3BIK
Crystal Structure of the PD-1/PD-L1 Complex
Summary for 3BIK
Entry DOI | 10.2210/pdb3bik/pdb |
Related | 3BIS |
Descriptor | Programmed cell death 1 ligand 1, Programmed cell death protein 1, GLYCEROL, ... (4 entities in total) |
Functional Keywords | co-stimulation, receptor-ligand complex, immunoglobulin-like beta-sandwich, t cell, b cell, programmed death, immune system, transmembrane, inhibitory receptor, glycoprotein, immunoglobulin domain, apoptosis |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein: Q9NZQ7 Membrane; Single-pass type I membrane protein: Q02242 |
Total number of polymer chains | 3 |
Total formula weight | 55672.53 |
Authors | Lin, D.Y.,Tanaka, Y.,Iwasaki, M.,Gittis, A.G.,Su, H.P.,Mikami, B.,Okazaki, T.,Honjo, T.,Minato, N.,Garboczi, D.N. (deposition date: 2007-11-30, release date: 2008-02-26, Last modification date: 2023-08-30) |
Primary citation | Lin, D.Y.,Tanaka, Y.,Iwasaki, M.,Gittis, A.G.,Su, H.P.,Mikami, B.,Okazaki, T.,Honjo, T.,Minato, N.,Garboczi, D.N. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc.Natl.Acad.Sci.Usa, 105:3011-3016, 2008 Cited by PubMed: 18287011DOI: 10.1073/pnas.0712278105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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