2J67
The TIR domain of human Toll-Like Receptor 10 (TLR10)
Summary for 2J67
Entry DOI | 10.2210/pdb2j67/pdb |
Descriptor | TOLL LIKE RECEPTOR 10 (2 entities in total) |
Functional Keywords | tir, il-1, toll, tlr10, membrane, receptor, inflammatory response, toll-like receptor 10, innate immunity, immune response, leucine-rich repeat, glycoprotein, transmembrane |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Membrane; Single-pass type I membrane protein (By similarity): Q9BXR5 |
Total number of polymer chains | 2 |
Total formula weight | 42578.57 |
Authors | Stenmark, P.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-09-26, release date: 2006-09-27, Last modification date: 2023-12-13) |
Primary citation | Nyman, T.,Stenmark, P.,Flodin, S.,Johansson, I.,Hammarstrom, M.,Nordlund, P. The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer. J.Biol.Chem., 283:11861-, 2008 Cited by PubMed: 18332149DOI: 10.1074/JBC.C800001200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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