole | Descriptor: | (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Zhu, Y, Suits, M.D.L, Thompson, A, Chavan, S, Dinev, Z, Dumon, C, Smith, N, Moremen, K.W, Xiang, Y, Siriwardena, A, Williams, S.J, Gilbert, H.J, Davies, G.J. | Deposit date: | 2009-12-02 | Release date: | 2009-12-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
|
|
3S9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s9x by Molmil](/molmil-images/mine/3s9x) | High resolution crystal structure of ASCH domain from Lactobacillus crispatus JV V101 | Descriptor: | ASCH domain, CHLORIDE ION | Authors: | Nocek, B, Xu, X, Cui, H, Jedrzejczak, R, Edwards, A, Savchenko, A, Mabbutt, B.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-06-02 | Release date: | 2011-07-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | High resolution crystal structure of ASCH domain from Lactobacillus crispatus JV V101 TO BE PUBLISHED
|
|
1TD5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1td5 by Molmil](/molmil-images/mine/1td5) | Crystal Structure of the Ligand Binding Domain of E. coli IclR. | Descriptor: | Acetate operon repressor | Authors: | Walker, J.R, Evdokimova, L, Zhang, R.-G, Bochkarev, A, Joachimiak, A, Arrowsmith, C, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-05-21 | Release date: | 2004-07-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analyses of the Ligand Binding Sites of the IclR family of transcriptional regulators To be Published
|
|
3ON1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3on1 by Molmil](/molmil-images/mine/3on1) | The structure of a protein with unknown function from Bacillus halodurans C | Descriptor: | BH2414 protein | Authors: | Fan, Y, Kagan, O, Savchenko, A, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-08-27 | Release date: | 2010-09-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure of a protein with unknown function from Bacillus halodurans C To be Published
|
|