1JPY
Crystal structure of IL-17F
Summary for 1JPY
Entry DOI | 10.2210/pdb1jpy/pdb |
Descriptor | interleukin 17F, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | cystine-knot, cytokine, t-cell derived, dimer, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 62729.58 |
Authors | Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A. (deposition date: 2001-08-03, release date: 2001-09-28, Last modification date: 2020-07-29) |
Primary citation | Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.P.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.F.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J., 20:5332-5341, 2001 Cited by PubMed: 11574464DOI: 10.1093/emboj/20.19.5332 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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