3BIK
Crystal Structure of the PD-1/PD-L1 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death 1 ligand 1 | polymer | 222 | 25396.8 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (human) | Programmed death ligand 1, PD-L1, PDCD1 ligand 1, B7 homolog 1, B7-H1, CD274 antigen |
| 2 | B, C (B, C) | Programmed cell death protein 1 | polymer | 134 | 15091.8 | 2 | UniProt (Q02242) Pfam (PF07686) | Mus musculus (house mouse) | Protein PD-1, mPD-1, CD279 antigen |
| 3 | D (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F, G (A, B, C) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
B, C: 25 - 157 (UniProt: Q02242)
| PDB | External Database | Details |
|---|---|---|
| Ala 24 | - | expression tag |
| Ser 83 | Cys 83 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 55580.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 55672.5 |
