3FXI
Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex
Summary for 3FXI
| Entry DOI | 10.2210/pdb3fxi/pdb |
| Descriptor | Toll-like receptor 4, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (12 entities in total) |
| Functional Keywords | leucine rich repeat, glycoprotein, immune response, inflammatory response, innate immunity, membrane, receptor, transmembrane, secreted, immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 180250.88 |
| Authors | Park, B.S.,Song, D.H.,Kim, H.M.,Lee, J.-O. (deposition date: 2009-01-21, release date: 2009-03-03, Last modification date: 2023-11-01) |
| Primary citation | Park, B.S.,Song, D.H.,Kim, H.M.,Choi, B.-S.,Lee, H.,Lee, J.-O. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex Nature, 458:1191-1195, 2009 Cited by PubMed: 19252480DOI: 10.1038/nature07830 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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