9ZUF

EBV gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - Global refinement

Summary for 9ZUF

• Entry DOI: 10.2210/pdb9zuf/pdb
• EMDB information: 74811
• Descriptor: EBV gB trimer with "deliDoP" mutations and I5350A2h, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: gb, glycoprotein b, herpesvirus, stabilization, stabilizing mutations, viral entry, vaccine, antigen, ebv, epstein-barr virus, prefusion, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: human gammaherpesvirus 4 (Epstein-Barr virus); More
• Total number of polymer chains: 3
• Total formula weight: 309702.63

Authors

McCallum, M.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2025-12-23, release date: 2026-11-04)

• Primary citation: McCallum, M.,Veesler, D.; Prefusion- stabilization of the Herpesvirus fusion protein enhances vaccine potency; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.4 Å)