1JPY

Crystal structure of IL-17F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002225	biological_process	positive regulation of antimicrobial peptide production
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0005125	molecular_function	cytokine activity
A	0005126	molecular_function	cytokine receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006954	biological_process	inflammatory response
A	0016525	biological_process	negative regulation of angiogenesis
A	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
A	0019955	molecular_function	cytokine binding
A	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
A	0032663	biological_process	regulation of interleukin-2 production
A	0032675	biological_process	regulation of interleukin-6 production
A	0032677	biological_process	regulation of interleukin-8 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032761	biological_process	positive regulation of lymphotoxin A production
A	0042803	molecular_function	protein homodimerization activity
A	0045087	biological_process	innate immune response
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046982	molecular_function	protein heterodimerization activity
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051216	biological_process	cartilage development
A	0097400	biological_process	interleukin-17-mediated signaling pathway
A	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
A	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
B	0001819	biological_process	positive regulation of cytokine production
B	0002225	biological_process	positive regulation of antimicrobial peptide production
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0005125	molecular_function	cytokine activity
B	0005126	molecular_function	cytokine receptor binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006954	biological_process	inflammatory response
B	0016525	biological_process	negative regulation of angiogenesis
B	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
B	0019955	molecular_function	cytokine binding
B	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
B	0032663	biological_process	regulation of interleukin-2 production
B	0032675	biological_process	regulation of interleukin-6 production
B	0032677	biological_process	regulation of interleukin-8 production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032761	biological_process	positive regulation of lymphotoxin A production
B	0042803	molecular_function	protein homodimerization activity
B	0045087	biological_process	innate immune response
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046982	molecular_function	protein heterodimerization activity
B	0050829	biological_process	defense response to Gram-negative bacterium
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0051216	biological_process	cartilage development
B	0097400	biological_process	interleukin-17-mediated signaling pathway
B	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
B	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
X	0001819	biological_process	positive regulation of cytokine production
X	0002225	biological_process	positive regulation of antimicrobial peptide production
X	0002250	biological_process	adaptive immune response
X	0002376	biological_process	immune system process
X	0005125	molecular_function	cytokine activity
X	0005126	molecular_function	cytokine receptor binding
X	0005515	molecular_function	protein binding
X	0005576	cellular_component	extracellular region
X	0005615	cellular_component	extracellular space
X	0006954	biological_process	inflammatory response
X	0016525	biological_process	negative regulation of angiogenesis
X	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
X	0019955	molecular_function	cytokine binding
X	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
X	0032663	biological_process	regulation of interleukin-2 production
X	0032675	biological_process	regulation of interleukin-6 production
X	0032677	biological_process	regulation of interleukin-8 production
X	0032755	biological_process	positive regulation of interleukin-6 production
X	0032761	biological_process	positive regulation of lymphotoxin A production
X	0042803	molecular_function	protein homodimerization activity
X	0045087	biological_process	innate immune response
X	0045944	biological_process	positive regulation of transcription by RNA polymerase II
X	0046982	molecular_function	protein heterodimerization activity
X	0050829	biological_process	defense response to Gram-negative bacterium
X	0050830	biological_process	defense response to Gram-positive bacterium
X	0051216	biological_process	cartilage development
X	0097400	biological_process	interleukin-17-mediated signaling pathway
X	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
X	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
Y	0001819	biological_process	positive regulation of cytokine production
Y	0002225	biological_process	positive regulation of antimicrobial peptide production
Y	0002250	biological_process	adaptive immune response
Y	0002376	biological_process	immune system process
Y	0005125	molecular_function	cytokine activity
Y	0005126	molecular_function	cytokine receptor binding
Y	0005515	molecular_function	protein binding
Y	0005576	cellular_component	extracellular region
Y	0005615	cellular_component	extracellular space
Y	0006954	biological_process	inflammatory response
Y	0016525	biological_process	negative regulation of angiogenesis
Y	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
Y	0019955	molecular_function	cytokine binding
Y	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
Y	0032663	biological_process	regulation of interleukin-2 production
Y	0032675	biological_process	regulation of interleukin-6 production
Y	0032677	biological_process	regulation of interleukin-8 production
Y	0032755	biological_process	positive regulation of interleukin-6 production
Y	0032761	biological_process	positive regulation of lymphotoxin A production
Y	0042803	molecular_function	protein homodimerization activity
Y	0045087	biological_process	innate immune response
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0046982	molecular_function	protein heterodimerization activity
Y	0050829	biological_process	defense response to Gram-negative bacterium
Y	0050830	biological_process	defense response to Gram-positive bacterium
Y	0051216	biological_process	cartilage development
Y	0097400	biological_process	interleukin-17-mediated signaling pathway
Y	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
Y	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19838198

Chain	Residue	Details
A	ASN53
B	ASN53
X	ASN53
Y	ASN53

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