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1EYM
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BU of 1eym by Molmil
FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX
Descriptor: FK506 BINDING PROTEIN
Authors:Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T.
Deposit date:2000-05-07
Release date:2000-08-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:A ligand-reversible dimerization system for controlling protein-protein interactions.
Proc.Natl.Acad.Sci.USA, 97, 2000
8I5C
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BU of 8i5c by Molmil
Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Descriptor: Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ...
Authors:Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
Deposit date:2023-01-24
Release date:2023-08-23
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
8I5E
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BU of 8i5e by Molmil
Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVGAGGVGK)
Descriptor: Beta-2-microglobulin, KRAS-G12wt-9, MHC class I antigen (Fragment)
Authors:Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
Deposit date:2023-01-25
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
8IMX
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BU of 8imx by Molmil
Cryo-EM structure of GPI-T with a chimeric GPI-anchored protein
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, Y, Li, T, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
8IM5
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BU of 8im5 by Molmil
Solution structure of the mouse HOIL1-L NZF domain in the free form
Descriptor: RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION
Authors:Walinda, E, Morimoto, D.
Deposit date:2023-03-06
Release date:2023-08-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity.
J.Biol.Chem., 299, 2023
8IHS
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BU of 8ihs by Molmil
Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3 in complex with ochratoxin A
Descriptor: (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid, Amidohydrolase family protein, ZINC ION
Authors:Dai, L.H, Niu, D, Huang, J.-W, Li, X, Shen, P.P, Li, H, Hu, Y.M, Yang, Y, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-23
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase.
J Hazard Mater, 458, 2023
1EF1
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BU of 1ef1 by Molmil
CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor: MOESIN, SULFATE ION
Authors:Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
8IMY
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BU of 8imy by Molmil
Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T, Xu, Y, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
1EQU
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BU of 1equ by Molmil
TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+
Descriptor: EQUILIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1)
Authors:Sawicki, M.W, Erman, M, Puranen, T, Vihko, P, Ghosh, D.
Deposit date:1998-12-02
Release date:1999-12-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Proc.Natl.Acad.Sci.USA, 96, 1999
8IHR
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BU of 8ihr by Molmil
Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3 in complex with Phe
Descriptor: Amidohydrolase family protein, PHENYLALANINE, ZINC ION
Authors:Dai, L.H, Niu, D, Huang, J.-W, Li, X, Shen, P.P, Li, H, Hu, Y.M, Yang, Y, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-23
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase.
J Hazard Mater, 458, 2023
1EJM
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BU of 1ejm by Molmil
CRYSTAL STRUCTURE OF THE BPTI ALA16LEU MUTANT IN COMPLEX WITH BOVINE TRYPSIN
Descriptor: BETA-TRYPSIN, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
Authors:Otlewski, J, Smalas, A, Helland, R, Grzesiak, A, Krowarsch, D.
Deposit date:2000-03-03
Release date:2001-03-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases.
J.Mol.Biol., 301, 2000
8IHQ
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BU of 8ihq by Molmil
Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3
Descriptor: Amidohydrolase family protein, ZINC ION
Authors:Dai, L.H, Niu, D, Huang, J.-W, Li, X, Shen, P.P, Li, H, Hu, Y.M, Yang, Y, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-23
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase.
J Hazard Mater, 458, 2023
8IGC
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BU of 8igc by Molmil
Crystal structure of Bak bound to Bnip5 BH3
Descriptor: Bcl-2 homologous antagonist/killer, Protein BNIP5
Authors:Ku, B, Lim, D.
Deposit date:2023-02-20
Release date:2023-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:Crystal structure of Bak bound to the BH3 domain of Bnip5, a noncanonical BH3 domain-containing protein.
Proteins, 92, 2024
1EXP
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BU of 1exp by Molmil
BETA-1,4-GLYCANASE CEX-CD
Descriptor: BETA-1,4-D-GLYCANASE CEX-CD, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose
Authors:White, A, Tull, D, Johns, K.L, Withers, S.G, Rose, D.R.
Deposit date:1996-01-11
Release date:1997-01-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic observation of a covalent catalytic intermediate in a beta-glycosidase.
Nat.Struct.Biol., 3, 1996
5ABY
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BU of 5aby by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
Descriptor: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
8IBO
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BU of 8ibo by Molmil
Crystal structure of Wild-Type Mycobacterium tuberculosis ClpC1 N-terminal domain in complex with Lassomycin
Descriptor: ACETATE ION, Lassomycin, Negative regulator of genetic competence ClpC/mecB
Authors:Jagdev, M.K, Vasudevan, D.
Deposit date:2023-02-10
Release date:2023-09-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin.
Int.J.Biol.Macromol., 253, 2023
1EF7
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BU of 1ef7 by Molmil
CRYSTAL STRUCTURE OF HUMAN CATHEPSIN X
Descriptor: CATHEPSIN X
Authors:Guncar, G, Klemencic, I, Turk, B, Turk, V, Karaoglanovic-Carmona, A, Juliano, L, Turk, D.
Deposit date:2000-02-07
Release date:2000-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease.
Structure Fold.Des., 8, 2000
8IBP
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BU of 8ibp by Molmil
Crystal structure of Mycobacterium tuberculosis R21K ClpC1 N-terminal domain in complex with Lassomycin
Descriptor: ACETATE ION, Lassomycin, Negative regulator of genetic competence ClpC/mecB
Authors:Jagdev, M.K, Vasudevan, D.
Deposit date:2023-02-10
Release date:2023-09-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin.
Int.J.Biol.Macromol., 253, 2023
1E5G
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BU of 1e5g by Molmil
Solution structure of central CP module pair of a pox virus complement inhibitor
Descriptor: COMPLEMENT CONTROL PROTEIN C3
Authors:Henderson, C.E, Bromek, K, Mullin, N.P, Smith, B.O, Uhrin, D, Barlow, P.N.
Deposit date:2000-07-25
Release date:2000-08-31
Last modified:2013-07-03
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Central Ccp Module Pair of a Poxvirus Complement Control Protein
J.Mol.Biol., 307, 2001
1EI6
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BU of 1ei6 by Molmil
CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE
Descriptor: L(+)-TARTARIC ACID, PHOSPHONOACETATE HYDROLASE, PHOSPHONOFORMIC ACID, ...
Authors:Holden, H.M, Benning, M.M, Dunaway-Mariano, D, Kim, A.D.
Deposit date:2000-02-24
Release date:2003-11-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Phosphonoacetate Hydrolase complexed with phosphonoformate
To be Published
1EJP
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BU of 1ejp by Molmil
SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN
Descriptor: SYNDECAN-4
Authors:Lee, D, Oh, E.S, Woods, A, Couchman, J.R, Lee, W.
Deposit date:2000-03-03
Release date:2001-09-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the dimeric cytoplasmic domain of syndecan-4.
Biochemistry, 40, 2001
1EKY
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BU of 1eky by Molmil
MODEL STRUCTURE FROM NON-NOE BASED NMR STRUCTURE CALCULATION
Descriptor: CYTOCHROME C', PROTOPORPHYRIN IX CONTAINING FE
Authors:Hus, J.C, Marion, D, Blackledge, M.
Deposit date:2000-03-10
Release date:2000-03-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:De novo determination of protein structure by NMR using orientational and long-range order restraints.
J.Mol.Biol., 298, 2000
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
5IA1
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BU of 5ia1 by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with MLN8054
Descriptor: 1,2-ETHANEDIOL, 4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID, Ephrin type-A receptor 2
Authors:Kudlinzki, D, Linhard, V.L, Gande, S.L, Sreeramulu, S, Saxena, K, Heinzlmeir, S, Medard, G, Kuester, B, Schwalbe, H.
Deposit date:2016-02-21
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
ACS Chem. Biol., 11, 2016

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