6KXS

Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR

Summary for 6KXS

Entry DOI	10.2210/pdb6kxs/pdb
EMDB information	0782
Descriptor	Immunoglobulin heavy constant mu, Immunoglobulin J chain, Polymeric immunoglobulin receptor, ... (5 entities in total)
Functional Keywords	immunoglobulin, pentamer, transcytosis, secreted, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	498249.35
Authors	Li, Y.,Wang, G.,Xiao, J. (deposition date: 2019-09-12, release date: 2020-02-05, Last modification date: 2021-12-15)
Primary citation	Li, Y.,Wang, G.,Li, N.,Wang, Y.,Zhu, Q.,Chu, H.,Wu, W.,Tan, Y.,Yu, F.,Su, X.D.,Gao, N.,Xiao, J. Structural insights into immunoglobulin M. Science, 367:1014-1017, 2020 Cited by PubMed: 32029689 DOI: 10.1126/science.aaz5425 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation