6ZHE

Cryo-EM structure of DNA-PK dimer

Summary for 6ZHE

Entry DOI	10.2210/pdb6zhe/pdb
EMDB information	11219
Descriptor	DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (7 entities in total)
Functional Keywords	kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein, ku70/80
Biological source	Homo sapiens (Human) More
Total number of polymer chains	10
Total formula weight	1282306.80
Authors	Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2020-06-23, release date: 2020-10-21, Last modification date: 2021-01-20)
Primary citation	Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L. Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28:13-19, 2021 Cited by PubMed: 33077952 DOI: 10.1038/s41594-020-00517-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (7.24 Å)

Structure validation