1XF0
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aldo-keto reductase family 1 member C3 | polymer | 323 | 36896.2 | 1 | UniProt (P42330) Pfam (PF00248) | Homo sapiens (human) | Human 17beta-hydroxysteroid dehydrogenase type 5 |
| 2 | B (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (46936685) PubChem (71717786) PubChem (165382010) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (5885) PubChem (174001641) | |||
| 4 | D (A) | 4-ANDROSTENE-3-17-DIONE | non-polymer | 286.4 | 1 | Chemie (ASD) PubChem (16401731) PubChem (45038166) PubChem (45157398) PubChem (45358828) PubChem (51571550) PubChem (68200178) PubChem (70987809) PubChem (86310158) PubChem (86310317) PubChem (90350327) PubChem (118179606) PubChem (121467525) PubChem (124306669) PubChem (124905398) PubChem (139408315) PubChem (141834009) PubChem (142980352) PubChem (144685561) PubChem (144685562) PubChem (163076809) PubChem (1777655) PubChem (1777653) PubChem (1777654) PubChem (712379) PubChem (719687) PubChem (11869385) PubChem (12502771) PubChem (2193) PubChem (6128) PubChem (249335) PubChem (6432604) PubChem (6603719) PubChem (7059480) PubChem (7092858) PubChem (7092862) PubChem (10636976) PubChem (11862468) PubChem (11869386) PubChem (12502775) PubChem (12502776) | |||
| 5 | E (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36896.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1088.9 | |
| All* | Total formula weight | 37985.1 |
