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6ZHE

Cryo-EM structure of DNA-PK dimer

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000460biological_processmaturation of 5.8S rRNA
A0000723biological_processtelomere maintenance
A0000781cellular_componentchromosome, telomeric region
A0000785cellular_componentchromatin
A0001756biological_processsomitogenesis
A0001933biological_processnegative regulation of protein phosphorylation
A0002218biological_processactivation of innate immune response
A0002326biological_processB cell lineage commitment
A0002327biological_processimmature B cell differentiation
A0002328biological_processpro-B cell differentiation
A0002360biological_processT cell lineage commitment
A0002376biological_processimmune system process
A0003677molecular_functionDNA binding
A0003690molecular_functiondouble-stranded DNA binding
A0003723molecular_functionRNA binding
A0004672molecular_functionprotein kinase activity
A0004674molecular_functionprotein serine/threonine kinase activity
A0004677molecular_functionDNA-dependent protein kinase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005667cellular_componenttranscription regulator complex
A0005730cellular_componentnucleolus
A0005829cellular_componentcytosol
A0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
A0006281biological_processDNA repair
A0006302biological_processdouble-strand break repair
A0006303biological_processdouble-strand break repair via nonhomologous end joining
A0006310biological_processDNA recombination
A0006338biological_processchromatin remodeling
A0006468biological_processprotein phosphorylation
A0006974biological_processDNA damage response
A0007420biological_processbrain development
A0007507biological_processheart development
A0008630biological_processintrinsic apoptotic signaling pathway in response to DNA damage
A0010212biological_processresponse to ionizing radiation
A0010332biological_processresponse to gamma radiation
A0016020cellular_componentmembrane
A0016043biological_processcellular component organization
A0016233biological_processtelomere capping
A0016301molecular_functionkinase activity
A0016310biological_processphosphorylation
A0016740molecular_functiontransferase activity
A0018105biological_processpeptidyl-serine phosphorylation
A0018107biological_processpeptidyl-threonine phosphorylation
A0019899molecular_functionenzyme binding
A0019904molecular_functionprotein domain specific binding
A0030098biological_processlymphocyte differentiation
A0031571biological_processmitotic G1 DNA damage checkpoint signaling
A0031648biological_processprotein destabilization
A0032040cellular_componentsmall-subunit processome
A0032869biological_processcellular response to insulin stimulus
A0032991cellular_componentprotein-containing complex
A0032993cellular_componentprotein-DNA complex
A0033077biological_processT cell differentiation in thymus
A0033151biological_processV(D)J recombination
A0033152biological_processimmunoglobulin V(D)J recombination
A0033153biological_processT cell receptor V(D)J recombination
A0034462biological_processsmall-subunit processome assembly
A0034511molecular_functionU3 snoRNA binding
A0035234biological_processectopic germ cell programmed cell death
A0035979molecular_functionhistone H2AXS139 kinase activity
A0036211biological_processprotein modification process
A0042254biological_processribosome biogenesis
A0042752biological_processregulation of circadian rhythm
A0043065biological_processpositive regulation of apoptotic process
A0043066biological_processnegative regulation of apoptotic process
A0045087biological_processinnate immune response
A0045621biological_processpositive regulation of lymphocyte differentiation
A0045648biological_processpositive regulation of erythrocyte differentiation
A0045727biological_processpositive regulation of translation
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0048511biological_processrhythmic process
A0048584biological_processpositive regulation of response to stimulus
A0048660biological_processregulation of smooth muscle cell proliferation
A0050678biological_processregulation of epithelial cell proliferation
A0051171biological_processobsolete regulation of nitrogen compound metabolic process
A0060255biological_processregulation of macromolecule metabolic process
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
A0070418cellular_componentDNA-dependent protein kinase complex
A0070419cellular_componentnonhomologous end joining complex
A0080090biological_processregulation of primary metabolic process
A0080135biological_processregulation of cellular response to stress
A0097681biological_processdouble-strand break repair via alternative nonhomologous end joining
A0106310molecular_functionprotein serine kinase activity
A0160049biological_processnegative regulation of cGAS/STING signaling pathway
A1902036biological_processregulation of hematopoietic stem cell differentiation
A1905221biological_processpositive regulation of platelet formation
A2001034biological_processpositive regulation of double-strand break repair via nonhomologous end joining
B0000166molecular_functionnucleotide binding
B0000723biological_processtelomere maintenance
B0000725biological_processrecombinational repair
B0000781cellular_componentchromosome, telomeric region
B0000783cellular_componentnuclear telomere cap complex
B0000976molecular_functiontranscription cis-regulatory region binding
B0002218biological_processactivation of innate immune response
B0002376biological_processimmune system process
B0003677molecular_functionDNA binding
B0003678molecular_functionDNA helicase activity
B0003684molecular_functiondamaged DNA binding
B0003690molecular_functiondouble-stranded DNA binding
B0003691molecular_functiondouble-stranded telomeric DNA binding
B0003723molecular_functionRNA binding
B0003824molecular_functioncatalytic activity
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005667cellular_componenttranscription regulator complex
B0005694cellular_componentchromosome
B0005730cellular_componentnucleolus
B0005829cellular_componentcytosol
B0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
B0006266biological_processDNA ligation
B0006281biological_processDNA repair
B0006303biological_processdouble-strand break repair via nonhomologous end joining
B0006310biological_processDNA recombination
B0006974biological_processDNA damage response
B0008094molecular_functionATP-dependent activity, acting on DNA
B0008152biological_processmetabolic process
B0010558biological_processnegative regulation of macromolecule biosynthetic process
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0016829molecular_functionlyase activity
B0016887molecular_functionATP hydrolysis activity
B0030332molecular_functioncyclin binding
B0032508biological_processDNA duplex unwinding
B0032991cellular_componentprotein-containing complex
B0032993cellular_componentprotein-DNA complex
B0034774cellular_componentsecretory granule lumen
B0042162molecular_functiontelomeric DNA binding
B0043229cellular_componentintracellular organelle
B0043564cellular_componentKu70:Ku80 complex
B0044877molecular_functionprotein-containing complex binding
B0045027molecular_functionDNA end binding
B0045087biological_processinnate immune response
B0045621biological_processpositive regulation of lymphocyte differentiation
B0045860biological_processpositive regulation of protein kinase activity
B0045892biological_processnegative regulation of DNA-templated transcription
B0045893biological_processpositive regulation of DNA-templated transcription
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0048660biological_processregulation of smooth muscle cell proliferation
B0051575molecular_function5'-deoxyribose-5-phosphate lyase activity
B0070418cellular_componentDNA-dependent protein kinase complex
B0070419cellular_componentnonhomologous end joining complex
B0071475biological_processcellular hyperosmotic salinity response
B0071480biological_processcellular response to gamma radiation
B0071481biological_processcellular response to X-ray
B0097110molecular_functionscaffold protein binding
B0097680biological_processdouble-strand break repair via classical nonhomologous end joining
B1904813cellular_componentficolin-1-rich granule lumen
C0000166molecular_functionnucleotide binding
C0000723biological_processtelomere maintenance
C0000725biological_processrecombinational repair
C0000781cellular_componentchromosome, telomeric region
C0000783cellular_componentnuclear telomere cap complex
C0000976molecular_functiontranscription cis-regulatory region binding
C0002218biological_processactivation of innate immune response
C0002376biological_processimmune system process
C0003677molecular_functionDNA binding
C0003678molecular_functionDNA helicase activity
C0003684molecular_functiondamaged DNA binding
C0003690molecular_functiondouble-stranded DNA binding
C0003691molecular_functiondouble-stranded telomeric DNA binding
C0003723molecular_functionRNA binding
C0004386molecular_functionhelicase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005576cellular_componentextracellular region
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005694cellular_componentchromosome
C0005730cellular_componentnucleolus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
C0006281biological_processDNA repair
C0006302biological_processdouble-strand break repair
C0006303biological_processdouble-strand break repair via nonhomologous end joining
C0006310biological_processDNA recombination
C0006974biological_processDNA damage response
C0008047molecular_functionenzyme activator activity
C0008094molecular_functionATP-dependent activity, acting on DNA
C0009410biological_processresponse to xenobiotic stimulus
C0010558biological_processnegative regulation of macromolecule biosynthetic process
C0016020cellular_componentmembrane
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0022008biological_processneurogenesis
C0031625molecular_functionubiquitin protein ligase binding
C0032040cellular_componentsmall-subunit processome
C0032204biological_processregulation of telomere maintenance
C0032212biological_processpositive regulation of telomere maintenance via telomerase
C0032508biological_processDNA duplex unwinding
C0032991cellular_componentprotein-containing complex
C0032993cellular_componentprotein-DNA complex
C0034462biological_processsmall-subunit processome assembly
C0034511molecular_functionU3 snoRNA binding
C0034774cellular_componentsecretory granule lumen
C0042162molecular_functiontelomeric DNA binding
C0042254biological_processribosome biogenesis
C0043085biological_processpositive regulation of catalytic activity
C0043229cellular_componentintracellular organelle
C0043564cellular_componentKu70:Ku80 complex
C0044877molecular_functionprotein-containing complex binding
C0045027molecular_functionDNA end binding
C0045087biological_processinnate immune response
C0045860biological_processpositive regulation of protein kinase activity
C0045892biological_processnegative regulation of DNA-templated transcription
C0048660biological_processregulation of smooth muscle cell proliferation
C0050769biological_processpositive regulation of neurogenesis
C0051575molecular_function5'-deoxyribose-5-phosphate lyase activity
C0051973biological_processpositive regulation of telomerase activity
C0060218biological_processhematopoietic stem cell differentiation
C0070198biological_processprotein localization to chromosome, telomeric region
C0070418cellular_componentDNA-dependent protein kinase complex
C0070419cellular_componentnonhomologous end joining complex
C0071398biological_processcellular response to fatty acid
C0071425biological_processhematopoietic stem cell proliferation
C0071475biological_processcellular hyperosmotic salinity response
C0071480biological_processcellular response to gamma radiation
C0071481biological_processcellular response to X-ray
C0090734cellular_componentsite of DNA damage
C1904430biological_processnegative regulation of t-circle formation
C1990830biological_processcellular response to leukemia inhibitory factor
C1990904cellular_componentribonucleoprotein complex
F0000166molecular_functionnucleotide binding
F0000460biological_processmaturation of 5.8S rRNA
F0000723biological_processtelomere maintenance
F0000781cellular_componentchromosome, telomeric region
F0000785cellular_componentchromatin
F0001756biological_processsomitogenesis
F0001933biological_processnegative regulation of protein phosphorylation
F0002218biological_processactivation of innate immune response
F0002326biological_processB cell lineage commitment
F0002327biological_processimmature B cell differentiation
F0002328biological_processpro-B cell differentiation
F0002360biological_processT cell lineage commitment
F0002376biological_processimmune system process
F0003677molecular_functionDNA binding
F0003690molecular_functiondouble-stranded DNA binding
F0003723molecular_functionRNA binding
F0004672molecular_functionprotein kinase activity
F0004674molecular_functionprotein serine/threonine kinase activity
F0004677molecular_functionDNA-dependent protein kinase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005667cellular_componenttranscription regulator complex
F0005730cellular_componentnucleolus
F0005829cellular_componentcytosol
F0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
F0006281biological_processDNA repair
F0006302biological_processdouble-strand break repair
F0006303biological_processdouble-strand break repair via nonhomologous end joining
F0006310biological_processDNA recombination
F0006338biological_processchromatin remodeling
F0006468biological_processprotein phosphorylation
F0006974biological_processDNA damage response
F0007420biological_processbrain development
F0007507biological_processheart development
F0008630biological_processintrinsic apoptotic signaling pathway in response to DNA damage
F0010212biological_processresponse to ionizing radiation
F0010332biological_processresponse to gamma radiation
F0016020cellular_componentmembrane
F0016043biological_processcellular component organization
F0016233biological_processtelomere capping
F0016301molecular_functionkinase activity
F0016310biological_processphosphorylation
F0016740molecular_functiontransferase activity
F0018105biological_processpeptidyl-serine phosphorylation
F0018107biological_processpeptidyl-threonine phosphorylation
F0019899molecular_functionenzyme binding
F0019904molecular_functionprotein domain specific binding
F0030098biological_processlymphocyte differentiation
F0031571biological_processmitotic G1 DNA damage checkpoint signaling
F0031648biological_processprotein destabilization
F0032040cellular_componentsmall-subunit processome
F0032869biological_processcellular response to insulin stimulus
F0032991cellular_componentprotein-containing complex
F0032993cellular_componentprotein-DNA complex
F0033077biological_processT cell differentiation in thymus
F0033151biological_processV(D)J recombination
F0033152biological_processimmunoglobulin V(D)J recombination
F0033153biological_processT cell receptor V(D)J recombination
F0034462biological_processsmall-subunit processome assembly
F0034511molecular_functionU3 snoRNA binding
F0035234biological_processectopic germ cell programmed cell death
F0035979molecular_functionhistone H2AXS139 kinase activity
F0036211biological_processprotein modification process
F0042254biological_processribosome biogenesis
F0042752biological_processregulation of circadian rhythm
F0043065biological_processpositive regulation of apoptotic process
F0043066biological_processnegative regulation of apoptotic process
F0045087biological_processinnate immune response
F0045621biological_processpositive regulation of lymphocyte differentiation
F0045648biological_processpositive regulation of erythrocyte differentiation
F0045727biological_processpositive regulation of translation
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0048511biological_processrhythmic process
F0048584biological_processpositive regulation of response to stimulus
F0048660biological_processregulation of smooth muscle cell proliferation
F0050678biological_processregulation of epithelial cell proliferation
F0051171biological_processobsolete regulation of nitrogen compound metabolic process
F0060255biological_processregulation of macromolecule metabolic process
F0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
F0070418cellular_componentDNA-dependent protein kinase complex
F0070419cellular_componentnonhomologous end joining complex
F0080090biological_processregulation of primary metabolic process
F0080135biological_processregulation of cellular response to stress
F0097681biological_processdouble-strand break repair via alternative nonhomologous end joining
F0106310molecular_functionprotein serine kinase activity
F0160049biological_processnegative regulation of cGAS/STING signaling pathway
F1902036biological_processregulation of hematopoietic stem cell differentiation
F1905221biological_processpositive regulation of platelet formation
F2001034biological_processpositive regulation of double-strand break repair via nonhomologous end joining
G0000166molecular_functionnucleotide binding
G0000723biological_processtelomere maintenance
G0000725biological_processrecombinational repair
G0000781cellular_componentchromosome, telomeric region
G0000783cellular_componentnuclear telomere cap complex
G0000976molecular_functiontranscription cis-regulatory region binding
G0002218biological_processactivation of innate immune response
G0002376biological_processimmune system process
G0003677molecular_functionDNA binding
G0003678molecular_functionDNA helicase activity
G0003684molecular_functiondamaged DNA binding
G0003690molecular_functiondouble-stranded DNA binding
G0003691molecular_functiondouble-stranded telomeric DNA binding
G0003723molecular_functionRNA binding
G0003824molecular_functioncatalytic activity
G0004386molecular_functionhelicase activity
G0005515molecular_functionprotein binding
G0005524molecular_functionATP binding
G0005576cellular_componentextracellular region
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005667cellular_componenttranscription regulator complex
G0005694cellular_componentchromosome
G0005730cellular_componentnucleolus
G0005829cellular_componentcytosol
G0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
G0006266biological_processDNA ligation
G0006281biological_processDNA repair
G0006303biological_processdouble-strand break repair via nonhomologous end joining
G0006310biological_processDNA recombination
G0006974biological_processDNA damage response
G0008094molecular_functionATP-dependent activity, acting on DNA
G0008152biological_processmetabolic process
G0010558biological_processnegative regulation of macromolecule biosynthetic process
G0016020cellular_componentmembrane
G0016787molecular_functionhydrolase activity
G0016829molecular_functionlyase activity
G0016887molecular_functionATP hydrolysis activity
G0030332molecular_functioncyclin binding
G0032508biological_processDNA duplex unwinding
G0032991cellular_componentprotein-containing complex
G0032993cellular_componentprotein-DNA complex
G0034774cellular_componentsecretory granule lumen
G0042162molecular_functiontelomeric DNA binding
G0043229cellular_componentintracellular organelle
G0043564cellular_componentKu70:Ku80 complex
G0044877molecular_functionprotein-containing complex binding
G0045027molecular_functionDNA end binding
G0045087biological_processinnate immune response
G0045621biological_processpositive regulation of lymphocyte differentiation
G0045860biological_processpositive regulation of protein kinase activity
G0045892biological_processnegative regulation of DNA-templated transcription
G0045893biological_processpositive regulation of DNA-templated transcription
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0048660biological_processregulation of smooth muscle cell proliferation
G0051575molecular_function5'-deoxyribose-5-phosphate lyase activity
G0070418cellular_componentDNA-dependent protein kinase complex
G0070419cellular_componentnonhomologous end joining complex
G0071475biological_processcellular hyperosmotic salinity response
G0071480biological_processcellular response to gamma radiation
G0071481biological_processcellular response to X-ray
G0097110molecular_functionscaffold protein binding
G0097680biological_processdouble-strand break repair via classical nonhomologous end joining
G1904813cellular_componentficolin-1-rich granule lumen
H0000166molecular_functionnucleotide binding
H0000723biological_processtelomere maintenance
H0000725biological_processrecombinational repair
H0000781cellular_componentchromosome, telomeric region
H0000783cellular_componentnuclear telomere cap complex
H0000976molecular_functiontranscription cis-regulatory region binding
H0002218biological_processactivation of innate immune response
H0002376biological_processimmune system process
H0003677molecular_functionDNA binding
H0003678molecular_functionDNA helicase activity
H0003684molecular_functiondamaged DNA binding
H0003690molecular_functiondouble-stranded DNA binding
H0003691molecular_functiondouble-stranded telomeric DNA binding
H0003723molecular_functionRNA binding
H0004386molecular_functionhelicase activity
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005576cellular_componentextracellular region
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005694cellular_componentchromosome
H0005730cellular_componentnucleolus
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0005958cellular_componentDNA-dependent protein kinase-DNA ligase 4 complex
H0006281biological_processDNA repair
H0006302biological_processdouble-strand break repair
H0006303biological_processdouble-strand break repair via nonhomologous end joining
H0006310biological_processDNA recombination
H0006974biological_processDNA damage response
H0008047molecular_functionenzyme activator activity
H0008094molecular_functionATP-dependent activity, acting on DNA
H0009410biological_processresponse to xenobiotic stimulus
H0010558biological_processnegative regulation of macromolecule biosynthetic process
H0016020cellular_componentmembrane
H0016787molecular_functionhydrolase activity
H0016887molecular_functionATP hydrolysis activity
H0022008biological_processneurogenesis
H0031625molecular_functionubiquitin protein ligase binding
H0032040cellular_componentsmall-subunit processome
H0032204biological_processregulation of telomere maintenance
H0032212biological_processpositive regulation of telomere maintenance via telomerase
H0032508biological_processDNA duplex unwinding
H0032991cellular_componentprotein-containing complex
H0032993cellular_componentprotein-DNA complex
H0034462biological_processsmall-subunit processome assembly
H0034511molecular_functionU3 snoRNA binding
H0034774cellular_componentsecretory granule lumen
H0042162molecular_functiontelomeric DNA binding
H0042254biological_processribosome biogenesis
H0043085biological_processpositive regulation of catalytic activity
H0043229cellular_componentintracellular organelle
H0043564cellular_componentKu70:Ku80 complex
H0044877molecular_functionprotein-containing complex binding
H0045027molecular_functionDNA end binding
H0045087biological_processinnate immune response
H0045860biological_processpositive regulation of protein kinase activity
H0045892biological_processnegative regulation of DNA-templated transcription
H0048660biological_processregulation of smooth muscle cell proliferation
H0050769biological_processpositive regulation of neurogenesis
H0051575molecular_function5'-deoxyribose-5-phosphate lyase activity
H0051973biological_processpositive regulation of telomerase activity
H0060218biological_processhematopoietic stem cell differentiation
H0070198biological_processprotein localization to chromosome, telomeric region
H0070418cellular_componentDNA-dependent protein kinase complex
H0070419cellular_componentnonhomologous end joining complex
H0071398biological_processcellular response to fatty acid
H0071425biological_processhematopoietic stem cell proliferation
H0071475biological_processcellular hyperosmotic salinity response
H0071480biological_processcellular response to gamma radiation
H0071481biological_processcellular response to X-ray
H0090734cellular_componentsite of DNA damage
H1904430biological_processnegative regulation of t-circle formation
H1990830biological_processcellular response to leukemia inhibitory factor
H1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00915
Number of Residues15
DetailsPI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. VKgg.EDLRQDqrveQ
ChainResidueDetails
AVAL3752-GLN3766

site_idPS00916
Number of Residues21
DetailsPI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ShAlicIshWILgIgDRHlnN
ChainResidueDetails
ASER3907-ASN3927

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
CLYS144
HLYS665
CLYS265
CLYS332
CLYS660
CLYS665
HLYS144
HLYS265
HLYS332
HLYS660

site_idSWS_FT_FI2
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER255
ALYS3642
FLYS117
FLYS828
FLYS1209
FLYS1970
FLYS2259
FLYS3241
FLYS3260
FLYS3621
FLYS3638
CSER258
FLYS3642
CSER318
HSER255
HSER258
HSER318
GSER306
GSER560
ALYS3638

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CTHR535
FSER841
FSER1065
FSER2789
FSER3731
FSER3821
HTHR535
ASER841
ASER1065
ASER2789
ASER3731
ASER3821
FSER511
FSER687

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine; by PRKDC => ECO:0000269|PubMed:10026262, ECO:0007744|PubMed:24275569
ChainResidueDetails
CSER577
HSER577
BLYS338
BLYS461
GLYS31
GLYS331
GLYS338
GLYS461

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine; by PRKDC => ECO:0000305|PubMed:10026262
ChainResidueDetails
CSER579
HSER579

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphoserine; by PRKDC => ECO:0000269|PubMed:10026262
ChainResidueDetails
CSER580
HSER580

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by PRKDC => ECO:0000305|PubMed:10026262
ChainResidueDetails
CTHR715
HTHR715

site_idSWS_FT_FI8
Number of Residues14
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
CLYS195
HLYS532
HLYS534
HLYS566
HLYS669
HLYS688
GSER520
CLYS532
CLYS534
CLYS566
CLYS669
CLYS688
HLYS195

site_idSWS_FT_FI9
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:28112733
ChainResidueDetails
CLYS568
HLYS568
FTHR2638
FTHR2647

site_idSWS_FT_FI10
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
BLYS287
BLYS317
GLYS287
GLYS317

site_idSWS_FT_FI11
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733
ChainResidueDetails
ASER4026
BLYS556
GLYS556

218853

PDB entries from 2024-04-24

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