1O4X
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Summary for 1O4X
| Entry DOI | 10.2210/pdb1o4x/pdb |
| Descriptor | 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', transcription factor Oct-1, ... (4 entities in total) |
| Functional Keywords | oct1, pou, pous, pouhd, sox2, hmg-box, transcription factors, dna, protein-dna complex, transcription-dna complex, transcription/dna |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus: P14859 P48431 |
| Total number of polymer chains | 4 |
| Total formula weight | 41446.89 |
| Authors | Clore, G.M.,Williams, D.C. (deposition date: 2003-07-17, release date: 2004-01-27, Last modification date: 2023-12-27) |
| Primary citation | Williams, D.C.,Cai, M.,Clore, G.M. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J.Biol.Chem., 279:1449-1457, 2004 Cited by PubMed: 14559893DOI: 10.1074/jbc.M309790200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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