1XF0
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP
Summary for 1XF0
Entry DOI | 10.2210/pdb1xf0/pdb |
Related | 1RY0 1RY8 1S1P 1S1R 1S2A 1S2C |
Descriptor | Aldo-keto reductase family 1 member C3, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | alpha/beta barrel, beta-hairpin, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42330 |
Total number of polymer chains | 1 |
Total formula weight | 37985.07 |
Authors | Qiu, W.,Zhou, M.,Labrie, F.,Lin, S.-X. (deposition date: 2004-09-13, release date: 2004-10-26, Last modification date: 2023-08-23) |
Primary citation | Qiu, W.,Zhou, M.,Labrie, F.,Lin, S.-X. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues Mol.Endocrinol., 18:1798-1807, 2004 Cited by PubMed: 15087468DOI: 10.1210/me.2004-0032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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